Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0022104 (irritable bowel syndrome)
 8,033 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Irritable bowel syndrome patients often complain of urinary symptoms such as frequency, urgency, and dysuria, raising the possibility of inappropriate referral to the urologist. To resolve this issue, the prevalence of irritable bowel syndrome was compared in patients attending urological and control clinics (dermatology and ENT). The overall prevalence of irritable bowel syndrome was 31.2% in the urological clinic compared with 21.2% in the controls (P < 0.001), but striking, differences emerged, depending on presenting complaint. Irritable bowel symptoms were particularly common in patients presenting with loin pain (male: 40.9%, P = 0.004; female: 50%, P = 0.03), dysuria (male: 43.8%, P = 0.007; female: 46.2%, P = 0.01) and frequency/urgency (male: 31.7%, P = 0.002; female: 42.4%, P = 0.006), and the male/female prevalence was 24% and 44%. These results suggest that in irritable bowel syndrome, urinary symptoms including loin pain can present diagnostic dilemmas in both the gastroenterological and urological setting, underlining the importance of specialists in these fields working together in order to define better ways of managing such patients.
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PMID:High prevalence of irritable bowel syndrome in patients attending urological outpatient departments. 905 26

A large proportion of irritable bowel syndrome (IBS) patients also complain of other functional disorders, such as headache, noncardiac chest pain, low back pain, and dysuria. Some of these features, particularly headache, may have a negative influence on the outcome of IBS. In a large proportion of female IBS patients, sexual intercourse triggers the symptoms, and frequently IBS symptoms exacerbate during menses. These gynecological-type symptoms often mislead the patients to the gynecological clinic, which may imply unnecessary investigations and inappropriate treatments. The diagnostic criteria of the fibromyalgia syndrome include IBS, and hence, the apparent relationship of both syndromes is difficult to analyze. On the other hand, no convincing evidence has been produced to date to sustain an association between IBS and the chronic fatigue syndrome.
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PMID:Nongastrointestinal disorders in the irritable bowel syndrome. 1089 28

65 patients with knee and hip joints osteoarthrosis with concomitant urinary infection and/or irritable colon syndrome were randomized into three groups: group 1 (21 patients) received doxicyclin 200 mg/day with nistatine for three weeks with 3-week interval between the courses and bifidum-bacterin administration between the courses and after the treatment; group 2 (22 patients) received biseptol 1920 mg for 3 weeks then 960 mg 10 days a month; group 3 (22 patients) consisted of controls who received no antibacterial drugs. The effect was assessed upon randomization, 3 weeks, 3, 6 and 12 months after the treatment. It was established that antibacterial treatment not only attenuated dysuria and dyspepsia but also had a significant positive effect on osteoarthrosis especially in patients with x-ray stage II, allowed to reduce doses of nonsteroid antiinflammatory drugs. Further studies will help specify the role of the infection factor in development of osteoarthrosis and potential of antibacterial treatment.
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PMID:[Antibacterial drugs in the treatment of osteoarthrosis: results of a prospective randomized trial]. 1149 Apr 18