Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0021933 (intussusception)
 3,822 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Four cases of Burkitt's lymphoma limited to the abdominal region are described. The sites of involvement included the duodenum, caecum, ascending colon, jejunum and ovaries. One case presented with an intussusception. The distribution of lesions in this series differs from the African cases described by Burkitt and from the small series reported from North America.
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PMID:The radiology of gastrointestinal Burkitt's lymphoma in children. 87 15

Studies of American Burkitt's lymphoma in 12 children showed a high incidence of abdominal involvement, including ileocecal masses with intussusception, retroperitoneal extension, and diffuse bowel involvement. Pleural effusions were common, and 2 patients had pulmonary nodules. Three patients had diffuse renal involvement. The mandibles and other bones were not affected in any of the 9 patients tested. The first 2 patients survived 0.5 to 8.5 months; the last 2 were treated much more aggressively and were still free of disease at the time this paper was written, 14 and 16 months after treatment, respectively. Hopefully, early recognition of the clinical and roentgenographic features of American Burkitt's lymphoma will contribute to improved survival.
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PMID:Roentgenographic features of American Burkitt's lymphoma. 88 71

The records of 28 children with the pathological diagnosis of American Burkitt's lymphoma were reviewed. Twenty-three of these children (82%) presented with primary abdominal tumors and 5 with disease located in the head and neck. Twelve required an emergency operation for either intestinal obstruction (3), intussusception (5), or appendicitis (4); the others underwent an elective exploration for tissue diagnosis. Ten patients had disease localized to one particular site. Seven of these 10 children underwent complete resection of the tumor including a right colectomy (4), small bowel segmental resection (1), tonsillectomy (1), and appendectomy (1). Eight children had a subtotal resection of the tumor (less than 90% of tumor burden) and the rest underwent incisional biopsies. Following the diagnosis, all patients received chemotherapy; 8 (29%) also were treated concurrently with radiation therapy. Nineteen patients (70%) remain long-term survivors with a mean survival time of 3.6 years. Eight patients died of either recurrent disease (6) or sepsis secondary to their chemotherapy, with a mean survival time of 6 months. Sixteen patients (57%) developed complications during their hospitalization that required surgical consultation or intervention (acute renal failure [9], pleural effusion [2], intestinal obstruction [5], gastric outlet obstruction [1], and wound infection [1]). No subsequent treatment of these complications resulted in mortality or morbidity. The significant positive determinant for survival was the initial absence of either bone marrow or central nervous system involvement (P less than .05). In those children who had complete resection of their tumor, survival time was greater than 3.7 years.(ABSTRACT TRUNCATED AT 250 WORDS)
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PMID:The role of surgery in American Burkitt's lymphoma in children. 177 35

During a 4-month period, high-resolution ultrasonography (US) was used to prospectively evaluate 70 children with clinically suspected acute appendicitis. Thirty-five US scans showed a noncompressible appendix with maximal outer diameters greater than 6 mm. This finding was considered positive for the diagnosis of acute appendicitis. Thirty-one of these 35 patients had acute appendicitis documented by surgical and pathologic findings. The remaining four patients were observed, and their symptoms resolved. Thirty-five patients had US scans considered negative for appendicitis. Seventeen of these patients had US findings positive for other conditions including mesenteric adenitis, ileitis, intussusception, Crohn disease, and Burkitt lymphoma. In this series US enabled diagnosis of acute appendicitis with a sensitivity of 94%, a specificity of 89%, and a predictive accuracy of 91%. Diagnosis of acute appendicitis can be made with US with the same accuracy in children as has been previously reported in series of adult patients. The use of US in clinically ambiguous cases may allow earlier diagnosis, prevention of perforation, and decreased complications in the pediatric patient with acute appendicitis.
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PMID:Acute appendicitis in children: evaluation with US. 219 94

Primary intestinal lymphomas (PIL) include a number of interesting clinical and pathological subtypes with distinct geographic, socioeconomic and age distribution patterns. This report describes clinical and pathologic features of 37 Iraqi children with PIL seen 1965-1983. Three distinct groups were recognized: Mediterranean lymphoma, 11 patients, characterized by diffuse involvement of the proximal bowel; commonly presents with abdominal pain, diarrhea and malabsorption; Burkitt's lymphoma, 13 patients, characterized by localized tumor in the distal ileum or ileocecal region; commonly presents with intussusception, abdominal tumor and pain, and Non-Burkitt's lymphoma, 13 patients, usually occurs as localized tumors in the distal ileum; commonly presents with abdominal tumor, pain and intestinal obstruction.
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PMID:Primary intestinal lymphoma in Iraqi children. 242 21

