Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0021051 (immunodeficiency)
71,517 document(s) hit in 31,850,051 MEDLINE articles (0.03 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
CD4 8400
Sep 4908
CD8 2217
lymphoid 1954
Mol 1880
cytokine 1717
Gag 1618
gag 1564
interferon 1553
env 1414
CCR5 1404
envelope glycoprotein 1386
glycoprotein 1118
CXCR4 1097
p24 1096
IgA 908
integrase 902
pol 892
SIV 835
Env 827
chemokine 825
Gen 811
p24 antigen 723
X-linked 693
HLA 683
protease inhibitor 679
envelope protein 676
thymus 671
tat 615
tumor necrosis factor 615
APA 576
IFN 553
IL-2 536
interleukin-2 516
major histocompatibility complex 497
Pol 482
IFN-gamma 465
severe combined immunodeficiency 431
She 413
MT-4 412
THC 397
gut 390
IgE 389
fused 388
interferon-gamma 382
surface antigen 380
IL-6 367
non-Hodgkin's lymphoma 361
IL-10 354
polypeptide 342
tumor necrosis factor alpha 334
NMR 332
TNF 330
IL-4 330
RNase H 324
MHC 321
lipopolysaccharide 321
STD 304
chemokine receptor 299
RANTES 297
Gag protein 289
insulin 289
T cell receptor 287
transactivator 282
HLA-DR 276
DNA polymerase 274
CD4 molecule 267
APOBEC3G 263
San 256
TNF-alpha 254
p17 248
CD28 246
CD4 receptor 246
tRNA 244
NL4 229
CSF 220
ATP 219
endoplasmic reticulum 215
human leukocyte antigen 208
hemoglobin 207
more...
Disease
immunodeficiency 71517
HIV 25495
AIDS 14377
cancer 3589
tuberculosis 2682
hepatitis C 2563
hepatitis B 2333
infectious diseases 2307
leukemia 1980
virus infection 1911
cytomegalovirus 1790
tumor 1683
lymphoma 1474
Epstein 1450
viremia 1299
Infection 1261
Mycobacterium 1249
Kaposi's sarcoma 1212
herpes simplex 1154
pneumonia 1060
lymphadenopathy 945
STD 863
anemia 829
influenza 774
syphilis 751
SCID 724
hepatitis 711
Hodgkin's disease 697
vaccinia 644
opportunistic infection 637
diabetes 631
PCP 624
encephalitis 612
hypogammaglobulinemia 610
dementia 594
thrombocytopenia 579
ARC 536
immune deficiency 480
liver disease 478
herpes 474
sepsis 458
non-Hodgkin's lymphoma 441
malnutrition 433
CEM 431
cirrhosis 427
renal disease 426
Cryptococcus neoformans 424
Wiskott-Aldrich syndrome 423
lymphopenia 419
West 417
ATM 412
candidiasis 409
depression 408
stomatitis 398
neutropenia 395
chronic hepatitis 391
haemophilia 378
sepsis 371
chronic granulomatous disease 369
varicella 368
malaria 367
B-cell lymphoma 359
systemic lupus erythematosus 359
meningitis 356
fungal infection 341
X-linked agammaglobulinemia 341
pulmonary tuberculosis 324
toxoplasmosis 318
autoimmune disease 315
carcinoma 315
graft-versus-host disease 310
asthma 308
arthritis 293
rash 277
Common variable immunodeficiency 273
PML 262
cardiovascular disease 260
MAC 257
oral candidiasis 255
drug abuse 253
more...
Symptom
diarrhea 958
pain 401
splenomegaly 247
cough 244
headache 228
stigma 204
abdominal pain 192
fatigue 184
seizures 177
weakness 160
hepatosplenomegaly 155
vomiting 154
dyspnea 151
exhaustion 133
nausea 127
anorexia 105
ataxia 94
hepatomegaly 88
erythema 84
respiratory distress 83
Ill 82
cerebellar ataxia 77
anesthesia 76
cachexia 69
collapse 67
fever of unknown origin 54
discomfort 53
myalgia 52
lethargy 51
arthralgia 51
chills 48
discomfort 47
chest pain 46
night sweats 44
wheezing 35
pallor 35
sore throat 34
shortness of breath 34
starvation 33
hemoptysis 33
hypotonia 32
overweight 31
back pain 29
memory loss 28
adenitis 27
ENT 27
productive cough 25
paraparesis 23
tachypnea 23
dizziness 23
nausea and vomiting 23
tremor 22
asthenia 21
paresthesia 21
acute abdomen 20
insomnia 20
epigastric pain 20
apathy 20
thinning 19
paresis 18
dysarthria 18
photophobia 18
numbness 17
chronic cough 16
constipation 14
hemiplegia 14
syncope 14
dystonia 14
hypoproteinemia 14
bone pain 13
hopelessness 13
vertigo 13
neck stiffness 13
analgesia 13
urethral discharge 12
dysuria 12
myoclonus 12
agitation 12
exertional dyspnea 12
emaciation 12
more...
