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Query: UMLS:C0021843 (bowel obstruction)
 9,927 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The effects of interposing an antiperistaltic segment of colon between the jejunum and ileum after massive small bowel resection have been evaluated in rats. The intestinal transit time was prolonged, but fatal intestinal obstruction occurred in 2 of 12 rats. Albumin absorption was improved, but not triolein absorption, and the mean body weight 20 wk after resection was below that of rats subjected to massive resection alone. Morphological changes due to adaptation and intestinal obstruction were found after antiperistaltic colonic interposition. Antiperistaltic colonic interposition delays intestinal transit after massive small bowel resection in rats, but the effects are unpredictable, and may be detrimental.
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PMID:Antiperistaltic colonic interposition following massive small bowel resection in rats. 722 46

Clinical, anthropometric, hematologic, and biochemical variables, evaluated immediately before starting nutritional treatment, were related to survival in 76 terminal-cancer patients with irreversible bowel obstruction receiving home parenteral nutrition. At baseline, abnormally low values were observed in the following percentages of patients: 40.8% for body mass index, 59.2% for serum albumin, 84.2% for hemoglobin, 48.7% for lymphocyte count, and 60% for serum cholesterol. Survival on home parenteral nutrition ranged between 6 and 301 d, with a median of 74 d. Hemoglobin, serum albumin and serum cholesterol were lower in patients with a survival of less than 3 mo. With regard to Karnofsky performance status, median survival times were 63 d for a score below or equal to 50 and 128 d for a score between 60 and 70. Albumin and a Karnofsky score above 50 (but not age, weight, body mass index, lymphocyte count, or cholesterol) emerged (with a positive sign) as predictors of survival. In conclusion, terminal-cancer patients with irreversible bowel obstruction are often malnourished, showing a high prevalence of anemia and hypoalbuminemia. Survival differs widely and can be predicted only to a limited extent from initial values of serum albumin and Karnofsky performance status.
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PMID:Predictors of survival in terminal-cancer patients with irreversible bowel obstruction receiving home parenteral nutrition. 1144 97