Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0021933 (intussusception)
 3,822 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A retrospective study of sixty consecutive cases of proven intussusception with attempt at contrast enema reduction was performed to evaluate currently proposed contraindications to such reduction. When patient age, duration of symptoms, presence of small bowel obstruction and presence of a dissection sign were considered alone, none of the findings indicated irreducibility. Our overall reduction rate was 72% with a complication rate of 3%. This is similar to previously reported series and we concur with more recent publications that the only contraindications to non-surgical reduction of intussusception are free intraperitoneal air, peritonitis or evidence of infarcted bowel. Only when we encountered a combination of symptoms being present for greater than 48 hours and the presence of both small bowel obstruction and a dissection sign was reduction likely to be unsuccessful. However, the presence of a prognostic indicator occurring alone should not be considered a contraindication.
 ...
PMID:Significance of age, duration, obstruction and the dissection sign in intussusception. 239 63

Postoperative intussusception is a rare but serious complication which occurs usually during the early postoperative period with intermittent, but progressing intestinal obstruction with characteristic appearance of mucus-bloody stools. Two children with postoperative intussusception have been observed among 381 children who have had abdominal operations during the last three years (1985-1987) (0.5 per cent). Various postoperative complications developed in 45 children (11.8 per cent), in 2 of them (4.4 per cent) the complication being intussusception. Both children were operated for tumors. In one (1 1/2 years old) the postoperative intussusception was not diagnosed until it was re-operated; the child died. In the second child (3 months old) the postoperative intussusception was diagnosed by clinical and X-ray examination; the ileocolic portion of the intussusception was reduced by pneumocoloscopy, while the ileo-ileal required re-operation with manual reduction. The infant survived. Early diagnosis of this rare postoperative complication, especially when mucus-bloody stools appear and pneumocoloscopy is performed, is feasible. Appropriate treatment will help for a favourable outcome.
 ...
PMID:[Postoperative invagination in early childhood]. 239 76

For a period of 12 years (1977-1988) 64 children with Meckel's diverticulum (32 boys and 32 girls) have been operated. In early childhood (younger than 3 years) were 14.1 per cent; most of the others (59.4 per cent) were in school age. Complicated Meckel's diverticulum had 31.2 per cent of the children, the most common complication being intestinal obstruction--65 per cent (intussusception 25 per cent, strangulation 25 per cent and volvulus 15 per cent). Acute diverticulitis was found in 25 per cent of the complicated cases. In the clinical picture of these complications lacked cause-pathognomonic symptoms. The Meckel's diverticulum was removed in 60 children (93.8 per cent) the operation was cuneiform resection of the diverticulum in 96.6 per cent of the operated children. Only one child (1.7 per cent) had postoperative complication. All others were discharged from the clinic in full surgical repair. Practical inferences were made, based on analysis of the clinical case material.
 ...
PMID:[Meckel's diverticulum in childhood]. 239 87

To provide guidelines for the choice of treatment of intussusception, 10 factors that are known to be related to the outcome of treatment were studied in a series of 146 children with intussusception. The length of history, vomiting, rectal bleeding, small bowel obstruction, ileoileocolic intussusception, and the presence of a leading point were all significantly related to failure of hydrostatic reduction. Only 'rectal bleeding' and 'duration of symptoms of more than 48 hours' contributed significantly to the prediction of failure of hydrostatic reduction by logistic regression analysis. We believe that as well as the generally accepted contraindications--signs of peritonitis or bowel perforation--the presence of rectal bleeding when symptoms have lasted more than 48 hours is a contraindication to hydrostatic reduction.
 ...
PMID:Intussusception: factors related to treatment. 240 Feb 24

Melanoma is increasing in incidence. An often-unsuspected complication is metastasis to the gastrointestinal tract, which leads to bowel obstruction or intussusception. The most common symptoms in patients with gastrointestinal metastasis are vomiting, abdominal pain and abdominal distention. Metastatic disease should be suspected in any patient with gastrointestinal symptoms and a history of cutaneous melanoma.
 ...
PMID:Melanoma metastatic to the gastrointestinal tract. 240 21

Primary intestinal lymphomas (PIL) include a number of interesting clinical and pathological subtypes with distinct geographic, socioeconomic and age distribution patterns. This report describes clinical and pathologic features of 37 Iraqi children with PIL seen 1965-1983. Three distinct groups were recognized: Mediterranean lymphoma, 11 patients, characterized by diffuse involvement of the proximal bowel; commonly presents with abdominal pain, diarrhea and malabsorption; Burkitt's lymphoma, 13 patients, characterized by localized tumor in the distal ileum or ileocecal region; commonly presents with intussusception, abdominal tumor and pain, and Non-Burkitt's lymphoma, 13 patients, usually occurs as localized tumors in the distal ileum; commonly presents with abdominal tumor, pain and intestinal obstruction.
 ...
PMID:Primary intestinal lymphoma in Iraqi children. 242 21