Drug
Dermatol 677
IL-2 540
AZT 509
AZT 509
IFN-gamma 458
CSF 274
lysine 218
PMPA 157
Asthma 148
Asn 112
TAT 100
Cardiovasc 94
PMEA 86
ddI 86
Gel 79
p75 76
Tenofovir 71
Kenyan 58
ROC 51
DNase I 50
Monit 49
Indinavir 49
Raltegravir 48
BLM 46
Rituximab 45
ENT 44
PFA 44
TAK 43
Enfuvirtide 42
MAP 40
Adenosine deaminase 39
BCG vaccine 38
ampicillin 38
Acyclovir 37
G-CSF 36
-deoxyadenosine 36
Biopolymers 35
vitamin E 34
ATV 34
Tenofovir disoproxil fumarate 33
Fluconazole 33
IFN-beta 33
ascorbate 33
Maraviroc 30
Alanine 30
Isoniazid 27
ABC 27
Aztec 27
Vitamin A 26
Dial 25
Nephron 24
Itraconazole 23
PCP 23
Tuberculin 22
Nephron 20
ROS 20
G418 20
Darunavir 20
HPMPC 20
Ethanol 19
Truvada 19
Norplant 18
Dakar 18
EE2 17
Trimethoprim-sulfamethoxazole 17
Ganciclovir 16
NVP 16
Bayer 16
Albumin 15
TPV 15
Spectrum 15
Truvada 14
Heme 14
Leaf 14
Growth hormone 14
CTX 13
Ketoconazole 13
Growth hormone 13
lactose 13
MDS 13
more...
Enzyme
reverse transcriptase 3830
focal adhesion kinase 587
RNA polymerase 504
HIV-1 protease 389
DNA polymerase 384
RNase H 354
transcriptase 274
protein kinase 268
mitogen-activated protein kinase 241
luciferase 232
chloramphenicol acetyltransferase 224
alanine aminotransferase 207
adenosine deaminase 192
adenosine deaminase 191
protein kinase C 186
ERK 185
proteasome 172
RNase 167
RNase 153
catalase 138
beta-galactosidase 135
alkaline phosphatase 127
thymidine kinase 122
NADPH oxidase 120
NADPH oxidase 119
peroxidase 106
TAT 100
P-glycoprotein 98
endonuclease 92
aspartate aminotransferase 87
caspase-3 85
trypsin 84
ATPase 78
cytidine deaminase 76
lactate dehydrogenase 75
glutathione S-transferase 75
aldehyde dehydrogenase 75
MDR 73
MIP 72
purine nucleoside phosphorylase 68
ACS 65
CD10 62
DNA methyltransferase 60
CYP3A4 60
superoxide dismutase 58
Rex 58
calcineurin 57
neuraminidase 54
IKK 50
phosphatidylinositol 3-kinase 49
ribonuclease 47
AOR 47
ribonuclease 47
BMT 47
deaminase 46
lysozyme 43
DNase 42
furin 41
granzyme B 41
APC 39
thrombin 38
pepsin 38
MEK 36
ribonucleotide reductase 35
ribonucleotide reductase 34
phospholipase C 33
deoxycytidine kinase 32
phosphoinositide 3-kinase 31
glutathione peroxidase 31
topoisomerase 30
creatine kinase 30
thromboplastin 29
caspase-8 29
firefly luciferase 29
NO synthase 28
cdc2 27
phosphoglycerate kinase 26
caspase-1 26
endoglycosidase H 25
alpha-glucosidase 25
more...
Compound
DNA 7532
Clin 7390
Dec 5179
AZT 700
water 566
calcium 534
tryptophan 528
arginine 488
tyrosine 486
oxygen 465
lysine 448
His 433
alanine 429
acetate 427
cysteine 385
leucine 375
sulfate 345
TNF 330
zinc 327
phosphate 324
sodium 322
glucose 290
hydrogen 277
TAR 268
serine 266
galactose 256
Asp 228
3TC 225
ATP 219
Phe 214
Ile 213
threonine 206
ethanol 190
proline 169
creatinine 166
tryptophan 165
d4T 164
iron 164
salt 162
methionine 162
tryptophan 160
tryptophan 160
neopterin 154
Primatol 153
Primatol 153
Primatol 153
COS 145
pyrimidine 145
pyrimidine 145
Gly 142
BCG 140
glutamate 134
PEG 133
nitric oxide 127
Abbott 126
Cardiol 122
THP 111
THP 110
TTP 109
TEM 109
SDS 108
nitrogen 106
urea 104
NH2 102
silver 96
isoleucine 85
bromide 85
CAT 84
CAT 84
isoleucine 84
CAT 84
Mg2+ 84
PMEA 84
PMA 84
PEG 82
valine 82
GSH 81
GSH 81
glutamine 78
PMA 76
more...