Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

---

Query: UMLS:C0022104 (irritable bowel syndrome)
8,033 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein IBD 1729 gut 1406 Sep 517 TNF 185 cytokine 180 Mol 138 5-hydroxytryptamine 104 IL-6 84 5-HT3 receptor 82 mast cell 79 corticotropin-releasing factor 78 HT3 74 IL-10 72 substance P 69 tumor necrosis factor 67 cholecystokinin 56 lymphoid 50 myeloperoxidase 50 IgA 47 5-HT4 47 guanylate cyclase 45 TNF-alpha 44 IL-8 43 CD4 40 IFN 40 opioid receptor 40 IgE 38 IL-17 38 DSS 38 5-HT4 receptor 34 lactase 32 somatostatin 32 serotonin transporter 31 C-reactive protein 31 beta-endorphin 31 insulin 31 interferon 29 serotonin receptor 29 She 28 IL-23 27 VP2 26 COX-2 25 TLR4 25 proton pump 25 lipopolysaccharide 25 NOD2 24 Pol 23 ATP 23 reserved 22 Cytokine 22 occludin 22 motilin 22 tryptophan hydroxylase 22 CRP 21 MRI 21 LPS 21 collagen 20 lactoferrin 20 HLA 20 inducible nitric oxide synthase 20 TRPV1 20 ASA 20 IL-4 19 IL-2 19 chloride channel 18 calcium channel 18 mucin 18 MAPK 18 albumin 18 uroguanylin 17 IFN-gamma 17 glucagon 17 amylase 17 ankylosing spondylitis 17 brain-derived neurotrophic factor 16 interleukin-6 16 ZO-1 16 CD8 15 IL-18 15 CRC 14 more...

Disease irritable bowel syndrome 8033 inflammatory bowel disease 2299 Crohn's disease 802 ulcerative colitis 747 colitis 493 depression 476 dyspepsia 449 gastrointestinal disease 365 celiac disease 287 cancer 279 fibromyalgia 262 gastroesophageal reflux disease 166 chronic pain 159 malabsorption 153 obesity 151 diabetes 148 colorectal cancer 147 enteropathy 126 organic disease 124 migraine 122 gastroenteritis 113 asthma 106 Colitis 106 chronic fatigue syndrome 103 diverticular disease 100 peptic ulcer 91 rheumatoid arthritis 87 interstitial cystitis 77 psychological distress 77 chronic disease 71 anxiety disorders 70 tumor 69 colon cancer 68 arthritis 67 lactose intolerance 63 Best 62 endometriosis 59 infectious diseases 58 gluten sensitivity 57 food allergy 56 gastroparesis 53 hypertension 53 ischemic colitis 52 mental illness 52 functional diarrhea 49 gastritis 48 psychological stress 47 major depressive disorder 46 pancreatitis 45 anemia 44 cold 42 osteoporosis 40 carcinoma 40 atopic dermatitis 40 diverticulitis 39 Inflammatory Bowel Disease 39 Clostridium difficile infection 38 DSS 38 psoriasis 38 DSS 38 fecal incontinence 37 gallstones 37 autism 37 gastrointestinal infection 37 cirrhosis 37 malnutrition 36 dysplasia 36 multiple sclerosis 34 enteritis 34 posttraumatic stress disorder 34 type 2 diabetes 33 Functional dyspepsia 33 ileus 33 necrotizing enterocolitis 33 primary sclerosing cholangitis 33 Colon 32 metabolic syndrome 32 panic disorder 32 incontinence 31 Colon 31 more...

Symptom diarrhea 1397 pain 1227 abdominal pain 1069 constipation 983 bloating 371 discomfort 269 discomfort 262 fatigue 169 chronic constipation 141 nausea 129 headache 128 vomiting 104 Wind 98 abdominal discomfort 92 pelvic pain 76 nausea and vomiting 47 heartburn 47 chest pain 46 analgesia 38 Gastrointestinal symptoms 38 epigastric pain 35 colic 31 back pain 29 Visceral pain 25 insomnia 25 myalgia 23 belching 23 anorexia 23 low back pain 21 arthralgia 18 spasm 18 anesthesia 18 bladder pain 18 Chronic pelvic pain 17 alexithymia 16 rectal pain 15 weakness 14 Functional abdominal pain 14 Chronic abdominal pain 13 overweight 13 change in stool 11 acute stress 11 dizziness 10 stigma 10 generalized pain 10 paresthesia 9 abdominal cramps 9 Ill 8 seizures 8 tinnitus 7 urinary frequency 7 regurgitation 7 ataxia 7 cough 7 numbness 7 sleepiness 6 intestinal pain 6 stomach pain 6 vestibulitis 6 lethargy 6 acute pain 6 dry eye 5 erythema 5 chronic cough 5 incoordination 5 GI pain 5 hepatomegaly 5 dyschezia 5 menopausal symptoms 5 Functional constipation 5 cachexia 5 chills 5 flushing 5 enuresis 4 tremor 4 asthenia 4 Food intolerance 4 vertigo 4 distraction 4 thinning 4 more...

