Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0021390 (inflammatory bowel disease)
23,302 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
gut 2848
IBD 1729
cytokine 1660
Sep 1462
TNF 1196
tumor necrosis factor 954
Mol 738
IL-6 673
IL-10 665
myeloperoxidase 575
CD4 533
IL-17 424
lymphoid 365
TNF-alpha 318
ankylosing spondylitis 311
IFN 278
lipopolysaccharide 270
IL-8 260
interferon 256
DSS 249
NOD2 247
IL-23 242
inducible nitric oxide synthase 227
ASA 222
IgA 221
IL-4 217
chemokine 209
C-reactive protein 207
IFN-gamma 188
TLR4 174
LPS 167
CD8 157
interleukin-6 154
IL-1 152
collagen 151
IL-2 150
Cytokine 148
tumor necrosis factor alpha 148
STAT3 147
HLA 141
interleukin-10 137
She 133
p65 130
HLA-B27 125
interferon-gamma 125
insulin 122
CARD15 117
COX-2 116
mucin 115
p38 114
IL-22 109
granulocyte 109
endoplasmic reticulum 106
cyclooxygenase-2 106
CD25 106
MAPK 103
albumin 100
Tumor necrosis factor 100
occludin 94
IL-18 92
hemoglobin 91
p53 88
IL-13 88
alkaline phosphatase 87
adhesion molecule 87
MRI 87
ICAM-1 84
superoxide dismutase 84
mast cell 83
nitric oxide synthase 81
caspase-3 77
NLRP3 76
lactoferrin 75
glycoprotein 75
cyclooxygenase 73
B27 72
TLR2 71
serum albumin 70
substance P 70
IL10 69
more...
Disease
inflammatory bowel disease 23302
Crohn's disease 6899
ulcerative colitis 6478
colitis 4575
irritable bowel syndrome 2299
cancer 2035
rheumatoid arthritis 1136
colorectal cancer 1089
tumor 740
arthritis 662
psoriasis 608
Colitis 555
primary sclerosing cholangitis 491
diabetes 482
colon cancer 467
celiac disease 458
dysplasia 446
multiple sclerosis 443
obesity 440
asthma 431
Inflammatory Bowel Disease 392
enteropathy 385
carcinoma 375
ankylosing spondylitis 343
systemic lupus erythematosus 332
anemia 287
carcinogenesis 270
depression 261
autoimmune disease 260
pyoderma gangrenosum 250
DSS 249
DSS 249
infectious diseases 239
sepsis 239
malnutrition 237
liver disease 232
sepsis 229
psoriatic arthritis 223
vasculitis 214
lymphoma 212
tuberculosis 212
Colon 210
Colon 210
Colon 210
malabsorption 200
tumorigenesis 194
atherosclerosis 192
gastrointestinal disease 191
hepatitis 191
chronic disease 189
osteoporosis 187
cirrhosis 184
pancreatitis 181
immunodeficiency 180
Crohn's colitis 177
adenocarcinoma 176
cholangitis 169
skin disease 168
ileitis 165
uveitis 150
HIV 149
ischemia 148
cytomegalovirus 144
diverticular disease 142
cardiovascular disease 140
diverticulitis 139
type 1 diabetes 136
adenoma 132
Mycobacterium 130
Clostridium difficile infection 127
enteritis 126
HLA-B27 125
bowel obstruction 123
enterocolitis 122
Best 119
metabolic syndrome 119
cystic fibrosis 105
sarcoidosis 103
proctitis 100
type 2 diabetes 100
more...
Symptom
diarrhea 1321
abdominal pain 516
pain 417
vomiting 130
fatigue 124
constipation 104
nausea 85
anorexia 69
arthralgia 52
erythema 49
headache 48
discomfort 45
discomfort 44
anesthesia 43
back pain 42
splenomegaly 39
bloating 38
seizures 36
chest pain 33
weakness 30
Ill 28
colic 28
dyspnea 27
cough 26
stigma 25
intestinal bleeding 25
acute abdomen 23
cachexia 22
low back pain 22
hepatomegaly 22
Gastrointestinal symptoms 20
abdominal discomfort 20
microbial colonization 20
chronic constipation 19
Wind 19
overweight 19
nausea and vomiting 18
respiratory distress 17
fever of unknown origin 16
tenesmus 16
analgesia 15
lethargy 15
collapse 15
myalgia 15
clubbing 12
shortness of breath 11
acute abdominal pain 11
alexithymia 11
dizziness 10
hepatosplenomegaly 10
epigastric pain 9
pelvic pain 9
ataxia 9
starvation 9
Chronic abdominal pain 8
thinning 8
flushing 8
Visceral pain 8
sore throat 7
decreased appetite 7
abdominal cramps 7
acute stress 7
dry eye 6
chronic cough 6
productive cough 6
heartburn 6
chills 6
acute pain 6
hypoproteinemia 5
hypothermia 5
rectal pain 5
Musculoskeletal symptoms 5
right lower quadrant pain 5
chronic back pain 5
exertional dyspnea 5
insomnia 5
blurred vision 5
pneumaturia 5
anal pain 5
sleepiness 5
more...
