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Query: UMLS:C0021359 (infertility)
 26,075 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Peritoneal fluid (PF) was obtained during the early follicular phase in 24 women at laparoscopy as part of infertility investigation. The cells present in PF were pelleted and cultured. Developing endometrial epithelial cell colonies were identified in 19 women (79%). Identification of these cell colonies was facilitated using the monoclonal antibody BW 495/36 as specific marker. The number of endometrial epithelial cell colonies showed a large variation (1 to 200 or more PF sample). No significant distinction in incidence and number of cell colonies was found between women with minimal (n = 11) and without endometriosis (n = 12). A significant correlation with number of cell colonies was found in women with infertility and no mechanical and male infertility factors. These data indicate that retrograde transport of viable endometrial cells during menstruation occurs in most women with patent tubes. Implications of the results for the relation between retrograde menstruation, endometriosis, and infertility are discussed.
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PMID:Endometrial epithelial cells in peritoneal fluid during the early follicular phase. 199 28

For couples with unexplained or male infertility, intraperitoneal (IP) insemination in induced cycles is a method that increases the chance of fertilization. Seventy-seven couples with male subfertility were subjected to 120 IP insemination cycles and 31 with unexplained sterility to 44 cycles. As a consequence of the treatment, 23 pregnancies were obtained, with pregnancy rates of 23% per cycle and 32% per patient for unexplained infertility and 11% and 17% for male subfertility. Pregnancy loss rate was quite elevated: 9 clinical abortions and 1 ectopic. Intraperitoneal insemination appears to be a relatively noninvasive way to deal with unexplained or male factor infertility, well worth trying before moving on to more invasive and costly approaches, such as gamete intrafallopian transfer or in vitro fertilization.
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PMID:Intraperitoneal insemination in the treatment of male and unexplained infertility. 199 31

Mobile epididymis plays an important role in the genesis of male infertility. It constituted 9 percent of a consecutive series of idiopathic infertility. Of 200 patients examined (100 fertile and 100 infertile), mobile epididymis was detected in 9 infertile patients. The clinical picture is characteristic. Epididymis is widely separated from testicle and moves freely from side to side. Its body and tail are ill formed and the epididymovasal angle is obtuse. Azoospermia was persistent in 3 patients and intermittent in 6 patients. Testicular biopsy showed tubular dilatation. Epididymopexy was performed in the 9 patients to fix the epididymis to testicle: 3 patients showed improvement in semen quality with two resultant pregnancies. Failures were due to advanced testicular damage. Infertility in mobile epididymis appears to result from obstruction of efferent ductules, testicular ischemia, and/or interference with sperm maturation, transport, or delivery.
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PMID:Mobile epididymis. A new clinicopathologic entity in genesis of male infertility and its treatment by epididymopexy. 199 85

Data on costs associated with episodes of disease and disease prevention, including expenditures for veterinary services, were collected from 57 California beef cow-calf herds during 1988-1989 as part of the National Animal Health Monitoring System. Mean cost associated with episodes of disease was $33.90/cow-year, with $0.78 and $1.37/cow-year being spent for veterinary services and drugs, respectively. The highest cost for veterinary services related to episodes of disease were for dystocia, lameness, and ocular carcinoma. For disease prevention, mean expenditures for veterinary services were $1.67/cow-year, nearly all of which was spent on prevention of reproductive tract conditions. Preventive expenditures for veterinary services related to female infertility (pregnancy examination), vaccination against brucellosis and male infertility (breeding soundness examination) were $0.72, $0.39, and $0.22/cow-year, respectively. Many costs associated with episodes of disease and disease prevention were similar to those reported from Colorado National Animal Health Monitoring System beef herds.
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PMID:Expenditures for veterinary services and other costs of disease and disease prevention in 57 California beef herds in the National Animal Health Monitoring System (1988-1989). 201 26

Tuberculosis of the genitourinary tract is a well-known cause of male infertility. However, infertility from infection by nontuberculous mycobacterium has not been reported. Herein, we present a case of seminal vesiculitis due to Mycobacterium gastri in a diabetic patient leading to male infertility. Improvement in semen quality was noticed after 6 months of therapy with isoniazid, ethambutol and rifampicin.
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PMID:Seminal vesiculitis due to Mycobacterium gastri leading to male infertility. 202 86

