Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UMLS:C0022116 (ischemia)
91,303 document(s) hit in 31,850,051 MEDLINE articles (0.05 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein Sep 5931 Mol 4297 ATP 4143 CA1 2829 caspase-3 2002 superoxide dismutase 1886 cytokine 1488 lactate dehydrogenase 1307 tumor necrosis factor 1236 nitric oxide synthase 1156 Bcl-2 1138 vascular endothelial growth factor 1127 TNF 1073 catalase 1051 insulin 1028 creatine kinase 1005 myeloperoxidase 898 MRI 832 IL-6 797 GSH 768 inducible nitric oxide synthase 759 ATPase 743 ADP 700 xanthine oxidase 695 albumin 691 p38 678 penumbra 667 hemoglobin 656 endoplasmic reticulum 638 cytochrome c 630 glial fibrillary acidic protein 626 collagen 622 CA3 617 NMR 598 glutathione peroxidase 557 gut 554 NMDA receptor 538 axonal 533 ERK1 529 VEGF 522 heme oxygenase-1 516 AMP 505 calcium channel 495 SOD 486 aspartate aminotransferase 447 alanine aminotransferase 445 MAPK 442 TNF-alpha 440 endothelin-1 436 angiotensin II 431 lipopolysaccharide 427 PI3K 421 ROS 416 LDH 414 p53 412 ERK 397 NADH 393 bradykinin 389 vascular endothelium 379 TLR4 378 CO2 373 GABA 371 brain-derived neurotrophic factor 366 endothelial nitric oxide synthase 365 JNK 365 She 362 heat shock protein 354 IL-10 353 interleukin-6 350 erythropoietin 347 renin 346 calpain 345 HSP70 333 eNOS 333 OGD 321 tissue plasminogen activator 319 cyclooxygenase 310 NAD 306 thrombin 306 chemokine 304 adenosine receptor 302 glutamate receptor 295 AKT 294 mTOR 291 PKC 289 adhesion molecule 286 c-Jun 285 ICAM-1 284 matrix metalloproteinase 283 cardiac muscle 279 calmodulin 262 P-selectin 260 p65 259 CBF 258 PLA 257 proximal tubule 248 PARP 248 Mal 240 tyrosine kinase 238 HO-1 236 cyclooxygenase-2 236 fibrinogen 234 phosphodiesterase 231 MMP-9 226 GSK 221 intercellular adhesion molecule-1 220 ubiquitin 220 LAD 214 myoglobin 214 caspase-9 212 Nrf2 210 neuronal nitric oxide synthase 209 tumor necrosis factor alpha 209 extracellular signal-regulated kinase 209 antioxidant enzyme 206 phosphatidylinositol 3-kinase 206 AST 205 AMP-activated protein kinase 202 COX-2 200 LPS 197 amyloid precursor protein 195 IL-8 194 STAT3 193 mitogen-activated protein 192 C-reactive protein 192 IL-1 188 CD31 186 glycoprotein 186 Vascular endothelial growth factor 182 LC3 182 cytochrome 181 opioid receptor 180 protein kinase B 180 Pol 180 c-fos 179 Ang II 179 HLA 177 NADPH 175 urokinase-type plasminogen activator 173 ANOVA 173 hepatocyte growth factor 172 CD18 169 serum albumin 169 CA2 169 CD11b 169 Fas 167 MMP-2 166 reserved 165 Gen 165 erythroid 164 proteasome 164 p38 mitogen-activated protein kinase 163 nerve growth factor 157 CSF 157 phospholipase A2 156 troponin I 154 caspase-8 153 CD34 150 MCP-1 149 CD4 149 more...

