Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0022104 (
irritable bowel syndrome
)
8,033
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The purpose of this investigation is to determine if the high prevalence rates of major depression, panic disorder, and agoraphobia found in tertiary-care studies of
irritable bowel syndrome
and medically unexplained gastrointestinal symptoms are also found in the general population. Structured psychiatric interviews on 18,571 subjects from the NIMH Epidemiologic Catchment Area (ECA) Study were reviewed for prevalence of gastrointestinal distress symptoms and selected psychiatric disorders. Medically unexplained gastrointestinal symptoms had a high prevalence in the general population (6-25%). When compared with those reporting no gastrointestinal symptoms, subjects who report at least one of these symptoms were significantly more likely to have also experienced lifetime episodes of major depression (7.5% vs 2.9%), panic disorder (2.5% vs 0.7%), or agoraphobia (10.0% vs 3.6%). Subjects with two gastrointestinal symptoms had even higher lifetime rates of depression (13.4%), panic (5.2%), or agoraphobia (17.8%). Lifetime rates of affective and
anxiety disorders
in the general population are higher in subjects with gastrointestinal symptoms compared with subjects without gastrointestinal symptoms. An even higher prevalence of affective and
anxiety disorders
is found in patients with medically unexplained gastrointestinal symptoms in tertiary-care clinics. Future studies are needed in primary-care populations where prevalence rates of psychiatric illness are probably intermediate between those of the general population and tertiary care.
...
PMID:Comorbidity of gastrointestinal complaints, depression, and anxiety in the Epidemiologic Catchment Area (ECA) Study. 153 Nov 68
To understand the content of ambulatory family practice and find effective ways to improve clinical service, education and research in the Department of Family Medicine of Kaohsiung Medical College Hospital, we surveyed 14,064 patients from Jan. 1984 to Feb. 1991 and analysed (a) their basic demographic data including sex, age, insurance type, source and residential district and (b) clinical health problems covering 25,679 diagnoses and 148,994 diagnostic visits. Clinical health problems were recorded by the ICHPPC-2 code system. Results of basic demographic survey were as follow: 49.1% of patients was male and 50.9% female; 58.9% fell in the age group of 16-40 years and 22.4%, 12.0% and 6.7% of patients fell into the age groups of 41-65, under 16 and over 65 years respectively; 62.8% was insured usually by labor insurance and 26.9% had no insurance; the commonest referrals were other patients, colleagues, company personnel, doctors, media ... etc.; 58.8% lived in Kaohsiung City and 19.6% in Kaohsiung county. As for clinical health problems, the data showed that the commonest thirty diagnoses encountered at our clinic accounted for 69.3% of 25,679 diagnoses and the commonest ten diagnoses in descending order were medical health examination, acute URI, abdominal pain, uncomplicated hypertension, prophylactic immunization, hepatitis B carrier, back pain,
anxiety disorder
, viral hepatitis and
irritable bowel syndrome
. By calculating the average value of each diagnosis in a sample of 148,994 diagnostic visits to evaluate the habits of practice, we found that the commonest ten diagnostic visits at clinic in descending order were diabetes mellitus, hypertension involving target organ, uncomplicated hypertension, gout, hyperthyroidism, duodenal ulcer, tuberculosis, lipid metabolism disorder, other peptic ulcer and depressive disorders; all were chronic diseases. We concluded it was very important and helpful for the development of family medicine program and primary care unit to understand the content of their own ambulatory practice.
...
PMID:[The content of ambulatory family practice in Kaohsiung Medical College Hospital]. 156 Apr 75
Structured psychiatric interviews and psychological self-report measures were administered to 28 patients with
irritable bowel syndrome
and 19 patients with inflammatory bowel disease. Significantly more of the patients with
irritable bowel syndrome
had lifetime diagnoses of major depression, somatization disorder, generalized
anxiety disorder
, panic disorder, and phobic disorder. They had significantly more medically unexplained somatic symptoms, and most had suffered from psychiatric disorders, particularly
anxiety disorders
, before the onset of their irritable bowel symptoms.
...
