Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0020672 (hypothermia)
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Human Gene/Protein
RNASE4 protein 10.8
creatine kinase, mitochondrial 9.8
RNA-binding motif 3 9.8
RNA-binding motif protein 3 9.8
PHCA 9.3
heat shock 70kDa protein 4 9.3
RBM3 9.0
ZNF333 8.8
RNA binding motif protein 3 8.5
cold-inducible RNA-binding protein 8.5
bombesin-like peptide receptor 8.3
MMSDH 8.3
SIP3 8.3
14-3-3 beta protein 8.0
Hb-2 8.0
CIRP 8.0
CIRBP 8.0
potassium channel 2 7.7
PDHK2 7.7
cysteine/histidine-rich 1 7.7
N143 7.5
100kD 7.4
FBL3 7.3
HTK 7.1
adenylyl cyclase type VI 6.9
HL-20 6.9
ribonuclease 4 6.9
uncoupling protein 4 6.8
twinfilin 1 6.8
monocarboxylic acid transporter 1 6.8
RBM1 6.8
HOT 6.7
SLC25A25 6.7
voltage-dependent anion channel 3 6.7
C1QC 6.7
GABABR1 6.6
IRG2 6.5
Nicotinamide mononucleotide adenylyltransferase 1 6.5
Freud-1 6.5
CPB 6.4
putative protein tyrosine phosphatase 6.4
NACA 6.4
SIP2 6.4
SCN4B 6.3
euchromatic histone-lysine N-methyltransferase 1 6.3
LCAD 6.3
CT9 6.1
NADH1 6.1
TAAR1 6.1
PFKFB2 6.0
ribosomal protein S3a 6.0
P83 6.0
eIF3i 6.0
ELOVL3 6.0
Voltage-gated potassium channel 5.9
Tonicity-responsive enhancer binding protein 5.9
5-HT1A 5.9
P145 5.9
ATIP 5.9
THH 5.8
ATAD3A 5.8
MIST1 5.8
hnRNP G 5.8
Dopamine D3 receptor 5.8
V4-6 5.8
CACT 5.7
Aquaporin-9 5.7
RIP-3 5.7
GPR32 5.7
kinase-like protein 5.7
hypoxanthine phosphoribosyltransferase 1 5.7
FOS protein 5.7
guanosine monophosphate reductase 5.7
IGSF1 5.7
14-3-3 beta 5.6
YWHAB 5.6
CHRNA2 5.6
ASB2 5.6
DSP-4 5.6
period1 5.5
more...
Disease
Semilobar holoprosencephaly 10.8
Aorticopulmonary paraganglioma 10.8
vagabond's disease 10.8
cold injury syndrome 10.8
Pituitary coma 10.8
inborn urea cycle disorder 9.8
Dilutional anaemia 9.8
Sopor 9.8
Algid malaria 9.8
ASD I 9.8
Circulatory arrest 9.7
Hypoxic-ischemic encephalopathy (HIE) 9.7
Neonatal encephalopathy 9.5
Myxedema coma 9.4
DIC in newborn 9.3
Acute coagulopathy 9.0
Citrate toxicity 8.8
Psychotic behavior 8.5
Staphylococcus aureus mediastinitis 8.5
Hypoxic-ischemic brain injury 8.2
Subendocardial ischemia 8.1
Hypophagia 8.1
Cold panniculitis 8.0
erythrocyanosis 8.0
Radiocontrast nephropathy 8.0
Vegetative endocarditis 8.0
Perinatal brain damage 7.9
Proximal myopathy 7.8
Primary congenital hypothyroidism 7.8
pregnancy infection 7.8
Congenital diaphragmatic eventration 7.7
swelling of the pituitary gland 7.5
Acute hyperkalemia 7.5
stage IV Hodgkin's disease 7.5
neonatal asphyxia 7.4
Uremic encephalopathy 7.4
Relative polycythaemia 7.4
catalepsy 7.3
Woakes' syndrome 7.3
Pili torti 7.1
Spinal cord ischemia 7.1
alcoholic ketoacidosis 7.1
Ventricular aneurysm 7.0
Klebsiella meningitis 7.0
Burn shock 7.0
Brain Ischemia 7.0
Cold urticaria 7.0
Miliaria crystallina 7.0
Diencephalic syndrome 6.9
LIH 6.9
Nodular goiter 6.9
NOMID 6.8
postperfusion syndrome 6.8
Diogenes syndrome 6.8
cross-dependence 6.8
Milk allergy 6.8
Monomorphic ventricular tachycardia 6.6
Cold agglutinin disease 6.5
acetonemia 6.5
Variola major 6.5
myxedema 6.5
Cardiorespiratory failure 6.5
Stereotypic behavior 6.5
Junctional ectopic tachycardia 6.5
acute alcoholism 6.3
Convulsive status epilepticus 6.3
coagulopathy 6.3
Acute monocytic leukemia 6.3
Haemophilus influenzae pneumonia 6.1
pentalogy of Fallot 6.1
Chronic hyponatremia 6.1
Left atrial myxoma 6.0
Anorexia nervosa and bulimia 6.0
Tumor morphology 6.0
Neonatal stroke 6.0
PCP intoxication 6.0
THC 6.0
Urethral obstruction 5.9
Reexpansion pulmonary edema 5.9
Respiratory morbidity 5.9
more...
