Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0021933 (intussusception)
 3,822 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Ninety-two patients with American Burkitt's lymphoma were studied retrospectively to elucidate the role of surgery in the complications of treatment of Burkitt's lymphoma. All of the patients reviewed had been treated with at least one chemotherapeutic agent. Seventy-five percent of the patients had predominantly abdominal disease that required a laparotomy for diagnosis and treatment when possible. The postoperative complications, such as infections, were not more frequent when compared with other elective surgical procedures. Ten percent of all the patients had episodes of significant gastrointestinal bleeding secondary to disease or to the chemotherapy. One patient was treated surgically, and two patients had fatal hemorrhages. Further abdominal complications that required surgery included intussusception, cholelithiasis, small bowel obstruction, and bowel perforation. The incidence of renal failure because of electrolyte imbalance from tumor lysis syndrome was 30%. One third of these patients required access for dialysis. Ten percent of patients developed hemorrhagic cystitis, but none required surgery. Surgery was necessary in five patients with life-threatening pericardial effusion. Other surgical treatments are also reviewed. It is concluded that Burkitt's lymphoma has a significant cure rate with the appropriate medical and surgical therapies, and that the surgical approach to the disease and its complication should be optimistic and appropriately aggressive.
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PMID:The role of surgery in the management of American Burkitt's lymphoma and its treatment. 709 57

Five cases of gastric infarction were observed in adolescent or adult cynomolgus monkeys (Macaca fascicularis) over a 20-month period. Gastric infarcts were encountered as striking and unexpected findings at necropsy. Gross and microscopic findings included gastric necrosis, hemorrhage, and edema that involved large areas of the fundus and pylorus. A consistent finding was the presence of thrombi in the gastric microvasculature, particularly in the venous system. All animals had acute clinical episodes with substantial tissue damage resulting from a variety of causes, including trauma, pancreatitis, necrotizing cystitis, and intestinal intussusception. In addition, three animals had microvascular thrombosis in nongastric tissues. Our findings suggest that cynomolgus monkeys may be predisposed to developing gastric infarction under conditions of severe systemic insult that predispose to disseminated intravascular coagulation.
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PMID:Gastric infarction in cynomolgus monkeys (Macaca fascicularis). 880 10

A 69-year-woman was admitted to the clinic in August 2018 because of general fatigue and low appetite.She had occult blood-positive and was referred to our hospital for further investigations.There was LST in the rectum for which colonoscopy and ESD were performed.She had abdominal pain and slight fever on postoperative day 1.Abdominal CT showed an intussusception in the ileum.We could not achieve endoscopic de-torsion and carried out laparotomy.The intussusception was found to be strangulated due to inflammatory polyp and mesenteric adhesion.The affected portion was resected.Although treatment for low hypoalbuminemia and neurogenic cystitis was required, she was discharged on postoperative day 28.
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PMID:[Intussusception Due to Inflammatory Polyp in the Ileum after ESD for Rectal LST]. 3163 Nov 57