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Query: UMLS:C0022104 (irritable bowel syndrome)
 8,033 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A detailed history and examination removes much of the vagueness from the symptoms of irritable bowel syndrome patients. The syndrome is much more homogeneous than suggested by the patient's complaints. Detailed questioning and examination contribute to further information in over two-thirds of patients. Examination reveals previously unrecognized abnormalities of bowel habit in over one-third of the patients. A proper history and examination remain foremost investigative weapons in the diagnosis of irritable bowel syndrome.
J Clin Gastroenterol 1983 Dec
PMID:Detailed history and examination assist positive clinical diagnosis of the irritable bowel syndrome. 666 40

One hundred fifty-four of 184 consecutive patients diagnosed as having the irritable bowel syndrome were followed for an average of 29 months. Diagnosis was based on history, physical examination, and sigmoidoscopy. Seventy-eight percent of the patients had some form of gastrointestinal radiologic investigation, the majority ordered by the referring physicians. Treatment was restricted to reassurance, explanation, and a high-fiber diet. Twenty-five patients continued to take or had prescribed by their family physicians antispasmodics, minor tranquilizers, or laxatives. Eleven patients required psychiatric referral or major psychotropic medication. At follow-up, 79% felt their symptoms were better, much better, or gone completely. Outcome was not affected by identified psychiatric problems. During follow-up, an organic cause for symptoms was identified in six patients. The change in diagnosis was the result of clinical suspicion plus failure to respond to conservative therapy.
J Clin Gastroenterol 1983 Dec
PMID:Management of the irritable bowel syndrome: a personal view. 666 41

77 hospitalized patients with chronic unspecific abdominal complaints, in whom any other organic disease had been previously excluded, were investigated for lactose malabsorption; they were subdivided into two groups: 46 patients complaining primarily of colicky abdominal pain and/or intermittent diarrhoea (group 1) and 31 patients presenting with dyspepsia as the predominant symptom (group 2). To establish the exact prevalence of isolated lactase deficiency in the healthy adult population served by our hospital, 40 Italian adult healthy subjects were also studied. The prevalence of lactose malabsorption was significantly higher (p less than 0.005) in patients of the 1st group than in patients of the 2nd group, and in the healthy adult population seen at our hospital (74% vs 35.5% and 37.5%, respectively). Furthermore a high prevalence of lactose intolerance, determined by means of a three-week diet trial (lactose free-diet versus normal diet), was documented among lactose malabsorbers of the 1st group. We concluded therefore that lactose intolerance is a factor in some Italian adult patients who suffer from long-standing aspecific abdominal discomfort, and it should be always considered in these patients, especially when colicky abdominal pain and diarrhoea are present, before the diagnosis of irritable bowel syndrome is made.
Hepatogastroenterology 1983 Dec
PMID:Lactose intolerance in adults with chronic unspecific abdominal complaints. 667 46

Proctaglia fugax is a sudden severe pain in the rectum lasting a few seconds or minutes. It seems to occur in about 14% of apparently healthy adults, and there is some evidence that it is associated with the irritable bowel syndrome. The pathogenesis of the pain is unknown. Attacks are usually too brief and infrequent to warrant treatment, and no prophylactic drug has been proven effective. It is incurable but harmless, and tends to become less frequent with age.
Dig Dis Sci 1981 Dec
PMID:Proctalgia fugax. 703 Jun 75

Intestinal transit time was studied in two groups of 8 patients with irritable colon. In the first group, the time was longer than normal, whereas in the second it was accelerated. Three subjects in each group received a placebo, while the other five received 60 mg/day bromopride for 15 days. No change in transit time was noted in the controls. Two subjects in Group I displayed a significant reduction in transit time after bromopride, while deceleration and normalisation were observed in 4/5 patients in Group II.
Minerva Med 1981 Dec 08
PMID:[Changes in intestinal transit time induced by bromopride in functional diseases of the colon]. 703 16

Histological gastritis was present in nearly two-thirds of consecutive patients with lower intestinal irritable bowel (irritable colon) syndrome. The presence of gastritis had no relationship to upper intestinal symptoms; we believe that upper intestinal symptoms in these patients are therefore unlikely to be due to coexistent gastritis. Abnormal pyloroduodenal motility with consequent abnormal bile reflux or clearance may account for gastritis in patients with irritable colon. This study, admittedly uncontrolled, provides further indirect evidence to support the concept of a widespread neuromuscular abnormality throughout the gastrointestinal tract in irritable bowel syndrome patients who have predominantly colonic symptoms.
J Clin Gastroenterol 1982 Dec
PMID:The prevalence and significance of gastritis in patients with lower intestinal irritable bowel (irritable colon) syndrome. 716 65

