Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0021051 (immunodeficiency)
 71,517 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

This study sought to evaluate the rate of detecting asymptomatic bacteriuria and endocervical infections in the black prenatal patients attending King Edward VIII Hospital (KEH), Durban, with the view of justifying a screening program. Screening for syphilis and human immunodeficiency virus (HIV) infection were also evaluated. 181 Asymptomatic black prenatal patients volunteered for the study and gave their written consent during their 1st antenatal visit. Each examination included the obtaining of endocervical swabs to detect endocervical infections (C trachomatis. N gonorrheae), serum for syphilitic and HIV testing, and a midstream specimen of urine for microscopy and culture. Asymptomatic bacteriuria was found in 5.6% of the patients in this study. Cervical infections were diagnosed microbiologically in 8.2% of the women: 4.1% with N gonorrheae and 4.7% with C trachomatis. Serological tests for sexually transmitted diseases showed the presence of syphilis in 7.6% and antibody to HIV in 1.9%. Overall, 1 or more sexually transmitted diseases were found in 16.5% of the women studied. This study suggests that all women who present for routine antenatal care in a setting such as Durban should be screened for lower genital tract infections. Ideally, this should include a midstream urine specimen for culture, serum for syphilitic and HIV antibody testing, and endocervical swabs for sexually transmitted pathogens. In developing countries, however, more reliable and cheaper methods of endocervical screening are necessary before antenatal screening for cervicovaginal infections can be justified.
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PMID:Urogenital tract infections in pregnancy at King Edward VIII Hospital, Durban, South Africa. 154 10

Urinary tract infections occur more frequently in diabetic patients than in the general population, with a relative risk ranging from 1.5 to 4, depending on the type of infection. The reasons underlying this higher susceptibility have not been established with certainty; urine glucose excression (which could facilitate bacterial urinary proliferation), immunodeficiency, a modified urothelium (resulting in a higher bacterial adhesion), and chronic neurologic bladder dysfunction have been advocated. Clinical presentation, bacterial epidemiology, and treatment of urinary tract infections in diabetic patients are similar to that of the general population. Accordingly, diabetes mellitus has recently been withdrawn from the list of criteria which define an urinary tract infection as complicated. Asymptomatic bacteriuria is particularly frequent in diabetic patients and should be checked routinely as it constitutes an important risk for subsequent symptomatic infection.
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PMID:[Urinary tract infections in diabetic patients]. 2536 87