Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0021843 (bowel obstruction)
 9,927 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Thirteen cases of diaphragmatic rupture following blunt trauma or gunshot wounds are presented. In 10 cases the diagnosis of diaphragmatic rupture was made immediately following the injury, and the defect was closed by primary diaphragmatic suture. In three cases, the diagnosis was delayed for 3 to 16 years after the initial trauma. In all of them, abdominal organs such as the colon or liver had migrated into the thoracic cavity. One of them had acute intestinal obstruction and died following several unsuccessful operations. The remaining two patients required plastic repair of the diaphragmatic hernia by a Dacron patch, and both recovered. The clinical and pathological aspects of diaphragmatic rupture, the importance of early diagnosis and surgical correction, and the surgical approach to this entity are considered. The use of Dacron fabric in delayed closure of diaphragmatic defects is described.
J Thorac Cardiovasc Surg 1977 Aug
PMID:Traumatic rupture of diaphragm: surgical reconstruction with special reference to delayed closure. 14 85

This report describes a symptomatic case of vena caval perforation caused by a vena cava filter. Functional small bowel obstruction due to vascular compromise was caused by a prong of the filter.
Cardiovasc Intervent Radiol
PMID:Late Greenfield filter vena cava perforation causing a small bowel obstruction: case report. 211 Dec 14

Transhiatal esophagectomy without thoracotomy has been performed in 65 adult patients with dysphagia from benign esophageal disease: strictures (30), neuromotor dysfunction (24), acute iatrogenic perforation (five), acute caustic injury (four), and recurrent gastroesophageal reflux (two). Nearly 70% (45) had undergone at least one prior esophageal operation, and 26% (17) had a history of between two and four esophageal operations. The esophagus was replaced with stomach in 53 patients (82%), colon being used only when there was a history of either prior gastric resection or caustic injury to the stomach (10 patients). Intraoperative blood loss averaged 1,050 ml. Intraoperative complications included pneumothorax in 38 patients (58%) and a tracheal laceration in one patient. Postoperative complications included transient recurrent laryngeal nerve paresis (11 patients, 17%), chylothorax (four patients, 6%), anastomotic leak (four patients, 6%), and small bowel obstruction (two patients). There were five hospital deaths (8% mortality), none related to the technique of esophagectomy. Follow-up ranges from 1 to 84 months (average 28 months). Of 46 patients with a cervical esophagogastric anastomosis in the original esophageal bed, 42 have had an excellent functional result although 17 have required at least one postoperative esophageal dilation. Two have developed true anastomotic strictures. Clinically significant gastroesophageal reflux has not occurred. Transhiatal esophagectomy for benign disease is feasible and safe, even after multiple previous esophageal operations. The stomach appears to be a better visceral esophageal substitute than colon, because it allows an initially easier technical operation and superior long-term functional results.
J Thorac Cardiovasc Surg 1985 Nov
PMID:Transhiatal esophagectomy for benign disease. 405 37

Current management of benign and malignant esophageal lesions has changed little in the past 25 years. Treatment of unresectable lesions has consisted primarily of exclusion and bypass procedures as well as prosthetic intubations for relief of dysphagia. A case of a Celestin tube fragmentation in a patient with unresectable esophageal carcinoma causing small bowel obstruction is presented. Diagnosis, management, and review of the literature are discussed. Recommendations for use of the Celestin tube in patients with good long-term prognoses include keeping a high index of suspicion for possible complications, close and regular radiographic and endoscopic follow-up, and early surgical intervention upon tube fragmentation.
J Thorac Cardiovasc Surg 1984 May
PMID:Fragmentation of a Celestin tube causing intestinal obstruction. Case report and review of the literature. 620 82

A singular case is described in which a pateint with a Celestin endoesophageal tube in place for 10 months died of complications from small bowel perforation resulting from disruption of the tube. The lower part of the tube lying within the stomach had deteriorated and become detached except for a single strand of nylon monofilament. This fragment passed into the small intestine, where it remained tethered at the level of the distal jejunum, acting first as an obscure cause of intermittent small bowel obstruction and later as the cause of jejunal perforation. In the patient who is a candidate for esophageal intubation and who has a life expectancy beyond 6 or 8 months, consideration should be given to using a device other than the Celestin tube. Whenever a Celestin appliance is used to palliate dysphagia, the intragastric part of the tube should be anchored to the stomach with multiple sutures.
J Thorac Cardiovasc Surg 1980 Jul
PMID:Fragmentation of Celestin tube: a cause of fatal intestinal perforation. 738 30

