Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0022104 (
irritable bowel syndrome
)
8,033
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
IBD
1729
gut
1406
Sep
517
TNF
185
cytokine
180
Mol
138
5-hydroxytryptamine
104
IL-6
84
5-HT3 receptor
82
mast cell
79
corticotropin-releasing factor
78
HT3
74
IL-10
72
substance P
69
tumor necrosis factor
67
cholecystokinin
56
lymphoid
50
myeloperoxidase
50
5-HT4
47
IgA
47
more...
Disease
irritable bowel syndrome
8033
inflammatory bowel disease
2299
Crohn's disease
802
ulcerative colitis
747
colitis
493
depression
476
dyspepsia
449
gastrointestinal disease
365
celiac disease
287
cancer
279
fibromyalgia
262
gastroesophageal reflux disease
166
chronic pain
159
malabsorption
153
obesity
151
diabetes
148
colorectal cancer
147
enteropathy
126
organic disease
124
migraine
122
more...
Symptom
diarrhea
1397
pain
1227
abdominal pain
1069
constipation
983
bloating
371
discomfort
269
discomfort
262
fatigue
169
chronic constipation
141
nausea
129
headache
128
vomiting
104
Wind
98
abdominal discomfort
92
pelvic pain
76
nausea and vomiting
47
heartburn
47
chest pain
46
analgesia
38
Gastrointestinal symptoms
38
more...
Drug
lactose
89
Bifidobacterium
62
Tegaserod
51
Alosetron
46
Tegaserod
45
Rifaximin
33
IL-2
19
IFN-gamma
17
Infliximab
17
Infliximab
17
caffeine
14
Dermatol
13
CSF
11
Lactose
10
Asthma
8
Cisapride
8
Fructose
8
Monit
8
lysine
7
CFS
7
more...
Enzyme
peroxidase
55
guanylate cyclase
47
trypsin
38
lactase
32
mitogen-activated protein kinase
31
ERK
30
tryptophan hydroxylase
24
tryptase
23
transglutaminase
19
protein kinase
16
superoxide dismutase
16
catalase
14
focal adhesion kinase
13
ACS
10
sucrase
9
myosin light chain kinase
9
luciferase
8
glutathione peroxidase
8
protein kinase C
7
alkaline phosphatase
7
more...
Compound
Clin
901
Dec
511
5-HT
244
water
210
TNF
185
DNA
120
hydrogen
109
sodium
105
calcium
105
bromide
61
sulfate
59
glucose
53
acetic acid
52
oxygen
50
methane
40
DSS
39
barium
36
salt
33
tryptophan
33
tryptophan
31
more...