Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0021390 (
inflammatory bowel disease
)
23,302
document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
gut
2848
IBD
1729
cytokine
1660
Sep
1462
TNF
1196
tumor necrosis factor
954
Mol
738
IL-6
673
IL-10
665
myeloperoxidase
575
CD4
533
IL-17
424
lymphoid
365
TNF-alpha
318
ankylosing spondylitis
311
IFN
278
lipopolysaccharide
270
IL-8
260
interferon
256
DSS
249
NOD2
247
IL-23
242
inducible nitric oxide synthase
227
ASA
222
IgA
221
IL-4
217
chemokine
209
C-reactive protein
207
IFN-gamma
188
TLR4
174
LPS
167
CD8
157
interleukin-6
154
IL-1
152
collagen
151
IL-2
150
Cytokine
148
tumor necrosis factor alpha
148
STAT3
147
HLA
141
interleukin-10
137
She
133
p65
130
HLA-B27
125
interferon-gamma
125
insulin
122
CARD15
117
COX-2
116
mucin
115
p38
114
IL-22
109
granulocyte
109
endoplasmic reticulum
106
cyclooxygenase-2
106
CD25
106
MAPK
103
albumin
100
Tumor necrosis factor
100
occludin
94
IL-18
92
hemoglobin
91
p53
88
IL-13
88
alkaline phosphatase
87
adhesion molecule
87
MRI
87
ICAM-1
84
superoxide dismutase
84
mast cell
83
nitric oxide synthase
81
caspase-3
77
NLRP3
76
lactoferrin
75
glycoprotein
75
cyclooxygenase
73
B27
72
TLR2
71
serum albumin
70
substance P
70
IL10
69
more...
Disease
inflammatory bowel disease
23302
Crohn's disease
6899
ulcerative colitis
6478
colitis
4575
irritable bowel syndrome
2299
cancer
2035
rheumatoid arthritis
1136
colorectal cancer
1089
tumor
740
arthritis
662
psoriasis
608
Colitis
555
primary sclerosing cholangitis
491
diabetes
482
colon cancer
467
celiac disease
458
dysplasia
446
multiple sclerosis
443
obesity
440
asthma
431
Inflammatory Bowel Disease
392
enteropathy
385
carcinoma
375
ankylosing spondylitis
343
systemic lupus erythematosus
332
anemia
287
carcinogenesis
270
depression
261
autoimmune disease
260
pyoderma gangrenosum
250
DSS
249
DSS
249
infectious diseases
239
sepsis
239
malnutrition
237
liver disease
232
sepsis
229
psoriatic arthritis
223
vasculitis
214
lymphoma
212
tuberculosis
212
Colon
210
Colon
210
Colon
210
malabsorption
200
tumorigenesis
194
atherosclerosis
192
gastrointestinal disease
191
hepatitis
191
chronic disease
189
osteoporosis
187
cirrhosis
184
pancreatitis
181
immunodeficiency
180
Crohn's colitis
177
adenocarcinoma
176
cholangitis
169
skin disease
168
ileitis
165
uveitis
150
HIV
149
ischemia
148
cytomegalovirus
144
diverticular disease
142
cardiovascular disease
140
diverticulitis
139
type 1 diabetes
136
adenoma
132
Mycobacterium
130
Clostridium difficile infection
127
enteritis
126
HLA-B27
125
bowel obstruction
123
enterocolitis
122
Best
119
metabolic syndrome
119
cystic fibrosis
105
sarcoidosis
103
proctitis
100
type 2 diabetes
100
more...
Symptom
diarrhea
1321
abdominal pain
516
pain
417
vomiting
130
fatigue
124
constipation
104
nausea
85
anorexia
69
arthralgia
52
erythema
49
headache
48
discomfort
45
discomfort
44
anesthesia
43
back pain
42
splenomegaly
39
bloating
38
seizures
36
chest pain
33
weakness
30
Ill
28
colic
28
dyspnea
27
cough
26
stigma
25
intestinal bleeding
25
acute abdomen
23
cachexia
22
low back pain
22
hepatomegaly
22
Gastrointestinal symptoms
20
abdominal discomfort
20
microbial colonization
20
chronic constipation
19
Wind
19
overweight
19
nausea and vomiting
18
respiratory distress
17
fever of unknown origin
16
tenesmus
16
analgesia
15
lethargy
15
collapse
15
myalgia
15
clubbing
12
shortness of breath
11
acute abdominal pain
11
alexithymia
11
dizziness
10
hepatosplenomegaly
10
epigastric pain
9
pelvic pain
9
ataxia
9
starvation
9
Chronic abdominal pain
8
thinning
8
flushing
8
Visceral pain
8
sore throat
7
decreased appetite
7
abdominal cramps
7
acute stress
7
dry eye
6
chronic cough
6
productive cough
6
heartburn
6
chills
6
acute pain
6
hypoproteinemia
5
hypothermia
5
rectal pain
5
Musculoskeletal symptoms
5
right lower quadrant pain
5
chronic back pain
5
exertional dyspnea
5
insomnia
5
blurred vision
5
pneumaturia
5
anal pain
5
sleepiness
5
more...