Disease ischemia 91303 stroke 8226 cerebral ischemia 6472 myocardial ischemia 6238 myocardial infarction 4832 cold 2794 hypertension 2716 diabetes 2714 coronary artery disease 2690 depression 2069 heart failure 2040 acute myocardial infarction 1742 atherosclerosis 1692 cancer 1446 tumor 1319 renal ischemia 1126 ventricular fibrillation 1098 coronary occlusion 1096 sepsis 1041 sepsis 1008 Alzheimer's disease 928 cardiovascular disease 901 GSH 769 cerebral infarction 709 acute renal failure 705 brain edema 692 renal failure 613 hyperglycemia 609 unstable angina 593 heart disease 569 renal disease 563 gangrene 551 epilepsy 536 claudication 535 vascular disease 523 plaque 517 subarachnoid hemorrhage 506 NAME 490 encephalopathy 477 congestive heart failure 458 celiac disease 456 coronary heart disease 448 vasculitis 444 SEM 430 dementia 427 obesity 422 cardiomyopathy 412 paraplegia 411 neuropathy 363 Evans 349 Parkinson's disease 347 hypoglycemia 345 intermittent claudication 341 cognitive impairment 339 preeclampsia 323 peripheral vascular disease 321 ventricular hypertrophy 319 intraocular pressure 308 type 2 diabetes 303 diabetic retinopathy 302 transient ischemic attack 297 glaucoma 293 compartment syndrome 280 retinopathy 272 bowel obstruction 272 Ischemic stroke 263 abdominal aortic aneurysm 262 pulmonary edema 255 aortic aneurysm 251 liver disease 247 arteriosclerosis 245 anemia 244 pulmonary hypertension 233 coma 230 hypercholesterolemia 229 migraine 229 blindness 227 cirrhosis 219 hyperlipidemia 218 proteinuria 217 multiple sclerosis 217 LAD 214 sickle cell disease 214 hepatocellular carcinoma 209 peritonitis 205 pancreatitis 204 chronic renal failure 199 systemic lupus erythematosus 197 acute tubular necrosis 195 Intestinal ischemia 195 cerebral palsy 194 acute pancreatitis 193 ischemic colitis 187 metabolic syndrome 185 necrotizing enterocolitis 175 lactic acidosis 174 renal insufficiency 171 infectious diseases 170 thrombocytopenia 168 carcinoma 160 neuroblastoma 157 pulmonary embolism 156 amyotrophic lateral sclerosis 155 hypertrophic cardiomyopathy 153 Huntington's disease 152 tumor growth 151 volvulus 149 inflammatory bowel disease 148 metastases 145 colitis 142 cytomegalovirus 136 MRS 130 Blocking 130 memory impairment 130 tubular necrosis 130 rheumatoid arthritis 129 hemiparesis 129 Buerger's disease 128 mitral regurgitation 126 dilated cardiomyopathy 124 deep vein thrombosis 122 hydrocephalus 122 myocarditis 120 HSP 120 Raynaud's phenomenon 119 coagulopathy 119 Pineal 119 asthma 118 hernia 118 fatty liver 117 malnutrition 116 dyslipidemia 115 moyamoya 115 Takayasu 115 PSS 114 ATM 113 Retinal ischemia 113 ischemic cardiomyopathy 113 chronic stable angina 112 dysplasia 112 chronic ischemic heart disease 110 status epilepticus 110 giant cell arteritis 109 Peripheral arterial disease 108 myelopathy 107 macular edema 107 Spinal cord ischemia 107 lupus 107 hepatitis 105 Crohn's disease 105 fits 103 cerebral vasospasm 101 disseminated intravascular coagulation 101 Infection 100 aortic stenosis 100 Transient ischemia 100 arthritis 100 HIV 100 glomerulosclerosis 99 coronary artery spasm 99 more...

