Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0022116 (ischemia)
 91,303 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 56-year-old male with a history of orthotopic cardiac transplantation secondary to cardiac sarcoidosis presented with recurrent episodes of syncope preceded by dizziness. While on telemetry, he had transient episodes of high-grade atrioventricular (AV) block that reproduced his prodrome. After excluding allograft rejection, ischemia, recurrent cardiac sarcoidosis, and vagally mediated block as a cause of high-grade AV block, adenosine testing was done which reproduced the spontaneous high-grade AV block. We concluded that hypersensitivity to endogenously released adenosine was the likely mechanism of AV block in our patient. This is the first reported case of adenosine testing in a cardiac transplant patient for diagnosing episodic high-degree AV block of unclear etiology.
Conn Med 2014 Oct
PMID:Transient high-grade atrioventricular block in an orthotopic cardiac transplant recipient. 2567 93

For many years tourniquets were perceived as dangerous due to the belief that they led to loss of limb because of ischemia. Their use in civilian and military environments was discouraged. Emergency medical responders were not taught about tourniquets and commercial tourniquets were not available. However, research by the United States military during the wars in Iraq and Afghanistan has demonstrated that tourniquets are safe life-saving devices. As a consequence, they have been widely deployed in combat situations and there are now calls for the use of tourniquets in the civilian prehospital setting. This article presents a report of the successful application of a tourniquet by the LIFE STAR crew to control bleeding that local emergency medical services (EMS) personnel could not control with direct pressure. Tourniquets should be readily available in public places and carried by all EMS.
Conn Med 2015 Oct
PMID:Use of a Tourniquet by LIFE STAR Air Medical Crew: A Case Report. 2663 Jul 5

Cardiacmyxomas arethemostcom- mon benign primary cardiac neoplasms, typically arising from the interatrial septum at the border of the fossa ovalis.'Ihey are generally divided into two anatomic types - ovoid and papillary myxomas -the latter ofwhich are less common but more frequently associated with embolic events. Despite their high embolic potential, however, widespread systemic and peripheral embolization, particularly to the lower extremities, is still uncommon. Furthermore, systemic tumor embolization secondary to trauma is only rarely reported and predominantly associ- ated with major blunt force trauma, such as motor vehicle accidents. Herein, we report a case of a 24-year-old male with widespread systemic and peripheral embolization of a left atrial myxoma, resulting in bilateral lower extremity ischemia, as well as multiple infarcts in major solid organs, in- cluding the heart, triggered by blunt chest trauma incurred during a basketball game.
Conn Med 2017 Mar
PMID:Widespread Systemic and Peripheral Embolization of Left Atrial Myxoma Following Blunt Chest Trauma. 2977 57

We describe a case of a 60-year-old female with a history of metastatic carcinoid disease with liver involvement who developed coronary vasospasm and mesenteric ischemia. The carcinoid syndrome is known for its cardiac involvement most well characterized by fibrous tissue deposits on the endocardium.(1,2) Case reports of coronary artery vasospasm have been previously described and hypothesized to be mediated by vasoactive amines and polypeptides synthesized by the tumor.(3-9) Intestinal ischemia is another reported complication of the carcinoid syndrome and is hypothesized to have a similar mechanism to that of the coronary vasospasm.(10-17) We have reviewed the literature and describe a case of coronary vasospasm and mesenteric ischemia in a patient on octreotide therapy. This is the first case in which we have identified concurrent coronary vasospasm and mesenteric ischemia in a patient with carcinoid disease.
Conn Med 2016 09
PMID:Coronary Vasospasm and Bowel Ischemia in a Patient with Metastatic Gastrointestinal Carcinoid. 2978 80


<< Previous 1 2