Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0021359 (infertility)
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Human Gene/Protein
Sperm mitochondria-associated cysteine-rich protein 10.3
inhibitor of growth family, member 2 10.3
chromosome 4 open reading frame 37 10.3
centromere protein T 10.3
Bromodomain and WD repeat domain containing 1 10.3
Testis-specific serine kinase 3 10.3
ubiquitously transcribed tetratricopeptide repeat gene, Y-linked 10.3
RNF220 protein 10.3
TLE6 protein 10.3
zona pellucida glycoprotein B 10.3
C16orf55 10.3
Sperm-associated antigen 1 10.3
nuclear RNA export factor 2 10.3
protocadherin beta 9 10.3
TCP11 protein 10.3
zinc finger protein 778 10.3
tyrosylprotein sulfotransferase-2 10.3
FAM47C 10.3
DEFB112 10.3
zona pellucida glycoprotein 1 10.3
LYPD4 protein 10.3
LOC100130539 10.3
hypothetical protein FLJ32704 10.3
PMFBP1 9.8
KIF19A 9.7
dpy-19-like 2 9.7
SIX6OS1 9.7
BS-17 9.7
prion-like protein doppel 9.3
GOLGA2LY 9.3
BRDT protein 9.3
REXO4 9.3
POLR3H 9.3
TLE6 9.3
eukaryotic translation initiation factor 1A, Y-linked 9.3
SPATA6 9.3
Variable charge, X-linked 9.3
MRPL20 9.3
CEBPB protein 9.3
DEFB124 9.3
SPAG11A 9.3
NSUN7 9.3
RNASE9 9.3
PCDP1 9.3
TUBB8 9.3
nuclear localized factor 2 9.3
meiosis defective 1 9.3
OLFML1 9.3
CRISP2 protein 9.3
LRRC56 9.3
synaptonemal complex central element protein 1 9.3
SPTRX3 9.0
TXNDC8 8.9
POF1B 8.8
SYCE1 8.7
SPOCD1 8.7
TSGA2 8.7
ADAM18 8.7
coiled-coil domain containing 42 8.7
AURKC protein 8.7
RBM43 8.7
HEATR2 8.7
CEP78 8.7
DEFB125 8.7
RNase 9 8.7
NIMA-related kinase 1 8.7
DEFB127 8.7
ADD1 protein 8.7
BTG4 protein 8.7
ZP1 protein 8.7
ACTL7A 8.7
CSTF2T 8.7
RIM-BP3 8.7
spermatogenesis associated 22 8.7
aurora kinase C 8.6
ARMC4 8.4
DPY19L2 8.4
SPACA1 8.4
TSSK2 8.3
AZF 8.3
more...
Disease
ODG2 10.3
Uterine synechiae 10.3
Ovarian Cysts 10.3
infertility 10.3
Extraovarian endometriosis 10.3
VSPA 10.3
Calcium abnormality 10.3
Chronic endocervicitis 10.3
Tubo-ovarian adhesions 10.3
male urogenital infection 10.3
Fallopian tube infection 10.3
Chlamydial endometritis 10.3
Disorder of androgen receptor 10.3
nonovulation 10.3
Luteinized unruptured follicle syndrome 10.3
Pelvic peritoneal adhesions 10.3
Testicular tumor of adrenogenital syndrome 10.3
Iatrogenic ovarian failure 10.3
Primary infertility 10.1
Anovulatory infertility 10.1
Salpingitis isthmica nodosa 10.0
Fallopian tube obstruction 9.9
Genital tuberculosis 9.4
Empty follicle syndrome 9.4
Autoimmune orchitis 9.3
BRKS1 9.3
Resistant ovary syndrome 9.3
Tuberculous endometritis 9.3
dysfunction; endometrial 9.3
Primary ovarian failure 9.3
Tritrichomonosis 9.3
Urovagina 9.3
Pelvic adhesions 9.3
20,22-desmolase deficiency 9.3
Intrauterine adhesions 9.1
sexual dysfunction and infertility 8.9
necrospermia 8.9
pelvic adhesions 8.8
Asherman's syndrome 8.7
Late onset congenital adrenal hyperplasia 8.7
Twirling 8.7
Central hypogonadism 8.7
Bovine genital campylobacteriosis 8.7
Chronic epididymitis 8.7
Sex differentiation disorders 8.7
DFNB32 8.7
Rumen impaction 8.7
Moon's molars 8.7
male infertility 8.6
Pelvic inflammatory disease 8.5
Subfertility 8.4
Chronic endometritis 8.3
hydrosalpinx 8.3
anovulation 8.3
Pelvic endometriosis 8.3
oligospermia 8.3
fimbrial cyst 8.3
Chronic cervicitis 8.3
Ovarian Insufficiency 8.3
Tubo-ovarian abscess 8.3
Teratospermia 8.3
uterine cyst 8.3
endometrial dysplasia 8.3
Pelvic abscess 8.3
Chronic PID 8.3
trisomy Xq 8.3
Recurrent bronchitis 8.3
TB salpingitis 8.3
cervical chlamydia 8.3
Male accessory gland infection 8.3
varicocele 8.2
azoospermia 8.2
retrograde menstruation 8.2
ovarian dysfunction 8.1
Hypothalamic amenorrhea 8.1
Undescended testis 8.0
acrorenal syndrome 7.9
Pleural endometriosis 7.9
Freemartinism 7.9
Papillary cystadenoma 7.9
more...