Drug
Dermatol 219
Infliximab 193
Infliximab 193
IFN-gamma 179
IL-2 152
Bifidobacterium 111
Mesalazine 67
CSF 55
Budesonide 46
Adalimumab 38
ROS 37
lysine 35
lactose 34
Sulphasalazine 29
Monit 28
IL-11 26
ascorbate 26
Dextran sulfate sodium 25
Prednisolone 23
Retinoic acid 22
Asthma 22
G-CSF 21
Rifaximin 18
Natalizumab 17
Tacrolimus 15
Dial 15
p75 14
Cardiovasc 14
CDP 13
Isotretinoin 13
Indomethacin 13
vitamin E 13
MAP 13
Histamine 12
ROC 12
Copaxone 11
CCL 11
Leaf 10
IL-1ra 10
niacin 9
Portal 8
GEO 8
Gastro 8
EPA 8
ampicillin 8
caffeine 7
Asn 7
Prednisone 7
Dipentum 7
Heme 7
CAM 7
Rituximab 7
Vitamin B 6
Mirtazapine 6
NADH 6
TAK 6
Glucagon 6
Bromelain 6
Nitric Oxide 6
Mercaptopurine 6
Glutathione 6
PMPA 5
Vitamin B12 5
CED 5
Hypaque 5
Hypaque 5
Vitamin E 5
Methylprednisolone 5
ICI 5
DNase I 5
Golimumab 5
Gel 5
Doxycycline 5
Paraffin 5
Ketotifen 4
ENT 4
THF 4
ABC 4
ALA 4
ACT 4
more...
Enzyme
peroxidase 602
mitogen-activated protein kinase 243
ERK 111
superoxide dismutase 97
thiopurine methyltransferase 88
alkaline phosphatase 87
focal adhesion kinase 82
APC 71
catalase 67
caspase-3 63
luciferase 56
caspase-1 55
protein kinase 52
NO synthase 51
NADPH oxidase 50
lysozyme 48
trypsin 45
NADPH oxidase 45
protein kinase C 40
P-glycoprotein 40
reverse transcriptase 35
calcineurin 34
MIP 33
collagenase 33
myosin light chain kinase 30
lipoxygenase 29
NOS 29
alanine aminotransferase 29
IKK 28
glutathione peroxidase 28
thrombin 26
ATPase 26
ACS 26
transglutaminase 25
proteasome 24
MEK 23
tryptase 22
phospholipase A2 22
elastase 21
phosphodiesterase 21
caspase-8 20
AMP-activated protein kinase 20
lactate dehydrogenase 18
lactase 18
aspartate aminotransferase 18
meprin 17
glutathione S-transferase 16
MMP 16
neutrophil elastase 15
kallikrein 15
CYP3A4 14
phospholipase C 14
MMP-3 14
xanthine oxidase 14
phosphatidylinositol 3-kinase 14
guanylate cyclase 14
arginase 14
PARP 14
gamma-glutamyl transpeptidase 13
MAP 13
sucrase 13
ACE 13
cathepsin G 11
caspase-9 11
BBE 10
dipeptidyl peptidase IV 10
TACE 10
granzyme B 10
lipase 10
heme oxygenase 10
CD10 9
chitinase 9
AMPK 9
AMPK 9
urease 9
sphingosine kinase 9
RNA polymerase 9
prolyl hydroxylase 9
thromboplastin 9
urease 9
more...
Compound
Clin 2413
Dec 1515
sodium 1493
sulfate 1236
TNF 1196
DNA 616
water 538
oxygen 417
DSS 252
calcium 243
nitric oxide 237
ASA 234
iron 226
vitamin D 211
barium 160
phosphate 159
ethanol 142
glucose 128
acetate 128
acetic acid 126
Sulfasalazine 102
Azathioprine 100
zinc 97
nitrogen 86
arginine 79
leucine 66
hydrogen 66
ATP 63
Vitamin D 61
salt 61
serine 60
His 59
tyrosine 58
ANCA 58
Mesalamine 57
PGE2 56
GSH 56
tryptophan 56
GSH 56
tryptophan 54
retinoic acid 54
tryptophan 52
tryptophan 52
galactose 51
creatinine 45
glutamine 45
5-HT 45
THP 45
Methotrexate 45
Dextran 44
THP 44
Phe 42
cysteine 41
butyric acid 39
PEG 38
PGE 38
lysine 37
potassium 37
6-Mercaptopurine 37
Curcumin 36
nitrate 35
salicylic acid 34
homocysteine 31
Cyclosporine 30
alanine 30
methionine 30
cAMP 29
CO2 29
selenium 28
copper 28
sulfuric acid 27
threonine 27
Ursodeoxycholic acid 27
ACS 26
ACS 26
H2S 25
Sodium 25
EDTA 24
EDTA 24
nicotinamide 24
more...