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Query: UMLS:C0022104 (irritable bowel syndrome)
 8,033 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Irritable bowel syndrome patients often complain of urinary symptoms such as frequency, urgency, and dysuria, raising the possibility of inappropriate referral to the urologist. To resolve this issue, the prevalence of irritable bowel syndrome was compared in patients attending urological and control clinics (dermatology and ENT). The overall prevalence of irritable bowel syndrome was 31.2% in the urological clinic compared with 21.2% in the controls (P < 0.001), but striking, differences emerged, depending on presenting complaint. Irritable bowel symptoms were particularly common in patients presenting with loin pain (male: 40.9%, P = 0.004; female: 50%, P = 0.03), dysuria (male: 43.8%, P = 0.007; female: 46.2%, P = 0.01) and frequency/urgency (male: 31.7%, P = 0.002; female: 42.4%, P = 0.006), and the male/female prevalence was 24% and 44%. These results suggest that in irritable bowel syndrome, urinary symptoms including loin pain can present diagnostic dilemmas in both the gastroenterological and urological setting, underlining the importance of specialists in these fields working together in order to define better ways of managing such patients.
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PMID:High prevalence of irritable bowel syndrome in patients attending urological outpatient departments. 905 26

Chronic pelvic pain is a puzzling disease entity. The pathophysiological mechanisms of chronic pelvic pain are not clear and current treatment strategies are often not successful, leaving patients as well as health care providers frustrated. In a subgroup of patients with chronic pelvic pain (e.g., interstitial cystitis, irritable bowel syndrome, vulvar vestibulitis, prostatodynia/prostatitis, and loin pain/hematuria syndrome) inflammatory changes are observed, for which no etiology has been identified. These inflammatory changes might be due to neurogenic inflammation. Applying the concept of neurogenic inflammation to chronic pelvic pain provides new insights into the pathophysiological mechanisms of these pain syndromes, makes it possible to account for the heterogeneity and variability observed in the clinical presentation, and might lead to the development of novel therapies.
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PMID:Neurogenic inflammation and chronic pelvic pain. 1146 5