Drug
Dermatol
219
Infliximab
193
Infliximab
193
IFN-gamma
179
IL-2
152
Bifidobacterium
111
Mesalazine
67
CSF
55
Budesonide
46
Adalimumab
38
ROS
37
lysine
35
lactose
34
Sulphasalazine
29
Monit
28
IL-11
26
ascorbate
26
Dextran sulfate sodium
25
Prednisolone
23
Retinoic acid
22
Asthma
22
G-CSF
21
Rifaximin
18
Natalizumab
17
Tacrolimus
15
Dial
15
p75
14
Cardiovasc
14
CDP
13
Isotretinoin
13
Indomethacin
13
vitamin E
13
MAP
13
Histamine
12
ROC
12
Copaxone
11
CCL
11
Leaf
10
IL-1ra
10
niacin
9
Portal
8
GEO
8
Gastro
8
EPA
8
ampicillin
8
caffeine
7
Asn
7
Prednisone
7
Dipentum
7
Heme
7
CAM
7
Rituximab
7
Vitamin B
6
Mirtazapine
6
NADH
6
TAK
6
Glucagon
6
Bromelain
6
Nitric Oxide
6
Mercaptopurine
6
Glutathione
6
PMPA
5
Vitamin B12
5
CED
5
Hypaque
5
Hypaque
5
Vitamin E
5
Methylprednisolone
5
ICI
5
DNase I
5
Golimumab
5
Gel
5
Doxycycline
5
Paraffin
5
Ketotifen
4
ENT
4
THF
4
ABC
4
ALA
4
ACT
4
more...
Enzyme
peroxidase
602
mitogen-activated protein kinase
243
ERK
111
superoxide dismutase
97
thiopurine methyltransferase
88
alkaline phosphatase
87
focal adhesion kinase
82
APC
71
catalase
67
caspase-3
63
luciferase
56
caspase-1
55
protein kinase
52
NO synthase
51
NADPH oxidase
50
lysozyme
48
trypsin
45
NADPH oxidase
45
protein kinase C
40
P-glycoprotein
40
reverse transcriptase
35
calcineurin
34
MIP
33
collagenase
33
myosin light chain kinase
30
lipoxygenase
29
NOS
29
alanine aminotransferase
29
IKK
28
glutathione peroxidase
28
thrombin
26
ATPase
26
ACS
26
transglutaminase
25
proteasome
24
MEK
23
tryptase
22
phospholipase A2
22
elastase
21
phosphodiesterase
21
caspase-8
20
AMP-activated protein kinase
20
lactate dehydrogenase
18
lactase
18
aspartate aminotransferase
18
meprin
17
glutathione S-transferase
16
MMP
16
neutrophil elastase
15
kallikrein
15
CYP3A4
14
phospholipase C
14
MMP-3
14
xanthine oxidase
14
phosphatidylinositol 3-kinase
14
guanylate cyclase
14
arginase
14
PARP
14
gamma-glutamyl transpeptidase
13
MAP
13
sucrase
13
ACE
13
cathepsin G
11
caspase-9
11
BBE
10
dipeptidyl peptidase IV
10
TACE
10
granzyme B
10
lipase
10
heme oxygenase
10
CD10
9
chitinase
9
AMPK
9
AMPK
9
urease
9
sphingosine kinase
9
RNA polymerase
9
prolyl hydroxylase
9
thromboplastin
9
urease
9
more...
Compound
Clin
2413
Dec
1515
sodium
1493
sulfate
1236
TNF
1196
DNA
616
water
538
oxygen
417
DSS
252
calcium
243
nitric oxide
237
ASA
234
iron
226
vitamin D
211
barium
160
phosphate
159
ethanol
142
glucose
128
acetate
128
acetic acid
126
Sulfasalazine
102
Azathioprine
100
zinc
97
nitrogen
86
arginine
79
leucine
66
hydrogen
66
ATP
63
Vitamin D
61
salt
61
serine
60
His
59
tyrosine
58
ANCA
58
Mesalamine
57
PGE2
56
GSH
56
tryptophan
56
GSH
56
tryptophan
54
retinoic acid
54
tryptophan
52
tryptophan
52
galactose
51
creatinine
45
glutamine
45
5-HT
45
THP
45
Methotrexate
45
Dextran
44
THP
44
Phe
42
cysteine
41
butyric acid
39
PEG
38
PGE
38
lysine
37
potassium
37
6-Mercaptopurine
37
Curcumin
36
nitrate
35
salicylic acid
34
homocysteine
31
Cyclosporine
30
alanine
30
methionine
30
cAMP
29
CO2
29
selenium
28
copper
28
sulfuric acid
27
threonine
27
Ursodeoxycholic acid
27
ACS
26
ACS
26
H2S
25
Sodium
25
EDTA
24
EDTA
24
nicotinamide
24
more...