Symptom
female fertility problem 10.3
dry vulva 10.3
PELVIC PAIN 10.3
Fear symptoms 9.3
menstrual pelvic pain 9.3
unable to conceive 9.0
male subfertility 8.6
pelvic pain 7.8
Increased libido 7.8
intermenstrual pain 7.6
Male sexual dysfunction 7.6
Hemorrhagic ascites 7.3
absent menses 6.9
false labor 6.7
menometrorrhagia 6.6
Pituitary enlargement 6.3
dyschezia 6.3
reproductive problem 6.1
hematocolpos 6.1
Vaginal dryness 6.1
cracked lips 6.1
out of breath 6.1
testicular pain 6.0
vaginal discomfort 5.8
urethral discharge 5.7
Lower abdominal pain 5.7
difficulty with urination 5.5
Mild pain 5.4
urological problem 5.4
testicular lump 5.4
abnormal taste 5.3
strangury 5.2
masculinization 5.0
irregular bleeding 5.0
Chronic pelvic pain 5.0
dry throat 4.9
male puberty 4.8
Visual symptoms 4.4
Pain symptoms 4.4
Chronic abdominal pain 4.4
female puberty 4.3
eye discharge 4.2
menopausal symptoms 4.2
hot flushes 4.1
Urinary symptoms 4.0
mastalgia 4.0
iliac fossa pain 4.0
Physical findings 3.9
anosmia 3.8
Spotting 3.8
peri-menopausal 3.8
hot flashes 3.7
hearing voices 3.6
dysuria 3.6
pedal edema 3.5
No adverse effect 3.5
infant diarrhea 3.5
hyperemesis gravidarum 3.5
urinary frequency 3.4
Visual disturbances 3.4
vestibulitis 3.2
acute abdominal pain 3.2
microbial colonization 3.2
chromosome marker 3.1
physical appearance 3.0
abdominal pain 3.0
Severe pain 2.9
Psychiatric symptoms 2.9
physical exhaustion 2.9
overweight 2.9
stomach pain 2.9
stigma 2.8
intention tremor 2.8
POA 2.8
Spastic 2.8
Decreased activity 2.8
abdominal discomfort 2.7
catarrh 2.7
Spots 2.4
disturbed balance 2.4
more...
Drug
Alevaire 8.7
Clomiphene citrate 8.4
Nicotine bitartrate 8.3
Bravelle 8.1
Humegon 7.9
Gonal-F 7.8
Menotropins 7.8
Gonal-F 7.6
Follistim 7.3
Ganirelix 7.2
Buserelin acetate 7.1
Cetrotide 7.0
Lutropin alfa 6.6
Parlodel 6.4
Serum gonadotrophin 6.3
Gestrinone 6.3
C.M.C. 6.3
OP-2 6.2
cetrorelix acetate 6.2
Parlodel 6.1
Myo-Inositol 5.9
Mircette 5.9
Luteinizing 5.7
Triptorelin 5.6
Dienogest 5.6
Oxyphenbutazone 5.6
Tuareg 5.6
Icodextrin 5.5
Bucrylate 5.5
Actos 5.4
HCG 5.4
Femara 5.3
Folic Acid 5.3
FSH-beta 5.3
Cetrorelix 5.2
FSH-beta 5.2
Pregnyl 5.2
Diprolene 5.1
Andriol 5.1
Actos 5.0
Depo-Provera 5.0
Norplant 5.0
Lupron 4.9
Estrumate 4.9
Swainsonine 4.9
Altrenogest 4.9
Tarivid 4.8
Paraplatin 4.7
Avandia 4.7
Astragali radix 4.7
Glybenclamide 4.6
Sulphasalazine 4.6
Creosote 4.6
DDF 4.6
FSH-beta 4.6
Zaditen 4.4
Norplant 4.4
Levonorgestrel 4.3
Lumefantrine 4.3
TES 4.1
Fosamax 4.1
Sonata 4.1
Velban 4.0
Vibramycin 4.0
Hakka 4.0
2-Methoxyestradiol 3.9
Estrogens 3.8
Midodrine 3.7
Polydioxanone 3.7
Ovulen 3.7
Malonaldehyde 3.6
Fipronil 3.6
Zoladex 3.5
Anafranil 3.5
Finasteride 3.5
Estriol 3.5
Lutalyse 3.3
Tenoxicam 3.3
Antithymocyte globulin 3.3
Zoladex 3.2
more...
