Gene/Protein
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Pivot Concepts:
Gene/Protein
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Symptom
Drug
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Target Concepts:
Gene/Protein
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Query: UMLS:C0022104 (
irritable bowel syndrome
)
8,033
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The current study describes the successful administration of hypnotherapy with a subject suffering from refractory
Irritable Bowel Syndrome
(
IBS
) and
Generalized Anxiety Disorder
(
GAD
). The subject had suffered from
IBS
for 30 years and had unsuccessfully pursued multiple psychological treatments, both traditional and non-traditional. He was referred to the Center for Stress and Anxiety Disorders and commenced hypnotherapy directed primarily at the
IBS
symptoms. After 6 treatment sessions, his
IBS
symptomatology had improved 53%. He stopped treatment at that point and continued autohypnosis with the aid of treatment audiotapes provided by his therapist. Follow-up at 6 months indicated continued improvement (70%). A 2-year follow-up revealed an improvement of 38% in
IBS
symptomatology. Concurrent levels of depression and anxiety had also substantially decreased. Hypnotherapy is shown to be a viable, palatable, and enduring treatment option for an individual who had been refractory to many previous therapies.
...
PMID:Hypnotherapy and refractory irritable bowel syndrome: a single case study. 1211 13
Background/Aims:
Anxiety and depression are common comorbid psychiatric disorders in
IBS
patients, but the population-level determinants influencing these comorbidities in
IBS
patients are poorly understood. We sought to determine whether there was an association between comorbid affective disorders and socioeconomic status among
irritable bowel syndrome
(
IBS
) patients.
Methods:
We assembled a retrospective cohort of 1074
IBS
patients with comorbid
Generalized Anxiety Disorder
(
GAD
) and/or Major Depressive Disorder (MDD) seen at two tertiary referral centers between 2007 and 2015.
IBS
patients with comorbid
GAD
and/or MDD were matched 3:1 by age, sex, and race to controls with
IBS
and no history of comorbid
GAD
and/or MDD. Socioeconomic status was approximated by patient zip codes.
Results:
IBS
patients in the lowest socioeconomic group were more likely to be diagnosed with
GAD
and/or MDD compared to controls (OR = 1.38,
p
= .0004). The median average per capita income for comorbid
GAD
/MDD
IBS
patient cohort was also significantly lower than the control
IBS
patient cohort ($39,880.50 vs. $41,277.00,
p
= .02).
Conclusions:
Among
IBS
patients, the presence of comorbid
Generalized Anxiety Disorder
and/or Major Depressive Disorder is associated with lower socioeconomic status and lower average per capita income. These findings speak to a biopsychosocial model of illness, which should be considered by clinicians in the care of
IBS
patients.
...
PMID:Lower socioeconomic status is associated with an increased prevalence of comorbid anxiety and depression among patients with irritable bowel syndrome: results from a multicenter cohort. 3153 48