Symptom pain 2131 angina 2065 functional recovery 1628 hypothermia 1565 anesthesia 1300 chest pain 918 seizures 888 abdominal pain 649 spasm 376 headache 309 collapse 277 fatigue 256 diarrhea 221 weakness 214 hypercapnia 184 vomiting 181 hyperoxia 176 thinning 153 starvation 144 syncope 142 dyspnea 140 nausea 139 analgesia 131 respiratory distress 128 flushing 106 discomfort 106 discomfort 105 vertigo 104 acute abdomen 98 paraparesis 97 paresthesia 89 dizziness 88 exhaustion 85 numbness 82 paresis 82 acute abdominal pain 74 exertional angina 73 pallor 65 asynergy 65 hemiplegia 60 colic 57 cyanosis 55 tinnitus 53 Anoxia 51 back pain 51 ataxia 51 constipation 50 oliguria 49 regurgitation 46 atypical chest pain 46 acidity 46 shortness of breath 46 erythema 45 epigastric pain 43 nausea and vomiting 42 memory loss 42 tremor 42 leg pain 41 myalgia 39 acute stress 38 spasticity 37 hypocapnia 36 anorexia 34 dysarthria 33 acute pain 32 neurological disability 30 lethargy 30 agitation 29 livedo 29 distraction 29 hemoptysis 28 overweight 28 exertional dyspnea 27 intestinal angina 26 neck pain 25 cough 25 ophthalmoplegia 24 incoordination 23 limb pain 20 cachexia 20 polyuria 20 Ill 19 myoclonus 18 sleepiness 18 pelvic pain 18 dystonia 18 low back pain 18 hypotonia 17 hypertonia 17 abdominal discomfort 17 dysesthesia 16 HSA 15 blurred vision 15 Pain at rest 15 exertional chest pain 14 arthralgia 14 leg edema 14 chorea 14 splenomegaly 13 twitching 13 rigors 13 sinus pressure 13 flank pain 12 cerebellar ataxia 12 tense 12 hepatomegaly 12 tingling 12 consciousness disturbance 11 muscle stiffness 11 knee pain 11 hand pain 11 precordial pain 11 Neuropathic pain 11 insomnia 11 tachypnea 10 bloating 10 ENT 10 asthenia 10 skin damage 9 Induced hypothermia 9 facial pain 9 shoulder pain 9 autodigestion 9 arm pain 9 Amaurosis fugax 9 testicular pain 8 heartburn 8 stridor 7 muscle cramps 7 intestinal bleeding 7 neuralgia 7 bradykinesia 7 dry eye 7 right upper quadrant pain 7 hyperesthesia 7 hypoproteinemia 7 abnormal gait 6 despair 6 muscle rigidity 6 Amputated 6 chills 6 syncopal episodes 6 sciatica 6 retching 6 hoarseness 6 lightheadedness 6 bone pain 6 neck stiffness 5 monoplegia 5 chronic constipation 5 prostration 5 groin pain 5 wheezing 5 Signs and Symptoms 5 facial droop 5 Visual disturbances 5 right lower quadrant pain 5 Decreased activity 5 dental pain 5 forgetfulness 5 more...

Drug Cardiovasc 3731 ROS 416 NADH 396 nitroglycerin 381 vitamin E 248 ascorbate 238 TTC 219 CSF 174 Monit 146 MAP 130 Heme 128 lysine 127 Nephron 124 caffeine 115 Dermatol 104 Ringer's solution 99 Fluorescein 86 Indomethacin 83 Adenosine triphosphate 83 Angiotensin II 80 IFN-gamma 78 Nitric Oxide 75 Portal 69 Nephron 67 Dial 67 Fluorescein 64 Propofol 63 IL-2 62 Iloprost 62 Glutathione 58 TAT 53 Ranolazine 53 Ranolazine 53 ETA 51 Albumin 50 EE2 50 citric acid 49 Ethanol 47 Captopril 43 ICI 43 Parkin 42 Parkin 42 CPR 40 p75 40 Vitamin E 40 Histamine 39 G-CSF 38 CaCl2 37 Cilostazol 36 BH4 36 CaCl2 35 ROC 35 CaCl2 35 CTA 34 Glucagon 33 Simvastatin 33 uPA 32 FAD 31 MgSO4 31 Tacrolimus 31 APD 30 CTX 30 Methylprednisolone 30 TAK 28 Gel 27 balanced salt solution 27 Sodium nitroprusside 26 CoCl2 26 CoCl2 26 Rosiglitazone 26 Amiloride 25 Amiloride 25 Ouabain 24 Fructose 24 Ginseng 23 Leaf 23 Clopidogrel 22 Urokinase 21 EPI 21 Aprotinin 20 Atropine 20 Estrogens 19 FeCl3 19 niacin 18 Viagra 18 Levosimendan 18 EPA 18 PCP 17 NH3 17 NAG 17 Glycerol 17 Aminoguanidine 17 Atenolol 17 Rosuvastatin 16 Phenytoin 16 Gelfoam 16 Streptokinase 16 Alanine 16 ENT 16 CIA 15 Viagra 15 CAM 14 Gelatin 14 Pravastatin 14 Bosentan 14 lactose 14 Bosentan 14 ABC 13 Indocyanine green 13 Propentofylline 13 RFP 12 Forskolin 12 Salicylate 12 Lovastatin 12 Abciximab 12 Asn 12 Bevacizumab 12 Papaverine 11 Clonidine 11 Prednisolone 11 Photofrin 11 Methylene blue 11 IL-1ra 11 Magnesium sulfate 11 Digitalis 11 TAC 11 Spectrum 11 Bifidobacterium 11 Alteplase 11 Adriamycin 11 Phentolamine 11 Triclosan 10 ampicillin 10 Theophylline 10 Rolipram 10 Desferal 10 pyridoxal phosphate 10 Serum albumin 10 Vinpocetine 10 Valsartan 10 Activin 10 Bumetanide 10 Spectrum 10 Kainic acid 9 Bivalirudin 9 Fentanyl 9 Paraffin 9 Molsidomine 9 Donepezil 9 Eptifibatide 9 Asthma 9 DPA 9 Lipiodol 9 Clofibrate 9 Alteplase 9 CTX 9 Alteplase 9 CVA 9 CCL 9 ACT 9 more...