A four-year-old boy had a cecoanal intussusception prolapsing through the anus. A 4 x 4 cm cecal tumor served as the leading point of the intussusception. Laparotomy and histology revealed that the tumor was a solitary Burkitt's lymphoma of the cecum. Isolated Burkitt's lymphoma, as presented here, is rare, and such a combination has never been reported. Intussusception prolapsing through the anus and Burkitt's lymphoma are discussed, as well as a possible reason for the rarity of the condition.
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PMID:Burkitt's lymphoma protruding through the anus. Report of an unusual case. 340 88

Ninety-two patients with American Burkitt's lymphoma were studied retrospectively to elucidate the role of surgery in the complications of treatment of Burkitt's lymphoma. All of the patients reviewed had been treated with at least one chemotherapeutic agent. Seventy-five percent of the patients had predominantly abdominal disease that required a laparotomy for diagnosis and treatment when possible. The postoperative complications, such as infections, were not more frequent when compared with other elective surgical procedures. Ten percent of all the patients had episodes of significant gastrointestinal bleeding secondary to disease or to the chemotherapy. One patient was treated surgically, and two patients had fatal hemorrhages. Further abdominal complications that required surgery included intussusception, cholelithiasis, small bowel obstruction, and bowel perforation. The incidence of renal failure because of electrolyte imbalance from tumor lysis syndrome was 30%. One third of these patients required access for dialysis. Ten percent of patients developed hemorrhagic cystitis, but none required surgery. Surgery was necessary in five patients with life-threatening pericardial effusion. Other surgical treatments are also reviewed. It is concluded that Burkitt's lymphoma has a significant cure rate with the appropriate medical and surgical therapies, and that the surgical approach to the disease and its complication should be optimistic and appropriately aggressive.
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PMID:The role of surgery in the management of American Burkitt's lymphoma and its treatment. 709 57

To determine the place of surgery in the management of abdominal Burkitt's lymphoma, we retrospectively reviewed the records of 17 children treated over a period of 10 years (1983-1992). Patients were 14 males. Seven patients presented with acute abdominal pain, 6 with an abdominal mass and 5 with intestinal obstruction. In 3 cases, the diagnosis was made without laparotomy (2 percutaneous tumoral puncture, 1 pleural puncture). In the 14 other cases, the diagnosis was made by laparotomy with 3 biopsies and 11 resection of the tumor (7 complete and 4 incomplete). These laparotomies were complicated by 1 evisceration and 2 intestinal obstruction. At the end of the initial chemotherapy, 1 children was reoperated for a residual mass with no histological viable tumor. Sixteen children were long term survivors (14 > 2 years); 1 died. Surgery was indicated in cases of intestinal intussusception. In cases of abdominal mass, surgery could have been avoided twice (positive ascitic fluid). A complete tumoral resection had no influence on survival which depend of extra-abdominal extension and more over of response to chemotherapy.
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PMID:[Abdominal lymphomas in children: place of surgery]. 881 59

A 2-year-7-month old boy, presented with painless bloody stool was initially found to have an ulcerative, wide-based polyp in the ascending colon near the ileocecal region by colonoscopy. He received operation due to subsequent intussusception. Pathologic examination revealed an unusual case of polypoid Burkitt's lymphoma. The patient lives well 20 months later after receiving a standard chemotherapy. This case reminds us that colonic polyp and intussusception which is caused by Burkitt's lymphoma should be included in the differential diagnosis for a "wide-based polypoid" mass in the ascending colon.
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PMID:Burkitt's lymphoma with intussusception mimicking a colonic polyp. 894 34

Patients with systemic lupus erythematosus (SLE) are reported to have an increased risk of malignancy, especially lymphoproliferative disorders. We decribe the occurrence of ileocaecal intussusception secondary to Burkitt's lymphoma in a patient with SLE. A 23-year-old woman, who had been diagnosed with SLE 2 years ago, developed intermittent abdominal pain with a palpable mass. Computed tomography and a double-contrast barium enema showed a lobulated mass with intussusception at the ileocaecal junction. Right hemicolectomy and splenectomy was performed after histopathological examinations on colonoscopic biopsy revealed Burkitt's lymphoma. Fourteen months after chemotherapy, there is no evidence of recurrence of the Burkitt's lymphoma. When a patient with SLE has abdominal complaints, besides serositis, lupus enteritis such as peptic ulcer disease, mesenteric vasculitis with or without complications and pancreatitis, we have to consider intussusception secondary to gastrointestinal lymphoma as one of the differential diagnoses. Therefore, we should thoroughly investigate patients with SLE presenting with abdominal pain and not simply consider it afeature of lupus enteritis until other causes have been ruled out.
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PMID:Burkitt's lymphoma presenting as ileocaecal intussusception in systemic lupus erythematosus. 1120 54


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