Long-term follow-up evidence for biofeedback treatment of headaches, Raynaud's disease, essential hypertension, and the irritable bowel syndrome was reviewed. Acknowledging the difficulties with cross-study comparisons, the following general success rate were determined: primary idiopathic Raynaud's disease--70%, or better; vascular headache--70%, or better; mixed headache--about 60%; and muscle contraction headache--50%, or less. With relatively fewer patients, successful outcomes with the irritable bowel syndrome and secondary Raynaud's phenomenon were roughly 60% and 40%, respectively. Few cases of clinically significant long-term decreases in diastolic blood pressure were demonstrated; however, the need for medication was reduced or eliminated in some patients. There were indications that biofeedback combined with psychotherapy resulted in highest success rates. No differences were found in effectiveness between biofeedback, other relaxation techniques, and biofeedback in combination with relaxation techniques--all had essentially comparable rates of success. No correlations between physiological and psychological measures of condition at follow-up were reported. Implications and interpretations of these findings are discussed.
Biofeedback Self Regul 1982 Dec
PMID:Biofeedback treatment for headaches, Raynaud's disease, essential hypertension, and irritable bowel syndrome: a review of the long-term follow-up literature. 716 83

In order to investigate the possible involvement of gastrointestinal hormones in functional disorders of the digestive tract, serum motilin, neurotensin and gastrin levels in their response to oral intake of fat and glucose were examined in patients with irritable colon syndrome and dumping syndrome. The following results were obtained. (1) Basal serum motilin levels were higher in patients with irritable colon syndrome than in normal subjects, and remained high after ingestion of either 50 g of butter or 50 g of glucose. (2) No consistent response in serum neurotensin levels was found in patients with irritable colon syndrome or in normal subjects. (3) An immediate increase in serum gastrin levels was found in response to fat ingestion both in patients with irritable colon syndrome and in normal subjects, but there was no difference between these two groups. (4) In a patient with typical dumping syndrome, a markedly high level of fasting serum motilin was found, and the level increased further after the oral intake of glucose. These findings suggest that motilin may be involved in the irritable colon syndrome and dumping syndrome.
Endocrinol Jpn 1980 Dec
PMID:Serum motilin in gastrointestinal diseases. 722 18

Data concerning a random cohort of 1,119 70-year-old subjects were analyzed to evaluate the association between Upper Dyspepsia and Irritable Bowel Syndrome and functional ability. Seven hundred and thirty-four subjects were interviewed about abdominal symptoms and were visited at home by an occupational therapist who evaluated their functional ability. Among the survivors, 94% participated in a follow-up study five years later. Functional ability was registered on validated scales constructed for its measurement in a normal elderly population. It was found that both syndromes occurred more often among subjects with reduced functional ability. A significant association was found between the occurrence of Upper Dyspepsia and a reduction of mobility and lower limb function, and between reduced functional ability and Irritable Bowel Syndrome at the five-year follow-up. It is concluded that abdominal syndromes are associated to functional ability, suggesting that there is a diffuse disorder affecting both smooth and striated muscles.
Aging (Milano) 1994 Dec
PMID:Abdominal syndromes and functional ability in the elderly. 774 15

A sex stratified random sample of 70-year-old Danes living in Glostrup County was interviewed about abdominal symptoms in order to assess 1) the prevalence of colon-related symptoms and irritable bowel syndrome among the elderly and 2) to which extent different definitions of irritable bowel syndrome identify different subjects as having irritable bowel syndrome. Abdominal pain occurred with a prevalence of 17% among men and 28% among women (p < 0.01), distension with a prevalence of 29% and 40%, borborygms with a prevalence of 16% and 27%, and varying consistency of stool with a prevalence of 25% and 28%, for men and women respectively. The median number of bowel movements a week was seven for both sexes. Prevalence of irritable bowel syndrome was 3-18% among men and 6-32% among women according to various definitions. The subpopulations identified by various definitions of irritable bowel syndrome had less than 50% of the subjects in common.
Ugeskr Laeger 1994 Dec 19
PMID:[Symptoms of irritable colon among the elderly]. 783 36


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