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Query: UMLS:C0022116 (ischemia)
 91,303 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

To make the ischemic effect on spinal cord clear, different vessels of the cord of 38 dogs, in 5 groups, were electrically cauterized individually or in combination. The animals in each group were sacrificed in due time periods, and the pathology of corresponding segment of each cord was observed grossly and under electron as well as light microscopes. The findings were described in this paper. As a consequence, the dogs in each group manifested paraplegia varying in degrees. However, dogs with the anterior cord artery and unilateral radicular artery, or both the anterior and posterior cord arteries cauterized developed irreversible, complete paraplegia. Cauterization of the anterior cord artery, or the posterior cord artery and unilateral radicular artery, or the radicular artery on both sides, gave rise to reversible, incomplete paraplegia. Anatomy of vessels of the spinal cord of other 9 dogs were dissected and studied. Their presence and distribution were cited and referred to the discussion about the effect of ischemia induced by electrifying them individually or in combination.
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PMID:[Experimental observations on spinal cord injury produced by electrifying the vessels of the cord in dogs]. 277 30

Referring to the experimental study on acute spinal cord injury, it is known that gray matter falls into an ischemia after injury, but opinions have not been unanimous whether or not the white matter falls into ischemia or hyperemia. The blood flow through the white matter varies according to the severity of the injury and degree of resultant paraplegia. Using rabbits, the authors carried out a series of experimental acute spinal cord impaction injury giving impactions at different strength stepwise, i.e., 400, 300, 200 and 100 gcf (g X cm X force) respectively at the 9th thoracic level of the spinal cord. Thus, upon observation of the paralysed levels and measurement of variable spinal cord blood flows according to the hydrogen clearance method, it was concluded as follows: In the 400 and 300 gcf impaction groups a complete paraplegia was observed with a decrease of spinal cord blood flow both in the gray and white matters. In the 200 gcf group mainly incomplete paraplegia was occurred, and while gray matter showed ischemia, white matter showed indefinite response consisting of both ischemia and hyperemia. In the 100 gcf impaction group the gray matter fell into ischemia, but white matter showed a biphasic increase of blood flow. From the above results it was noted that upon impaction causing complete paraplegia spinal white matter shows ischemia and upon impaction giving transient paraplegia blood flow increases. Ischemia thus does not appear to be a common behavior of spinal cord blood flow spinal cord injury.
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PMID:[Variations in spinal cord blood flow in stepwise spinal cord impaction injury]. 650 87