Symptom
hypothermia 10.8
Induced hypothermia 10.5
Polypnea 8.8
Diaphragmatic flutter 8.8
Paroxysmal hypertension 7.1
Convulsive seizure 6.9
Fetal bradycardia 6.8
sinus headache 6.8
Very Low Birth Weight 6.8
Amputated 6.7
bradypnea 6.7
Mental status changes 6.6
muscular incoordination 6.3
aphagia 6.2
adipsia 6.1
abdominal rigidity 5.8
Pain and tenderness 5.8
hyperosmia 5.7
despair 5.6
POA 5.6
prostration 5.5
Todd's paralysis 5.5
labored breathing 5.4
tachypnea 5.4
Beau's lines 5.1
cardiovascular impairment 5.1
incoordination 5.1
Severe diarrhea 5.0
hypocapnia 5.0
neurological disability 5.0
Gasping 4.9
lethargy 4.9
GI irritation 4.9
Grimace 4.8
hypercapnia 4.8
Cold intolerance 4.7
staggering gait 4.7
diastolic murmurs 4.7
consciousness disturbance 4.6
oliguria 4.5
physical exhaustion 4.5
excessive sweating 4.5
Sedation 4.5
hyperesthesia 4.4
clonus 4.3
analgesia 4.3
cyanosis 4.2
anesthesia 4.1
emaciation 4.1
functional recovery 4.0
bewilderment 4.0
generalized erythema 4.0
paraparesis 3.9
hypoproteinemia 3.9
hypotonia 3.9
pallor 3.8
tremor 3.8
retching 3.7
lassitude 3.7
orthopnea 3.6
hyperoxia 3.5
ataxia 3.5
lightheadedness 3.4
hypalgesia 3.4
Spastic 3.4
anorexia 3.4
hangover 3.3
Regurgitation 3.3
Neurologic symptoms 3.3
ketonuria 3.3
skin irritant 3.3
respiratory distress 3.3
impaired motor coordination 3.3
flushing 3.2
chills 3.2
seizures 3.2
asterixis 3.1
rales 3.1
muscle rigidity 3.1
catatonia 3.1
more...
Drug
Processed aconite root 10.8
Lortalamine 9.8
Butaclamol hydrochloride 9.8
Hirtonin 9.8
Taltirelin hydrate 8.8
Dexamisole 8.8
Wytensin 8.3
Valerianae radix 8.0
Lifarizine 8.0
Pituitrin 7.8
Timiperone 7.7
Olvanil 7.7
Afloqualone 7.7
Geodon 7.7
Wytensin 7.7
Dopram 7.5
Oxypertine 7.5
Flesinoxan 7.5
Kallidinogenase 7.4
Piclamilast 7.4
Piclamilast 7.4
Geodon 7.4
Benzonatate 7.1
Alaproclate 7.0
Levophed 6.9
Brevibloc 6.8
Lubeluzole 6.8
Medetomidine 6.6
Amfonelic acid 6.5
Ziprasidone hydrochloride 6.5
SUN 1165 6.5
Pirenperone 6.4
Pentolinium 6.4
Oxyphenbutazone 6.3
Haloperidol decanoate 6.3
Sivelestat sodium hydrate 6.3
Oxyphenbutazone 6.2
Atracurium besylate 6.2
Doxapram 6.2
Alacepril 6.1
Rompun 6.1
Ergometrine 6.0
Bromfenac 6.0
Atipamezole 6.0
1,4-Butanediol 6.0
Zuclopenthixol 5.9
9-THC 5.9
Flurothyl 5.9
CPR 5.9
Alvimopan 5.7
LCBF 5.6
Catapres 5.6
Apomorphine 5.6
Stelazine 5.5
Zotepine 5.5
Lidoflazine 5.5
Cilomilast 5.5
Rolipram 5.4
Terguride 5.3
Calcium gluconate 5.3
Penfluridol 5.2
Quinine, 5.2
Sulfadimethoxine 5.2
Thiopentone 5.1
Almotriptan 5.1
Perphenazine 5.1
Pizotifen 5.1
Aricept 5.1
Flosequinan 5.1
Benserazide 5.1
Trimipramine 5.1
Nisoxetine 5.1
Reserpine 5.1
Pentothal 5.0
Butorphanol 5.0
Tenecteplase 5.0
Dipyrone 5.0
Magnesium chloride 4.9
Adenosine triphosphate 4.9
Proglumide 4.9
more...
