Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0022104 (
irritable bowel syndrome
)
8,033
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Low concentration of
mannan-binding lectin
(
MBL
) has been related to unexplained spontaneous abortion (SA), which has also been observed in an increased frequency in patients with celiac disease (CD). In this study, plasma levels of
MBL
were determined in patients with CD and
irritable bowel syndrome
(
IBS
) in order to investigate whether there is an association of
MBL
levels and the occurrence of SA in these patients.
MBL
concentration was determined in 46 patients with CD (28 without and 18 with report of SA) and 38 patients with
IBS
(25 without and 13 with report of SA). A higher frequency of SA was observed in women with CD when compared to
IBS
patients (23.2 vs. 13.9%; P = 0.046). No significant difference was observed in
MBL
concentrations between patients with CD,
IBS
, and healthy controls, nor between patients with or without occurrence of SA. These results suggest that the serum levels of
MBL
and the occurrence of SA in women with CD and
IBS
are not causally related.
...
PMID:Mannan-binding lectin levels related to spontaneous abortion in Brazilian patients with celiac disease. 1847 32