Carcinoid of the small intestine, usually found in the terminal ileum, presents a diagnostic challenge when the classic clinical and laboratory findings are absent. The commonest symptom, marked abdominal pain due to intussusception, may arouse suspicion of carcinoid. The precise preoperative diagnosis in the absence of the classic syndrome is impossible and the only way to diagnose it is by colonoscopic biopsy of the terminal ileum. The case described illustrates such a preoperative diagnosis in a 59-year-old woman with severe abdominal pain, nausea, vomiting and weight loss. X-ray studies aroused suspicion of tumor intussusception as the cause of the intestinal obstruction. Colonoscopic biopsy revealed the presence of a carcinoid tumor. However, there had been no symptoms of the carcinoid syndrome, nor was there increased urinary 5-hydroxy indoleacetic acid. On operation the tumor was found to be disseminated and unresectable, so surgical intervention was limited to palliative ileo-transversostomy.
 ...
PMID:[Preoperative diagnosis of carcinoid of the terminal ileum in the absence of carcinoid syndrome]. 247 74

Nine hundred and four children with intestinal obstruction were studied. Necrotising enteritis was the commonest cause of intestinal obstruction in children. Acute intussusception was the second commonest cause in the whole group and the commonest cause in children under 1 year of age. Less common causes included band obstruction, sub acute intestinal obstruction and remnants of vitello-intestinal duct. A steady and significant improvement in the results of treatment was noted in children suffering from necrotising enteritis in the study period.
 ...
PMID:Acute intestinal obstruction. 258 2

Primary tumors of the small bowel are relatively rare. The 24 cases reported in this paper have been confirmed by operation and pathology. Based on clinical and radiologic findings and review of literature, the main X-ray manifestations of primary tumors of the small bowel were as follows: (1) Stenosis; (2) Filling defect; (3) Stiffness of involved intestinal wall with destruction of mucosa and loss of valvulae conniventes; (4) Intestinal obstruction or intussusception; (5) Dynamic dilatation and reversed peristalsis of the bowel segment proximal to the tumor. The causes of misdiagnosis and failure of detection and the site of predilection of the tumor were discussed. The differential points between benign and malignant tumors, sarcoma and carcinoma, metastatic tumor and primary tumor, Crohn's disease and carcinoma were mentioned.
 ...
PMID:[X-ray diagnosis of primary tumors of the small bowel (report of 24 cases)]. 262 18

The radiological diagnosis and interventional management of neuroendocrine tumours of the gastrointestinal tract and pancreas are challenging, demanding the complete gamut of available resources. Carcinoid tumours are most commonly found in the appendix and small bowel. Barium studies usually disclose a small solitary mucosal or submucosal mass in the distal ileum at times associated with smooth muscle hypertrophy and thickening of the mucosal folds. Intussusception and bowel obstruction may be the presenting finding. Mesenteric involvement may evoke a desmoplastic reaction with rigidity, fixation, angulation and tethering of small bowel loops. Angiography may demonstrate a hypervascular primary neoplasm but more frequently reveals vascular encasement and distortion from the mesenteric desmoplastic reaction. Pancreatic islet cell tumour is best defined radiologically by angiography and computed tomography as a well circumscribed hypervascular mass which enhances with contrast material. Portal venous sampling is of considerable assistance in localizing insulinoma. Metastases from neuroendocrine tumours to lymph nodes and to the liver are usually hypervascular. In the evaluation of the liver by CT scanning prior to contrast as well as dynamic scanning during the bolus intravenous injection of contrast material are necessary. At times the precontrast scan is more revealing. Computed tomography with the catheter in the superior mesenteric artery followed by selective hepatic arteriography is the most accurate combination for the detection of hepatic metastases. Interventional radiological management by sequential hepatic arterial embolization is the treatment of choice for multiple hepatic metastases from neuroendocrine tumours. Thus far, the maximum number of embolic episodes in a single patient has been 13. The carcinoid syndrome has been controlled in 87% while 79% of islet cell tumour hepatic metastases have responded. Contraindications to HAE includes a combination of all of the following: (i) replacement of more than 50% of the liver by tumour, (ii) serum lactic dehydrogenase above 425 mU/ml, (iii) serum glutamic oxaloacetic transaminase above 100 mU/ml, and (iv) bilirubin above 2 mg/dl. In the face of occlusion of the portal vein by intravascular neoplasm, HAE is contraindicated only if portal flow through collateral vein is away from the liver.
 ...
PMID:Gastrointestinal and pancreatic endocrine tumours. 267 21


<< Previous 1 2 3 4 5 6 7 8 9 10 Next >>