The literature on incarceration in Bochdalek hernias in adults is rather limited. Our purpose is to present two cases of this lesion that were treated surgically in the past ten years. The first patient, a 32 year old female was admitted in shock with an 8h history of left chest pain and dyspnoea. Chest X-ray showed a pleural effusion in the left hemithorax. Chest tube drainage revealed gastric fluid. We operated on her immediately, through a left thoracotomy, and found rupture of the stomach into the left pleural cavity. Strangulation of the fundus of the stomach due to congenital diaphragmatic hernia, Bochdalek's type, was found to be the cause of the rupture. We performed resection of the gangrenous segment of the stomach with primary closure. The second patient a 48 year old man was admitted with symptoms of large bowel obstruction. Per os gastrographin study showed the splenic flexure herniated into the left hemithorax. At the operation, through a paramedian left incision, the herniated large bowel was reduced back into the abdomen. In both cases the defect of the left hemidiaphragm was sutured with interrupted silk sutures. Both patients had an uneventful postoperative course. The diagnosis of Bochdalek hernia in the adult is usually made in case of complications, and that demands an immediate surgical repair.
J Cardiovasc Surg (Torino) 1994 Dec
PMID:Complications of congenital posterolateral diaphragmatic hernia in the adult. Report of two cases and literature review. 769 75

Transitional esophagectomy (THE) has been advocated as an alternative to the classic transthoracic approach. A variety of complications have been previously described with THE however, these can be avoided with meticulous detail to its technique. We report a patient who developed a complete small bowel obstruction secondary to a diaphragmatic hernia following transhiatal esophagectomy. Techniques to prevent such a rare complication is described.
Scand J Thorac Cardiovasc Surg 1996
PMID:Diaphragmatic hernia following transhiatal esophagectomy. 885 84

We evaluated the role of endothelin-B- (ET(B)) receptor-mediated action in the development and maintenance of deoxycorticosterone acetate (DOCA)-salt-induced hypertension, cardiovascular hypertrophy and renal damage, using the spotting lethal (sl) rat which carries a naturally occurring deletion in the ET(B)-receptor gene. Homozygous (sl/sl) rats exhibit abnormal development of the neural crest-derived epidermal melanocytes and the enteric nervous system (ENS), and do not live beyond 1 month because of intestinal aganglionosis and resulting intestinal obstruction. Therefore, the dopamine-beta-hydroxylase (D betaH) promoter was used to direct ET(B) transgene expression in sl/sl rats to support normal ENS development. D betaH-ET(B) sl/sl rats live into adulthood and are healthy, expressing ET(B)-receptor in adrenals and other adrenergic neurons. When homozygous (sl/sl) and wild-type (WT) (+/+) rats, all of which were transgenic, were treated with DOCA and salt for 4 weeks, the homozygous rats exhibited significantly earlier and higher increases in systolic blood pressure than WT rats. The daily oral administration of ABT-627, a selective ET(A)-receptor antagonist, almost completely suppressed the DOCA-salt-induced hypertension in both groups. Renal dysfunction and histological damage induced by DOCA-salt treatment were more severe in homozygous than in WT rats. Increased and marked vascular hypertrophy of the aorta was also observed in homozygous rats, compared with WT rats. Renal and vascular injuries induced by DOCA and salt were significantly improved by ABT-627 administration. We propose that ET(B)-receptor-mediated actions are protective factors in the pathogenesis of DOCA-salt-induced hypertension. ET(A)-mediated actions are at least partly responsible for the increased susceptibility to DOCA-salt-induced hypertension and related tissue injuries in ET(B)-receptor-deficient rats.
J Cardiovasc Pharmacol 2000 Nov
PMID:Increased susceptibility to deoxycorticosterone acetate-salt-induced hypertension in endothelin-B-receptor-deficient rats. 1107 44

A patient who had undergone gastric resection for carcinoma, had closed loop obstruction of the duodenum due to neoplasia at the duodenojejunal junction. The obstruction was relieved successfully by transhepatic placement of a duodenojejunal stent. We were compelled to use the transhepatic route because a Roux-Y reconstruction had been performed. Transhepatic placement may be the only chance of palliation in a small subset of patients with malignant intestinal obstruction.
Cardiovasc Intervent Radiol
PMID:The transhepatic route for the placement of a duodenojejunal stent: application in a postoperative closed loop obstruction of the duodenum. 1117 19

Intestinal stricture from superior mesenteric vein (SMV) thrombosis is a relatively infrequent, though important cause of intestinal obstruction. The symptom of intestinal obstruction in a patient with chronic SMV thrombosis should be considered as the possibility of bowel stricture. We report 2 cases of small bowel stricture that is related to chronic SMV thrombosis which were treated with segmental resection of strictured bowel.
J Cardiovasc Surg (Torino) 2002 Dec
PMID:Superior mesenteric thrombosis associated with small bowel stricture. Case report. 1248 87


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