Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0021051 (
immunodeficiency
)
71,517
document(s) hit in 31,850,051 MEDLINE articles (0.03 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
CD4
8400
Sep
4908
CD8
2217
lymphoid
1954
Mol
1880
cytokine
1717
Gag
1618
gag
1564
interferon
1553
env
1414
CCR5
1404
envelope glycoprotein
1386
glycoprotein
1118
CXCR4
1097
p24
1096
IgA
908
integrase
902
pol
892
SIV
835
Env
827
chemokine
825
Gen
811
p24 antigen
723
X-linked
693
HLA
683
protease inhibitor
679
envelope protein
676
thymus
671
tat
615
tumor necrosis factor
615
APA
576
IFN
553
IL-2
536
interleukin-2
516
major histocompatibility complex
497
Pol
482
IFN-gamma
465
severe combined immunodeficiency
431
She
413
MT-4
412
THC
397
gut
390
IgE
389
fused
388
interferon-gamma
382
surface antigen
380
IL-6
367
non-Hodgkin's lymphoma
361
IL-10
354
polypeptide
342
tumor necrosis factor alpha
334
NMR
332
TNF
330
IL-4
330
RNase H
324
MHC
321
lipopolysaccharide
321
STD
304
chemokine receptor
299
RANTES
297
Gag protein
289
insulin
289
T cell receptor
287
transactivator
282
HLA-DR
276
DNA polymerase
274
CD4 molecule
267
APOBEC3G
263
San
256
TNF-alpha
254
p17
248
CD28
246
CD4 receptor
246
tRNA
244
NL4
229
CSF
220
ATP
219
endoplasmic reticulum
215
human leukocyte antigen
208
hemoglobin
207
more...
Disease
immunodeficiency
71517
HIV
25495
AIDS
14377
cancer
3589
tuberculosis
2682
hepatitis C
2563
hepatitis B
2333
infectious diseases
2307
leukemia
1980
virus infection
1911
cytomegalovirus
1790
tumor
1683
lymphoma
1474
Epstein
1450
viremia
1299
Infection
1261
Mycobacterium
1249
Kaposi's sarcoma
1212
herpes simplex
1154
pneumonia
1060
lymphadenopathy
945
STD
863
anemia
829
influenza
774
syphilis
751
SCID
724
hepatitis
711
Hodgkin's disease
697
vaccinia
644
opportunistic infection
637
diabetes
631
PCP
624
encephalitis
612
hypogammaglobulinemia
610
dementia
594
thrombocytopenia
579
ARC
536
immune deficiency
480
liver disease
478
herpes
474
sepsis
458
non-Hodgkin's lymphoma
441
malnutrition
433
CEM
431
cirrhosis
427
renal disease
426
Cryptococcus neoformans
424
Wiskott-Aldrich syndrome
423
lymphopenia
419
West
417
ATM
412
candidiasis
409
depression
408
stomatitis
398
neutropenia
395
chronic hepatitis
391
haemophilia
378
sepsis
371
chronic granulomatous disease
369
varicella
368
malaria
367
B-cell lymphoma
359
systemic lupus erythematosus
359
meningitis
356
fungal infection
341
X-linked agammaglobulinemia
341
pulmonary tuberculosis
324
toxoplasmosis
318
autoimmune disease
315
carcinoma
315
graft-versus-host disease
310
asthma
308
arthritis
293
rash
277
Common variable immunodeficiency
273
PML
262
cardiovascular disease
260
MAC
257
oral candidiasis
255
drug abuse
253
more...
Symptom
diarrhea
958
pain
401
splenomegaly
247
cough
244
headache
228
stigma
204
abdominal pain
192
fatigue
184
seizures
177
weakness
160
hepatosplenomegaly
155
vomiting
154
dyspnea
151
exhaustion
133
nausea
127
anorexia
105
ataxia
94
hepatomegaly
88
erythema
84
respiratory distress
83
Ill
82
cerebellar ataxia
77
anesthesia
76
cachexia
69
collapse
67
fever of unknown origin
54
discomfort
53
myalgia
52
lethargy
51
arthralgia
51
chills
48
discomfort
47
chest pain
46
night sweats
44
wheezing
35
pallor
35
sore throat
34
shortness of breath
34
starvation
33
hemoptysis
33
hypotonia
32
overweight
31
back pain
29
memory loss
28
adenitis
27
ENT
27
productive cough
25
paraparesis
23
tachypnea
23
dizziness
23
nausea and vomiting
23
tremor
22
asthenia
21
paresthesia
21
acute abdomen
20
insomnia
20
epigastric pain
20
apathy
20
thinning
19
paresis
18
dysarthria
18
photophobia
18
numbness
17
chronic cough
16
constipation
14
hemiplegia
14
syncope
14
dystonia
14
hypoproteinemia
14
bone pain
13
hopelessness
13
vertigo
13
neck stiffness
13
analgesia
13
urethral discharge
12
dysuria
12
myoclonus
12
agitation
12
exertional dyspnea
12
emaciation
12
more...