Enzyme superoxide dismutase 2182 mitogen-activated protein kinase 1638 caspase-3 1568 lactate dehydrogenase 1386 creatine kinase 1315 catalase 1108 peroxidase 1063 protein kinase 924 protein kinase C 915 ATPase 803 alanine aminotransferase 790 xanthine oxidase 706 ERK 702 aspartate aminotransferase 649 NO synthase 596 glutathione peroxidase 570 tissue plasminogen activator 449 renin 346 AMP-activated protein kinase 334 PARP 323 NADPH oxidase 301 NOS 300 thrombin 296 NADPH oxidase 268 luciferase 262 GSK 245 complex I 240 phosphodiesterase 232 ACE 229 focal adhesion kinase 229 phospholipase A2 212 phosphatidylinositol 3-kinase 206 AST 204 calcineurin 195 MEK 191 heme oxygenase 189 urokinase-type plasminogen activator 171 proteasome 170 succinate dehydrogenase 168 AMPK 162 caspase-9 161 glutathione reductase 149 APC 143 cytochrome oxidase 143 AMPK 141 guanylate cyclase 138 pyruvate dehydrogenase 126 collagenase 123 caspase-8 122 caspase-1 122 xanthine dehydrogenase 118 adenylate cyclase 117 ATP synthase 115 ACS 114 alkaline phosphatase 113 phospholipase C 111 lipoxygenase 108 CaMKII 106 pyruvate dehydrogenase 105 pyruvate dehydrogenase 105 adenosine deaminase 104 MAP 104 adenosine deaminase 103 reverse transcriptase 103 acetylcholinesterase 100 CAD 99 CAD 99 CAD 99 phosphoinositide 3-kinase 92 kallikrein 85 glutathione S-transferase 85 thromboplastin 81 tyrosine hydroxylase 77 trypsin 75 ornithine decarboxylase 75 MIP 75 monoamine oxidase 74 diaphorase 72 glyceraldehyde-3-phosphate dehydrogenase 68 CPR 67 5'-nucleotidase 65 prolyl hydroxylase 64 phosphorylase 64 PKG 63 glyceraldehyde-3-phosphate dehydrogenase 61 choline acetyltransferase 61 TdT 60 cathepsin B 58 NQO1 58 beta-galactosidase 58 gamma-glutamyl transpeptidase 56 glyceraldehyde-3-phosphate dehydrogenase 55 plasmin 55 lipase 55 IKK 53 glyceraldehyde-3-phosphate dehydrogenase 53 TAT 53 glyceraldehyde-3-phosphate dehydrogenase 53 neutrophil elastase 53 glucose-6-phosphate dehydrogenase 52 NADPH-diaphorase 52 cathepsin D 52 glutamine synthetase 50 elastase 50 RNase 49 arginase 48 glutamate dehydrogenase 48 RNase 46 RNA polymerase 46 phosphofructokinase 45 citrate synthase 43 aldehyde dehydrogenase 43 CD10 43 aldose reductase 42 PDK1 41 SPT 41 aldehyde dehydrogenase 41 MMP 40 PDE 40 acid phosphatase 40 soluble epoxide hydrolase 39 glutamate dehydrogenase 39 hexokinase 39 glutamate dehydrogenase 39 SPT 39 cholinesterase 38 aldehyde dehydrogenase 38 aldehyde dehydrogenase 38 CPT 38 aldehyde dehydrogenase 38 aconitase 36 PRA 36 diamine oxidase 35 hyaluronidase 35 endonuclease 35 diaphorase 34 PTA 34 matrix metalloproteinase 9 33 enolase 32 P-glycoprotein 32 tissue kallikrein 31 m-calpain 31 transcriptase 31 matrix metalloproteinase 2 30 mu-calpain 30 TSA 30 hyaluronidase 29 MMP-3 29 adenylate kinase 29 peroxiredoxin 29 purine nucleoside phosphorylase 28 malate dehydrogenase 27 adenosine kinase 27 beta-glucuronidase 27 ceruloplasmin 26 NADH dehydrogenase 26 carbonic anhydrase 25 cdc2 24 succinic dehydrogenase 22 15-lipoxygenase 22 more...