PMID:Psychiatric illness and irritable bowel syndrome: a comparison with inflammatory bowel disease. 205 50
Using a reliable and valid structured diagnostic interview scale (ADIS-R), and patients with careful medical characterization, we found significantly more diagnosable psychopathology, particularly
anxiety disorders
, among treatment seeking patients with
irritable bowel syndrome
than among comparable age and sex samples of treatment seeking patients with Inflammatory Bowel Disease. Significant differences were also found on the Hamilton Anxiety Rating Scale and Hamilton Rating Scale for Depression between
IBS
patients and the
IBD
patients and controls, who did not differ. Comparable levels of psychiatric disorder among parents of probands were found in all three groups. The results are consistent with Latimer's (1983) notion of
IBS
patients being a subclass of 'neurotics'.
...
PMID:The role of anxiety and depression in the irritable bowel syndrome. 225 98
Symptoms of gastrointestinal distress, including those of
irritable bowel syndrome
, were reported more frequently by patients with panic disorder than by nonanxious controls. Five of 30 subjects with panic disorder met criteria for
irritable bowel syndrome
, the onset of which coincided with the onset of panic disorder. Effective treatment for the
anxiety disorder
was accompanied by a reduction in gastrointestinal symptoms in all subjects.
...
PMID:Reduction of gastrointestinal symptoms following treatment for panic disorder. 230 Jun 59
The symptoms of
irritable bowel syndrome
(
IBS
) are usually a subset of a broader problem that meets DSM-III criteria for depression,
anxiety disorder
, somatization disorder, or adjustment disorder. A biopsychosocial perspective that addresses multigenerational family patterns of anxiety, depression, and somatization of stress suggests guidelines for understanding and treating patients with
IBS
symptoms. Effective treatment focuses primarily on helping patients cope with emotional disorders and psychosocial stressors, and secondarily on direct symptom relief. Psychotherapy is a valuable adjunct to medical treatment. The medications most likely to yield lasting benefits are the antidepressants.
...
PMID:Irritable bowel syndrome. Toward a biopsychosocial systems understanding. 304 2
This paper reports on verbal content analysis measures (Gottschalk-Gleser method) of anxiety and hostility in duodenal ulcer, irritable bowel and generalized
anxiety disorder
patients, who were also administered the Eysenk Personality Inventory (EPI), and Beck and Zung depressiveness scales.
Irritable bowel
patients expressed significantly more death anxiety than the other groups in a 5-min free speech sample, while
anxiety disorder
patients scored highest on hostility directed inwards. In the whole sample, EPI neuroticism scores correlated with depressiveness scores and hostility measures appeared intercorrelated. Factor analyses with Varimax rotation revealed a similar clustering of variables. Results tend to suggest that irritable bowel patients are closer to
anxiety disorder
than to duodenal ulcer ('psychosomatic') patients in terms of intensity and patterning of affect expression.
...
PMID:Content category analysis of affective expression in irritable bowel, duodenal ulcer and anxiety disorder patients. 361 86
Five patients who had been diagnosed with panic disorder and
irritable bowel syndrome
are described. Both panic and gastrointestinal symptoms responded dramatically and rapidly to pharmacologic treatment of panic symptoms in all five patients. The frequent overlap of gastrointestinal symptoms and psychiatric (particularly anxiety) disorders suggests that some patients with functional gastrointestinal complaints may have a primary
anxiety disorder
.
...
PMID:Can panic disorder present as irritable bowel syndrome? 374 30
The author provides a psychological overview of the management and treatment of
irritable bowel syndrome
(
IBS
)
IBS
is a complex disorder and patients with
IBS
exhibit gastrointestinal symptoms,
anxiety disorders
, and mood disorders. Treatment alternatives are available.
...
PMID:Psychological aspects of irritable bowel syndrome. 811 62
Thirty-five patients with
irritable bowel syndrome
were referred from the gastroenterology service and underwent structured psychiatric interviews to assess the prevalence of psychiatric illness. Thirty-three (94%) of 35 patients were found to have a lifetime prevalence of any Axis I disorder; the predominant diagnoses were mood and
anxiety disorders
. Theoretical and practical implications of these findings are discussed.
...
PMID:Prevalence of psychiatric disorders in patients with irritable bowel syndrome. 849 4
1
2
3
4
5
6
7
Next >>