Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0022116 (ischemia)
 91,303 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Thromboangiitis obliterans or Buerger's disease is a rare arteritis affecting mainly young male smokers. Distal limb symptoms are well-known. Digestive manifestations, especially when inaugural, are less known and sometimes misdiagnosed. We report the case of a 37-year-old man who developed a large mesenteric infarct with diffuse ischemic colitis and ischemia in the hepatic artery field. Histopathological findings were consistent with thromboangiitis obliterans. Unexplained abdominal pain, even if inaugural, in young male smokers, should evoke the possibility of Buerger's disease.
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PMID:[Buerger's disease or thromboangiitis obliterans revealed by an enteric ischemia. Case report and literature review]. 1207 Apr 15

Leiden Factor V mutation, associated with resistance to activated protein C, is a prothrombotic state found in 20% of the patients with a first episode of deep-vein thrombosis. We report the case of a 30-Year-old woman with a history of intermittent abdominal pain who developed small bowel infarction requiring extensive small bowel resection. Biological search for prothrombotic disorder showed resistance to activated protein C due to homozygosity for the factor V Leiden mutation. Long-term anticoagulant therapy was initiated. Unexplained abdominal pain may be due to venous mesenteric ischemia, which can be associated with factor V Leiden mutation.
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PMID:[Chronic abdominal pain due to bowel ischemia in a patient with Leiden factor V mutation]. 1509 81