Enzyme
nicotine oxidase 5.7
trehalose phosphorylase 5.3
HPI 5.2
GMP reductase 5.1
N-acetylglucosaminyltransferase II 4.9
nardilysin 4.9
palmitoyl-protein thioesterase 4.8
butyryl-CoA dehydrogenase 4.4
gastricsin 4.3
isovaleryl-CoA dehydrogenase 4.3
CPR 4.2
BAT 4.1
FAST 4.1
LMT 4.0
monoacylglycerol lipase 4.0
CNPase 3.8
deoxyguanosine kinase 3.7
malonyl-CoA decarboxylase 3.6
SCP 3.6
LIS 3.6
fatty-acid synthase 3.6
adenosine kinase 3.6
GABA transaminase 3.5
DMT 3.5
creatine kinase 3.4
PNL 3.4
clotting enzyme 3.4
SPT 3.4
homogentisate 1,2-dioxygenase 3.3
phosphatidylinositol-4,5-bisphosphate 3-kinase 3.2
monoamine oxidase 3.2
DOPA decarboxylase 3.1
AAE 3.1
phosphatidylethanolamine N-methyltransferase 3.0
lactic acid dehydrogenase 3.0
lactic acid dehydrogenase 2.9
tissue plasminogen activator 2.9
CPL 2.8
thromboxane synthase 2.7
tryptophan hydroxylase 2.6
SPT 2.6
uridine phosphorylase 2.6
cholinesterase 2.6
proline dehydrogenase 2.6
PCP 2.6
heparinase 2.5
BIS 2.5
thromboplastin 2.5
acetylcholinesterase 2.5
SCS 2.4
PDH 2.4
Omi/HtrA2 2.4
caspase-11 2.4
caspase-11 2.4
acyl-CoA dehydrogenase 2.4
prostaglandin synthetase 2.3
nicotinamide phosphoribosyltransferase 2.3
MPP 2.3
beta-hydroxybutyrate dehydrogenase 2.3
SNO 2.3
lactic acid dehydrogenase 2.3
NO synthase 2.2
lactate dehydrogenase 2.2
MAP 2.2
xanthine dehydrogenase 2.2
Protein 2 2.1
AST 2.1
arginine kinase 2.1
acetyl-CoA synthetase 2.0
aspartate aminotransferase 2.0
choline acetyltransferase 2.0
AMP-activated kinase 2.0
glutaminase 1.9
glucosylceramide synthase 1.9
MIP 1.9
caspase-3 1.9
cystathionine gamma-lyase 1.8
arginase 1.8
glutamate dehydrogenase 1.7
ADH 1.7
more...
Compound
2-ethyl-8-methyl-2,8-diazaspiro[4.5]decane-1,3-dione 10.8
Prednisolone sodium succinate 9.5
8-azaspiro[4.5]decane 8.8
1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one 8.5
2-hydroxy-3-methoxybenzoic acid 8.5
5-Iodotubercidin 8.3
5-Iodotubercidin 8.3
Iprindole 8.3
5-Iodotubercidin 8.3
N-(4-isopropylphenyl)acetamide 8.3
5-Iodotubercidin 8.1
Ketaset 8.0
Mepenzolate 8.0
U 14 8.0
beta-Amyrin 8.0
Sulfolane 8.0
Di-o-tolylguanidine 7.8
MIF-I 7.8
UH-301 7.7
alpha-Methyltryptophan 7.7
Tetrahydrozoline 7.7
Iminodibenzyl 7.7
5,5,5-trifluoroleucine 7.7
Calcium pantothenate 7.5
9-anthrol 7.5
Dopram 7.5
yohimban 7.4
2-(4-morpholinyl)ethyl 7.3
DHCA 7.3
Emopamil 7.3
MeODMT 7.2
2-(4-morpholinyl)ethyl 7.2
p-Synephrine 6.9
1,2,4,5-tetramethoxybenzene 6.9
alpha-Methylnoradrenaline 6.8
Mercaptoacetate 6.8
Neotetrazolium 6.8
[6]-Shogaol 6.8
AHCT 6.8
K486 6.8
Indeloxazine 6.8
3-O-Methyldopa 6.7
Metocurine 6.7
3-Acetylpyridine 6.7
CPB 6.5
3-methylisoquinoline 6.5
Histidyl-proline diketopiperazine 6.5
Pilocarpine hydrochloride 6.5
Amitraz 6.5
D-Methionine 6.5
Rubratoxin B 6.5
Iproniazid 6.5
Hydroxyamphetamine 6.5
1,2,3,5-tetrachlorobenzene 6.5
SR 141716 6.4
Nickel chloride 6.4
Dalmane 6.4
2-(1-pyrrolidinyl)ethyl 6.4
Neurotensin 6.3
PAPP 6.3
5-HTP 6.3
cyclopropanecarboxamide 6.3
5-HTP 6.3
Thiopental 6.2
AEK 6.2
Poly ICLC 6.2
p-Chloroamphetamine 6.2
2-phenyl-1H-indole 6.1
PAPP 6.1
Mescaline 6.1
Clorazepate 6.1
Phorone 6.1
Tetrahydrocannabinol 6.0
Phorone 6.0
Biperiden 6.0
Pimozide 6.0
DNBA 5.9
cyclohexanecarboxamide 5.9
Atracurium 5.9
Oxotremorine 5.9
more...