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Query: UMLS:C0021359 (infertility)
 26,075 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In any case of sterility the andrological examination is absolutely necessary; firstly because 50 per cent of the examined men don't show normospermic ejaculate and secondly because nearly 14 per cent of the examined men are infertil. Fertility of man is normal in hypospermia (20 to 40 mill. spermatozoa per ml); it is decreased in oligospermia (less than 20 mill per ml), but real possible. Even kryptospermia (less than one million spermatozoa per ml) can not be identified absolutely with infertility. Hypokinesis and increase of pathomorphic spermatozoa apparently prevent the opportunity of conceptions. It is doubtful that fructose of spermaplasma is a certain criterion of fertility. Extra-matrimonial conceptions probably often occur, for that reason any statement about fertility of man is inaccurately.
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PMID:[Interpretation and misinterpretation of sperm findings as fertility criterion]. 86 48

An appropriate examination is absolutely necessary in male infertility because of the frequency of andrological cause of marriage sterility. Half of the examined men do not show normospermic ejaculation and a 1/7 of the cases are infertile. Fertility of men in case of hypospermia is 20-40 million spermatozoa/ml and is comparable to normospermia (40 million spermatozoa/ml). It is decreased in oligospermia (less than 20 million/ml). Even cryptospermia (less than 1 million spermatozoa/ml) cannot be identified as infertility. Hypokinesis and increase of pathomorphic spermatozoa apparently prevent conception. It is doubtful that fructose of spermaplasma is a certain criterion of fertility. Extramatrimonial conceptions occur frequently, therefore any statement about fertility of man is inaccurate.
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PMID:[Correlation of spermatozoal parameters and male fertility]. 88 Oct 76

An assay for measuring the acrosomal proteinase activity of human spermatozoa with the use of a microscope slide coated with a thin layer of gelatin as a protein substrate was developed and applied to study the semen of 82 males from infertile couples and 15 normal donors. Acrosomal protease activity is indicated by a clear area of proteolyzed gelatin (halo) about the sperm head. Probit analysis revealed two populations divided at a halo diameter of 14 microns. The patient samples were grouped according to semen quality. The mean proteinase activity for most of the infertile groups was significantly below the control and more of the infertile men had a halo diameter less than 14 microns. Decreased activity was also found in 37% of patients with normal semen analysis. It is concluded that low acrosomal proteinase activity is associated with infertility. This reliable, inexpensive and rapid assay may prove to be helpful as an adjunct to semen analysis in the infertility work-up.
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PMID:Acrosomal proteinase activity of human spermatozoa and relation of results to semen quality. 306 43