Drug lactose 89 Bifidobacterium 62 Tegaserod 51 Alosetron 46 Tegaserod 45 Rifaximin 33 IL-2 19 IFN-gamma 17 Infliximab 17 Infliximab 17 caffeine 14 Dermatol 13 CSF 11 Lactose 10 Fructose 8 Asthma 8 Monit 8 Cisapride 8 lysine 7 CFS 7 Peppermint oil 7 Mesalazine 6 Aloe 6 Histamine 6 Cilansetron 6 Budesonide 6 Indomethacin 5 Renzapride 5 IL-11 5 ROC 5 ascorbate 5 Diphenhydramine 4 TAK 4 Portal 4 MAP 4 Lactase 4 Peppermint 4 Domperidone 4 Polycarbophil 4 Menthol 4 Raloxifene 3 Adalimumab 3 EPI 3 Calcium polycarbophil 3 ADR 3 Prednisolone 3 CAM 3 Leaf 3 Amitiza 3 Giardiasis 3 ROS 3 Trimebutine maleate 3 Check 3 IL-1ra 3 Pregabalin 3 Diurnal 3 Nephron 3 ENT 3 Ginger 2 Clonidine 2 p75 2 ICI 2 Estrogens 2 ACT 2 vitamin E 2 Vitamin B12 2 Ezlopitant 2 EE2 2 Alosetron hydrochloride 2 Colesevelam 2 NADH 2 G-CSF 2 ampicillin 2 Prifinium bromide 2 ABC 2 Cardiovasc 2 Asn 2 Omalizumab 2 Darifenacin 2 Crofelemer 2 more...

Enzyme peroxidase 55 guanylate cyclase 47 trypsin 38 lactase 32 mitogen-activated protein kinase 31 ERK 30 tryptophan hydroxylase 24 tryptase 23 transglutaminase 19 protein kinase 16 superoxide dismutase 16 catalase 14 focal adhesion kinase 13 ACS 10 myosin light chain kinase 9 sucrase 9 luciferase 8 glutathione peroxidase 8 alkaline phosphatase 7 reverse transcriptase 7 invertase 7 thiopurine methyltransferase 7 aspartate aminotransferase 7 protein kinase C 7 CYP3A4 7 lactate dehydrogenase 6 caspase-3 6 caspase-1 6 sucrase-isomaltase 6 thrombin 6 lysozyme 6 cholinesterase 5 P-glycoprotein 5 alpha-glucosidase 5 acetylcholinesterase 5 NO synthase 5 alanine aminotransferase 5 MIP 5 AMP-activated protein kinase 4 elastase 4 calcineurin 4 NOS 4 monoamine oxidase 4 APC 4 AST 4 RNA polymerase 4 lipase 4 pepsin 4 AMPK 3 hexosaminidase 3 MAP 3 adenylate cyclase 3 diamine oxidase 3 prolyl hydroxylase 3 phospholipase C 3 urease 3 S1 nuclease 3 ATPase 3 AMPK 3 CAD 3 urease 3 CAD 3 CAD 3 MEK 3 indoleamine 2,3-dioxygenase 2 VOR 2 NADPH oxidase 2 TdT 2 neutrophil elastase 2 lipoxygenase 2 LPL 2 glucose-6-phosphate dehydrogenase 2 arginase 2 enolase 2 proteasome 2 glucoamylase 2 monoacylglycerol lipase 2 inulinase 2 ACE 2 plasmin 2 more...

Compound Clin 901 Dec 511 5-HT 244 water 210 TNF 185 DNA 120 hydrogen 109 sodium 105 calcium 105 bromide 61 sulfate 59 glucose 53 acetic acid 52 oxygen 50 methane 40 DSS 39 barium 36 salt 33 tryptophan 33 tryptophan 31 tryptophan 31 nitric oxide 31 tryptophan 31 phosphate 29 acetate 27 iron 27 ethanol 26 vitamin D 25 Loperamide 24 ATP 23 ASA 22 serine 19 arginine 19 potassium 18 noradrenaline 18 Lubiprostone 18 DSM 17 nitrogen 16 Melatonin 16 glutamate 15 zinc 15 PEG 14 H2S 14 caffeine 14 ANCA 13 cAMP 12 selenium 12 ammonium 12 xylose 12 Curcumin 11 NIDA 11 CO2 11 tyrosine 11 Pac 11 Lactose 10 5-hydroxytryptophan 10 ACS 10 Ondansetron 10 butyric acid 10 ACS 10 cysteine 10 methionine 9 benzamide 9 acetonitrile 9 glutamine 9 Optimal 9 Salix 9 6-Mercaptopurine 9 galactose 9 GABA 8 ACTH 8 Cisapride 8 Fructose 8 GABA 8 Vitamin D 8 PGE2 8 cGMP 7 SPF 7 leucine 7 SDS 7 more...

---