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Query: UMLS:C0021933 (intussusception)
 3,822 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

One hundred and thirteen specimens of Ileum received over the last 3 years (1990-92) were reviewed histologically and analysed to determine the aetiology of perforation. Perforations were seen in all age groups varying from one month to 75 years with a peak incidence during 3rd and 4th decades. Males were more frequently affected. Perforations were single or multiple involving the whole ileum. The highest incidence (52) was seen in enteric fever. Next in frequency (19) was tuberculosis. In 23 cases no specific aetiology could be identified. Other causes of perforation were injury and obstruction resulting from diverticulosis, intussusception adhesions and worms. A significantly high incidence (16.8%) of tuberculous perforation is noteworthy.
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PMID:Tuberculosis--an underestimated cause of ileal perforation. 935 50

Ascariasis is a common worm infestation in developing and under-developed countries. It is caused by the ingestion of food contaminated with Ascaris eggs from faeces and is more common in places with poor sanitation. Almost 25% of the world population is infested by Ascaris lumbricoides. Although ascariasis is a chronic disease, it can present as acute abdomen rarely. The wandering nature of Ascaris in and out of the bowel causes various abdominal complications such as intestinal obstruction, perforation, biliary ascariasis, pancreatic ascariasis, liver abscess, appendicitis, and Meckel's diverticulitis. Intestinal obstruction is the most common complication seen in children and is usually due to mechanical bowel obstruction, volvulus or intussusception. Mechanical obstruction by a bolus of worms is the most common cause of bowel obstruction. Perforation of bowel is rarely reported and it usually occurs in the diseased segment of bowel or following trauma. Perforation of an ileal volvulus secondary to ascariasis has been reported rarely. We present a 4-year-old boy who presented to the emergency room with features of bowel perforation and sepsis, after unsuccessful management for intestinal obstruction in another hospital. On laparotomy, the small bowel was teaming with Ascaris worms. Ileum showed a volvulus with closed loop obstruction and perforation. Peritoneal lavage with resection and ileostomy was done, which was closed at a later date. Anti-helminthic agents were started postoperatively and the boy recovered uneventfully.
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PMID:Ascaridial Volvulus: An Uncommon Cause of Ileal Perforation. 3004 14