Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0022116 (ischemia)
 91,303 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The authors have observed ten compartment syndromes of the leg. Nine occurred after tibial fractures, one after a contusive trauma. Early signs those of muscular and neural ischemia, with an acute pain when the toes are passively mobilised. The cast must be promptly removed. In 6 cases the two compartments were involved. In all cases the pulses were palpable. Arteriographs could occasionaly verify the integrity of the main arterial trunks. The treatment is based on early fasciotomies. It was realised in 5 cases, with good results when the fasciotomy was realised more than twelve hours after the trauma, the muscles were more or less necrotic. In one case all the muscles of the leg had to be excised.
Rev Chir Orthop Reparatrice Appar Mot 1979 Jun
PMID:[Compartment syndrome of the leg (author's transl)]. 16 61

The Tourniquet Ischemia Pain Ratio was developed as a measure of pain. The present study examined the relationship between the ratio and other measures thought to be relevant to a patient's perception of, and reaction to, chronic pain. The ratio was correlated with the patient's estimate of the pain, the perceived impact of the pain on daily life, the degree of reactive depression, and a measure of hypochondriasis. The ratio relates to both pain and hypochondriacal tendencies.
Percept Mot Skills 1978 Aug
PMID:Correlates of the tourniquet ischemia pain ratio. 70 41

The effect of tourniquet-induced ischemia was tested on magnitude scaling of supraliminal tactile stimuli (single-cycle sine waves) applied to the human hand contra- or ipsilaterally to the cuff. Magnitude estimations were not influenced on the contralateral side. In the ischemic hand there was a reduction of magnitude estimates beginning 12 min. after inflation of the cuff, independent of the stimulus intensity. The results indicate that peripheral noxious stimulation does not produce a nonsegmental reduction of tactile sensitivity. Moreover, it is suggested that the thickest afferent mechanoreceptive fibers (A-beta) have a major role in the mediation of tactile signals both at liminal and supraliminal levels.
Percept Mot Skills 1985 Oct
PMID:Effect of tourniquet-induced ischemia on magnitude scaling of tactile stimuli applied to the human hand. 406 19

Sixty-one cases of osteogenesis imperfecta were studied to try to discover the cause of metaphyseal and epiphyseal deformities. These deformities were noticeable in 8 cases out of 61 at the level of the upper and lower end of the femur in all cases and sometimes at the level of the lower end of the tibia and the upper end of the humerus. Several grades are described: First grade - protrusion of the growth plate into the epiphysis. Second grade - disorganization of the architecture of the epiphysis. Third grade - major deformity. It seems that the deformities are secondary to lesions of the growth plates. Several hypotheses are suggested. The authors consider that the main role is played by segmental fractures creating areas of ischemia in the epiphyses.
Rev Chir Orthop Reparatrice Appar Mot 1983
PMID:[Radiological study of epiphyseal abnormalities in osteogenesis imperfecta. Apropos of 61 cases]. 622 69

The authors have observed 11 cases of Volkmann's ischemia in the lower limb. The main deformity was of equinus. 10 patients were operated on. In 8 cases, arthrolysis was performed with good results in 7 cases. In 2 cases an ankle arthrodesis was done with one good result and one secondary amputation. The surgical technique of the arthrolysis is described. In most of the cases, tendon lengthenings, capsulotomy and fixation with an external fixator was required. This device was tolerated and it is concluded that it is worthwhile in severe ischaemic syndrome and that arthrolysis is preferred to arthrodesis.
Rev Chir Orthop Reparatrice Appar Mot 1981
PMID:[Deformities of the feet after Volkmann's ischemia in the lower limb (author's transl)]. 645 57

Traumatic hemipelvectomy is rarely observed, mostly because very few patients survive the initial trauma. We describe 2 cases of children who survived this trauma. The first was a 12 year-old boy who accidentally fell between a metro train and the platform. He had a severe open trauma of the pelvis with important hemorrhage. After a first operation to stop hemorrhage and do a cystotomy and a colostomy, ischemia of the lower limb led to an inter-ilio-abdominal amputation. Two months were necessary to heal this. A prosthesis was made 12 months after the accident, postponed by urinary problems. The boy also had a traumatic amputation of the left arm and an upper metaphyseal fracture of the humerus. The second case was that of an 8 year-old girl who suffered a complete traumatic amputation of the hemipelvis after a road accident. A secondary colostomy was performed because of a local infection. Once healing was achieved, the child was low to follow-up. In the literature, we found 36 survivors to this dreadful lesion (4 of them children). We analysed the different problems for the treatment of this trauma caused, and their short term consequences. An early evaluation of the lesions, rapid and intensive resuscitation, early decision to complete the traumatic amputation if necessary, with urinary and digestive derivation, are important elements towards eventual successful outcome of the treatment.
Rev Chir Orthop Reparatrice Appar Mot 1993
PMID:[Traumatic amputation of the lower limb and traumatic hemipelvectomy. Report of 2 cases in children and review of the literature]. 793 15