Compound oxygen 11335 Dec 6181 calcium 5090 Cardiol 4896 glucose 4716 ATP 4148 Clin 3823 nitric oxide 2990 sodium 2634 glutamate 2485 water 2311 DNA 2023 potassium 1754 phosphate 1717 Cereb 1493 creatinine 1457 arginine 1106 hydrogen 1102 TNF 1073 nitrogen 894 CO2 839 Hearts 822 Hearts 815 GSH 807 GSH 807 ADP 805 iron 734 ADP 700 ADP 700 phosphocreatine 685 urea 608 AMP 542 H2O2 538 dUTP 525 prostacyclin 519 NMDA 491 acetate 474 Neuronal 451 Adenosine 448 NAD 416 His 408 cysteine 399 tyrosine 396 NADH 395 GABA 373 GABA 372 zinc 363 nitrate 349 ethanol 347 iodine 340 cAMP 337 cGMP 310 NAD 306 Glutamate 306 alanine 306 serine 304 Lactate 287 MDA 286 nicotinamide 273 salt 272 galactose 256 TTC 255 noradrenaline 246 N-acetylcysteine 245 sulfate 245 phosphorus 231 AMPA 223 glutamine 223 MTT 219 Melatonin 217 glycerol 203 Mg2+ 203 superoxide radical 198 H2S 195 PEG 189 leucine 187 MCA 182 copper 182 MCA 181 gamma-aminobutyric acid 178 Retinal 177 fluorine 177 NADPH 176 NADPH 175 GSSG 167 tryptophan 165 lysine 165 threonine 164 ADP-ribose 159 Asp 158 DMSO 157 PGE2 156 cyanide 156 prostaglandin E1 155 tryptophan 152 methionine 152 cobalt 151 FK506 151 Insulin 147 ASA 142 tryptophan 141 tryptophan 141 ammonia 140 5-HT 139 2-oxoglutarate 138 Heme 134 Salt 133 Resveratrol 127 Angiotensin II 126 adenylate 125 Verapamil 122 L-carnitine 122 CoA 121 Phe 121 manganese 120 bromide 120 PEG 120 Verapamil 118 caffeine 115 silver 114 ACS 113 ACS 113 aldosterone 112 Optimal 111 MAP 108 GMP 107 ACh 107 HPP 106 NH2 106 Glibenclamide 105 Dipyridamole 104 Dipyridamole 104 Dipyridamole 104 Dipyridamole 104 Dobutamine 102 Malondialdehyde 100 homocysteine 100 Heparin 100 EDTA 99 Ang II 99 Cyclosporine 99 EDTA 97 Sodium 97 HCl 97 selenium 96 Gly 96 MEK 96 Nifedipine 94 8-OHdG 92 Diltiazem 92 Diltiazem 92 barium 91 aspartic acid 91 carbonate 91 H2S 90 glutamic acid 89 Hematoxylin 88 cyclopentyl 86 PGE 86 hyaluronic acid 81 more...

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