Male infertility is a poorly understood problem that often receives awkward management from health care providers. Some abnormalities of the male reproductive system that lead to infertility can be treated successfully, others cannot. Any diagnosis of infertility can create an emotional crisis for the infertile male and his partner, which requires support, understanding and counseling from clinicians. This article examines the process of evaluating reproductive function, determining patient needs, establishing a plan of care and understanding treatment options for the infertile male.
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PMID:Male infertility: a challenge for primary health care providers. 202 55

Results are presented of gamete intra-Fallopian transfer with cryopreserved donor semen in cases of male infertility with azoospermia or extreme oligozoospermia. The female partners had no detectable infertility problems and they had first received 10 cycles of intracervical AID without success. Forty-one GIFT cycles performed on 22 such patients gave an overall pregnancy rate of 26.8% (11/41). In 64% (9/14) of these cases, pregnancy occurred after the first GIFT attempt. From these results it is suggested that GIFT with donor semen may be a reasonable alternative after AID failure. The probable reasons for success of GIFT are discussed.
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PMID:Gamete intra-fallopian transfer with cryopreserved donor semen following AID failure. 208 5

An inquiry was carried out in 91 students of the V year of Medical Academy, potential semen donors for artificial insemination, for gaining an insight into the degree of acceptance of this problem in their present situation and in assumed possible infertility of them or their partners, and the foreseen results of sociocultural consequences of the infertility of one of the partners in a married couple, as regarded by the responders. The highest grade of acceptance of semen donation for heterologous insemination was shown by students living in cities and coming from the families of the intelligentsia. Among the factors determining this attitude the most frequent were: altruistic attitude, followed by economic gains. Religion had only a slight influence on this attitude. In the studied group a higher acceptance was gained in case of female infertility by resolving the problem by use of the so called proxy-mother, than by artificial insemination in case of male infertility. Nearly half the responders supported adoption of a child in preference to artificial insemination, while heterologous insemination was preferred mainly by responders coming from small towns and villages.
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PMID:[The problem of marital infertility caused by the male partner pathology in view of potential semen donors]. 208 81

The human reproductive process entails numerous possible sites for immunological intervention aimed at controlling fertility. Currently under investigation are a vaccine based on gonadotropin releasing hormone (GnRH) interception, regulation of male fertility by immunointerception of follicle-stimulating hormone (FSH), vaccines based on the neutralization of human chorionic gonadotropin (hCG), and anti-hCG immunization. In Phase I clinical trials, passive transfer of anti-GnRH antibody has produced short-term infertility; long-term infertility has been achieved through active immunization against the decapeptide. In terms of FSH, the research has failed to demonstrate how long-term neutralization brings about male infertility. Before immunization against FSh is considered further as a means of immunocontraception, further studies are needed on the required levels of physiological FSH and testosterone for normal testicular functions to be maintained. 4 other Phase I clinical trials in this area involve vaccines based on the beta subunit of hCG or its fragment. Preliminary results from these trials suggest that contraceptive antibody titers can be obtained with permissible adjuvants, especially tetanus toxoid.
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PMID:Relevance of immuno-contraceptive vaccines for population control. I. Hormonal immunocontraception. 212 20

We report five patients who consulted for orchialgia in whom the diagnosis of testicular microlithiasis was made by means of scrotal sonography. Four showed oligo or azzosperm and 4 had their testis diminished in size. The echographic findings were characteristic and consisted of multiple small echogenic nonshadowing images, scattered in both testis. Atrophy of the germinal epithelium and impairment of spermiogenesis associated to intratubular calcic microspheres were demonstrated in 3 cases. Testicular microlithiasis is not generally recognized as a cause for infertility and we proposed that scrotal sonography should be used in workup for male infertility.
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PMID:[Testicular microlithiasis: echographic diagnosis of a new cause for orchialgia and infertility]. 213 9


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