In order to investigate whether repetitive, low-level, muscular contractions or ischemia affect the ability of subjects to discriminate electrical stimuli delivered to the forearm musculature, a total of 25 experiments was performed on a group of five healthy subjects utilizing signal detection methodology. EMG needle electrodes were inserted into the forearm extensor musculature and the discriminability of two different pairs of constant current electrical stimuli were measured for sequential blocks of 100 trials, before and after the experimental interventions. Repetitive muscular activity consisting of a 15-min typing intervention at a rate of 60-80 wpm using a numeric keypad led to a significant decrease in the ability to discriminate the non-noxious stimulus pair in the block of trials immediately following the typing intervention, which then returned to pre-intervention discrimination levels following a 5-min break. The forearm ischemia significantly impaired the ability to discriminate both the noxious and non-noxious stimulus pair in the blocks of trials during and immediately after ischemia, which then returned to pre-intervention discrimination levels following a 5-min break. These experiments demonstrate that both repetitive muscular activity and ischemia acutely decrease the ability to discriminate intramuscular sensation. The mechanism may be due to decreased cortical processing, spinal cord sensitization or peripheral ischemia of large diameter afferents. These findings may be relevant to the physiological mechanisms underlying the development of overuse injuries.
Somatosens Mot Res 2002
PMID:The effects of repetitive contractions and ischemia on the ability to discriminate intramuscular sensation. 1239 75

Vessel damage during implantation of a total hip arthroplasty is exceptional (0.2-0.3% incidence). We observed a case of false aneurysm of the common femoral artery diagnosed in a pauci-symptomatic patient seven months after total hip arthroplasty. The vessel was damaged by a fragment of cement in contact with the artery. Treatment consisted in extraction of the cement fragment and insertion of a vascular prosthesis after dissection and ligature of the pseudoaneurysm. A review of the literature of vascular complications after prosthetic hip surgery was undertaken. Early complications include acute bleeding or ischemia while late complications include pseudoaneurysm or arteriovenous fistulization. Predisposing factors are: infection, repeated contact between the implants and arterial walls, overly medial reaming of the acetabulum, intrapelvic cement spikes, and use of Hohmann retractor. We detail here the clinical signs, diagnostic approach, and natural course of arterial false aneurysm resulting from intra-pelvic cement leakage.
Rev Chir Orthop Reparatrice Appar Mot 2004 Jun
PMID:[Arterial false aneurysm after total hip arthroplasty. A case report]. 1521 Dec 66

We report the case of traffic accident victim who suffered multiple injuries after being ejected from the vehicle. The patient suffered blunt trauma of the pelvis followed by acute ischemia of the lower limb. The initial work-up revealed minimally displaced fractures of the right and left obturator rings and the left sacral wing, as well as a non-displaced fracture of the anterior wall of the acetabulum. Computed tomography eliminated a compressive retroperitoneal hematoma. The mechanism of the injury was direct blunt trauma rupturing an atheroma plaque which led to thrombosis of the left common femoral artery. Thrombectomy three hours 30 minutes after onset of ischemia enabled complete sensorial and motor recovery. Awareness of this unusual type of injury can be helpful in conducting a rigorous physical examination to ensure rapid diagnosis and treatment.
Rev Chir Orthop Reparatrice Appar Mot 2006 Feb
PMID:[Acute limb ischemia and fracture of the pelvic ring: a case report]. 1660 20

A retrospective multicentric series of 54 cases of knee trauma with acute ischemia by popliteal artery injury were analyzed. These high-energy traumas involved 25 dislocations and 29 fractures, 11 involving distal femur, 15 the proximal tibia and 3 a floating knee. There were 45 men and 7 women, mean age 42 years. Thirty-three patients suffered multiple injuries. The knee injury was open in 25 cases and associated with sciatic paralysis in 32. Vascular repair was almost always achieved with bypass surgery. An external fixator was used in 39 patients. Vascular repair was unsuccessful in three cases requiring amputation, all three cases involving fractures. There were also six secondary amputations due to muscle necrosis or septic nonunion. The rate of complete recovery of the sciatic was 25%. The rate of nonunion was 37%, half due to infection. Outcome assessed at at least one year follow-up was moderate with frequent functional sequelae. The analysis of these results and data reported in the literature provided indications for diagnostic and therapeutic propositions.
Rev Chir Orthop Reparatrice Appar Mot 2006 Sep
PMID:[Dislocation and fractures around the knee with popliteal artery injury: A retrospective analysis of 54 cases]. 1708 47


1 2 Next >>