Drug
Dermatol
677
IL-2
540
AZT
509
AZT
509
IFN-gamma
458
CSF
274
lysine
218
PMPA
157
Asthma
148
Asn
112
TAT
100
Cardiovasc
94
PMEA
86
ddI
86
Gel
79
p75
76
Tenofovir
71
Kenyan
58
ROC
51
DNase I
50
Monit
49
Indinavir
49
Raltegravir
48
BLM
46
Rituximab
45
ENT
44
PFA
44
TAK
43
Enfuvirtide
42
MAP
40
Adenosine deaminase
39
BCG vaccine
38
ampicillin
38
Acyclovir
37
G-CSF
36
-deoxyadenosine
36
Biopolymers
35
vitamin E
34
ATV
34
Tenofovir disoproxil fumarate
33
Fluconazole
33
IFN-beta
33
ascorbate
33
Maraviroc
30
Alanine
30
Isoniazid
27
ABC
27
Aztec
27
Vitamin A
26
Dial
25
Nephron
24
Itraconazole
23
PCP
23
Tuberculin
22
Nephron
20
ROS
20
G418
20
Darunavir
20
HPMPC
20
Ethanol
19
Truvada
19
Norplant
18
Dakar
18
EE2
17
Trimethoprim-sulfamethoxazole
17
Ganciclovir
16
NVP
16
Bayer
16
Albumin
15
TPV
15
Spectrum
15
Truvada
14
Heme
14
Leaf
14
Growth hormone
14
CTX
13
Ketoconazole
13
Growth hormone
13
lactose
13
MDS
13
more...
Enzyme
reverse transcriptase
3830
focal adhesion kinase
587
RNA polymerase
504
HIV-1 protease
389
DNA polymerase
384
RNase H
354
transcriptase
274
protein kinase
268
mitogen-activated protein kinase
241
luciferase
232
chloramphenicol acetyltransferase
224
alanine aminotransferase
207
adenosine deaminase
192
adenosine deaminase
191
protein kinase C
186
ERK
185
proteasome
172
RNase
167
RNase
153
catalase
138
beta-galactosidase
135
alkaline phosphatase
127
thymidine kinase
122
NADPH oxidase
120
NADPH oxidase
119
peroxidase
106
TAT
100
P-glycoprotein
98
endonuclease
92
aspartate aminotransferase
87
caspase-3
85
trypsin
84
ATPase
78
cytidine deaminase
76
lactate dehydrogenase
75
glutathione S-transferase
75
aldehyde dehydrogenase
75
MDR
73
MIP
72
purine nucleoside phosphorylase
68
ACS
65
CD10
62
DNA methyltransferase
60
CYP3A4
60
superoxide dismutase
58
Rex
58
calcineurin
57
neuraminidase
54
IKK
50
phosphatidylinositol 3-kinase
49
ribonuclease
47
AOR
47
ribonuclease
47
BMT
47
deaminase
46
lysozyme
43
DNase
42
furin
41
granzyme B
41
APC
39
thrombin
38
pepsin
38
MEK
36
ribonucleotide reductase
35
ribonucleotide reductase
34
phospholipase C
33
deoxycytidine kinase
32
phosphoinositide 3-kinase
31
glutathione peroxidase
31
topoisomerase
30
creatine kinase
30
thromboplastin
29
caspase-8
29
firefly luciferase
29
NO synthase
28
cdc2
27
phosphoglycerate kinase
26
caspase-1
26
endoglycosidase H
25
alpha-glucosidase
25
more...
Compound
DNA
7532
Clin
7390
Dec
5179
AZT
700
water
566
calcium
534
tryptophan
528
arginine
488
tyrosine
486
oxygen
465
lysine
448
His
433
alanine
429
acetate
427
cysteine
385
leucine
375
sulfate
345
TNF
330
zinc
327
phosphate
324
sodium
322
glucose
290
hydrogen
277
TAR
268
serine
266
galactose
256
Asp
228
3TC
225
ATP
219
Phe
214
Ile
213
threonine
206
ethanol
190
proline
169
creatinine
166
tryptophan
165
d4T
164
iron
164
salt
162
methionine
162
tryptophan
160
tryptophan
160
neopterin
154
Primatol
153
Primatol
153
Primatol
153
COS
145
pyrimidine
145
pyrimidine
145
Gly
142
BCG
140
glutamate
134
PEG
133
nitric oxide
127
Abbott
126
Cardiol
122
THP
111
THP
110
TTP
109
TEM
109
SDS
108
nitrogen
106
urea
104
NH2
102
silver
96
isoleucine
85
bromide
85
CAT
84
CAT
84
isoleucine
84
CAT
84
Mg2+
84
PMEA
84
PMA
84
PEG
82
valine
82
GSH
81
GSH
81
glutamine
78
PMA
76
more...