Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0021051 (immunodeficiency)
 71,517 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Strongyloides stercoralis hyperinfection is a rare but know complication in patients with intestinal parasitism. Immunosuppressive therapy and acquires immunodeficiency syndrome (AIDS) are major risk factors for dissemination. Diagnosis requires identification of larvae in body fluids or biopsy and the mortality rates can be as high as 80%. The enteric bacteria are carried by invasive larvae and this can result in septicemia, pneumonia, meningitis, and disseminated bacterial infection in many parts of the body. We present a case of Strongyloides stercoralis hyperinfection complicated by Escherichia coli bacteraemia in a 45-year-old man African with AIDS.
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PMID:[Strongyloides stercoralis hyperinfection in a patient with acquired immunodeficiency syndrome]. 1583 25

Hemophagocytic lymphohistiocytosis (HLH) in immunocompromised hosts is a fulminant syndrome of immune activation with high rates of mortality that may be triggered by infections or immunodeficiency. Rapid diagnosis and treatment of the underlying disorder is necessary to prevent progression to multiorgan failure and death. We report a case of HLH in a patient with human immunodeficiency virus, disseminated histoplasmosis, Mycobacterium avium complex, and Escherichia coli bacteremia. We discuss management of acutely ill patients with HLH and treatment of the underlying infection versus initiation of HLH-specific chemotherapy.
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PMID:Hemophagocytic Lymphohistiocytosis Secondary to Human Immunodeficiency Virus-Associated Histoplasmosis. 2656 35

Progressive multifocal leukoencephalopathy (PML) is caused by John Cunningham (JC) virus in immunocompromized patients such as those with human immunodeficiency virus (HIV) infection, hematological malignancy, autoimmune disorder, and immunodeficiency disorder as well as those undergoing chemotherapy or immunosuppressive therapy. No effective treatments have been established for PML, which commonly causes severe neurological sequelae. We describe the first case of PML in a patient without HIV infection who exhibited remarkable improvement following acute pyelonephritis with Escherichia coli bacteremia.
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PMID:Remarkable improvement in progressive multifocal leukoencephalopathy following acute pyelonephritis with bacteremia. 3061 16