Enzyme
proprotein convertase 5 7.4
EC 3.1.1.47 6.6
acrosin 5.9
BCKDH 5.7
25-hydroxyvitamin D3 1alpha-hydroxylase 5.6
SOAT 5.2
acyloxyacyl hydrolase 4.9
21-hydroxylase 4.8
pyroglutamyl peptidase II 4.7
CBPP 4.6
MGDG synthase 4.6
PdxH 4.6
bromelin 4.5
phosphofructokinase 1 4.4
phosphoinositide 5-phosphatase 4.4
oviductin 4.3
IgA protease 4.3
PWD 4.2
phospholipid hydroperoxide glutathione peroxidase 4.1
dihydrolipoamide succinyltransferase 4.1
galactosyltransferase I 4.1
IOR 4.0
EC 4.4.1.5 4.0
choline dehydrogenase 4.0
oxytocinase 4.0
estrogen sulfotransferase 3.9
prostaglandin F synthase 3.9
KAR 3.9
separase 3.8
polypeptide N-acetylgalactosaminyltransferase 3.7
phosphatidylinositol phospholipase C 3.7
carboxypeptidase E 3.6
2,4-dienoyl-CoA reductase 3.5
pregnancy-associated plasma protein-A 3.5
galactose-1-phosphate uridylyltransferase 3.5
thyroid peroxidase 3.5
site-1 protease 3.4
HSD 3.4
mannosidase II 3.2
methylenetetrahydrofolate reductase 3.2
methylenetetrahydrofolate reductase 3.2
IgA1 protease 3.2
SRR 3.2
ornithine aminotransferase 3.1
LIS 3.0
5alpha-reductase 3.0
5alpha-reductase 3.0
alpha-glucosidase 3.0
jararhagin 3.0
ubiquinol-cytochrome c oxidoreductase 2.9
VIP1 2.8
TGT 2.8
NAO 2.8
lysine acetyltransferase 2.8
3beta-hydroxysteroid dehydrogenase 2.7
estrogen sulfotransferase 2.7
PI-PLC 2.7
Lod 2.6
17beta-HSD 2.6
methionine synthase reductase 2.6
galactocerebrosidase 2.6
uridyltransferase 2.5
CGT 2.5
phosphatidylethanolamine N-methyltransferase 2.4
CO dehydrogenase 2.4
hyaluronidase 2.4
sphingomyelin synthase 2.4
phosphomannomutase 2.4
NCP 2.3
sulfhydryl oxidase 2.3
paraoxonase 2.3
GAR 2.3
spermidine/spermine N1-acetyltransferase 2.3
alpha-L-fucosidase 2.3
RNase III 2.3
alpha-L-fucosidase 2.2
prostaglandin synthetase 2.2
HtrA 2.2
proline oxidase 2.2
p80 2.2
more...
Compound
Clomiphene citrate 8.5
Epimestrol 7.9
Clomid 7.7
Ouabagenin 7.7
Clomiphene 7.7
1H-indazole-3-carboxylic acid 7.2
DABI 6.9
Protodioscin 6.9
Benzothiazoline 6.9
Testolactone 6.7
Nicotine tartrate 6.7
WIN 18,446 6.7
Indicine 6.7
DBCP 6.5
cholesta-3,5-diene 6.4
Letrozole 6.4
CFN 6.2
CoQ6 6.2
2,2-bis(bromomethyl)-1,3-propanediol 6.2
Cabergoline 6.1
Chloral 6.1
Fenarimol 6.1
Danazol 5.9
Medroxyprogesterone 5.9
Boldenone 5.9
Nafarelin 5.8
Gossypol 5.8
Gossypol 5.8
Lead oxide 5.7
DETP 5.6
PID 5.6
PID 5.6
Phenergan 5.5
Biguanide 5.4
T undecanoate 5.4
8-Isoprostane 5.4
4-tert-Octylphenol 5.4
S.T.D. 5.3
Mesterolone 5.3
4-tert-Octylphenol 5.3
5,10-Methylenetetrahydrofolate 5.3
Cyclamate 5.3
SCMC 5.2
Bromocriptine 5.2
Phosphinothricin 5.2
Phentermine 5.2
Nicarbazin 5.2
IBT 5.1
Chromomycin A3 5.1
Norethisterone acetate 5.0
methyl trifluoromethanesulfonate 5.0
Punicalagin 4.8
p-Bromophenacyl bromide 4.8
Microcephalin 4.8
Phenylenediamine 4.7
Swainsonine 4.6
Oxamniquine 4.6
Coumestrol 4.6
17-OHP 4.6
undecanal 4.6
undecanal 4.6
DDF 4.6
BEP 4.6
BNS 4.6
SHT 4.5
DPBS 4.5
Ornidazole 4.5
Procarbazine 4.5
Equol 4.4
Lynestrenol 4.4
dUDP 4.4
Desogestrel 4.3
Zwittergent 3-14 4.3
Cefonicid 4.3
DMDP 4.3
Mancozeb 4.3
Velban 4.3
Guggulsterone 4.3
5,10-methylene-THF 4.3
Anastrozole 4.2
more...