Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0020672 (
hypothermia
)
17,327
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Sep
1182
ATP
224
Mol
221
insulin
211
CA1
210
lipopolysaccharide
210
cytokine
196
5-HT1A
180
5-hydroxytryptamine
169
hemoglobin
152
tumor necrosis factor
143
She
135
IL-6
130
CO2
127
Pol
121
GABA
107
MRI
104
caspase-3
99
TNF
98
LPS
95
neurotensin
95
albumin
87
THC
78
beta-endorphin
77
CB1
77
nitric oxide synthase
76
creatine kinase
74
IL-10
72
cannabinoid receptor
72
Gen
69
fibrinogen
68
lactate dehydrogenase
63
axonal
61
vasopressin
61
calcium channel
58
NMDA receptor
58
ADP
58
TNF-alpha
57
cage
56
interleukin-6
56
CSF
55
acetylcholinesterase
55
superoxide dismutase
55
thyroid hormone
54
opioid receptor
54
erythropoietin
53
CPR
53
CA3
52
AMP
52
ATPase
49
thrombin
49
inducible nitric oxide synthase
47
prothrombin
46
Bcl-2
45
DBA
45
bombesin
44
glial fibrillary acidic protein
44
ACTH
44
olfactory
43
muscarinic receptor
43
penumbra
42
SCH
42
CPB
42
GSH
41
gut
41
leptin
38
NMR
38
tissue plasminogen activator
38
5-HT receptor
37
aspartate aminotransferase
36
collagen
36
cyclooxygenase
36
thromboplastin
36
thyrotropin-releasing hormone
35
prolactin
35
growth hormone
35
Q10
35
5-HT2A
35
CB2
35
glucagon
34
ICP
34
interferon
33
TRH
32
Mal
31
catalase
31
neuron-specific enolase
30
mast cell
30
Rec
29
endoplasmic reticulum
29
ASA
29
uncoupling protein 1
29
5-HT1B
29
alanine aminotransferase
28
neuropeptide Y
28
cholecystokinin
28
oxytocin
28
TRPV1
28
ANOVA
28
adenosine receptor
27
HSP70
27
phosphodiesterase
27
adenylate cyclase
27
LDH
27
microsomal
26
nicotinic acetylcholine receptor
26
Mil
26
rat)
26
IgE
26
arginine vasopressin
25
GCS
25
IL-8
24
myeloperoxidase
24
serum albumin
24
NTR
24
p53
23
dopamine D2 receptor
23
uncoupling protein
23
CBF
23
ubiquitin
23
cytochrome c
23
5-HT2 receptor
23
WIN
23
c-fos
23
glutamate receptor
23
TLR4
22
mouse)
22
IL-1
22
heat shock protein
22
cold-inducible RNA-binding protein
21
Pseudomonas
20
MRS
20
tumor necrosis factor alpha
20
fur
20
ERK
20
C-reactive protein
20
CAS
20
PLA
20
lamp
19
somatostatin
19
adrenocorticotropic hormone
19
Cytokine
19
CPK
19
tyrosine hydroxylase
19
myoglobin
19
p38
19
renin
19
tau protein
18
chemokine
18
IFN-gamma
18
JNK
18
cyclooxygenase-2
18
glutathione peroxidase
18
brain-derived neurotrophic factor
18
NAD
18
cytochrome
18
MAP
18
COX-2
17
substance P
17
polypeptide
17
fatty acid amide hydrolase
17
more...
Disease
cold
1867
ischemia
1565
stroke
740
encephalopathy
594
coma
516
depression
486
cerebral ischemia
381
coagulopathy
331
sepsis
314
ventricular fibrillation
303
hypertension
301
hypoglycemia
293
sepsis
288
myocardial infarction
218
catalepsy
211
tumor
191
fits
150
cancer
147
heart failure
146
hyperglycemia
141
dehydration
136
brain edema
132
pneumonia
131
myocardial ischemia
128
prolapse
119
diabetes
119
anemia
110
heart disease
105
pulmonary hypertension
102
obesity
101
hypothyroidism
99
renal failure
95
aortic aneurysm
92
ventricular septal defect
91
Evans
89
paraplegia
85
pulmonary edema
85
cerebral palsy
84
thrombocytopenia
84
epilepsy
82
respiratory failure
79
Alzheimer's disease
79
THC
77
status epilepticus
77
SEM
77
subarachnoid hemorrhage
72
acute myocardial infarction
71
pulmonary embolism
64
congestive heart failure
64
coronary artery disease
64
malnutrition
61
disseminated intravascular coagulation
61
renal cell carcinoma
54
aortic regurgitation
52
aggression
50
cerebral infarction
50
acute renal failure
47
neonatal asphyxia
46
anaphylaxis
46
lactic acidosis
46
cognitive impairment
45
DBA
45
NAME
45
Best
45
influenza
45
atrial septal defect
45
prematurity
45
infectious diseases
42
SCH
42
alcoholism
41
hyperphagia
41
GSH
41
schizophrenia
40
myxedema
40
aortic stenosis
39
Hypoxic-ischemic encephalopathy (HIE)
37
confusion
35
adult respiratory distress syndrome
35
raised intracranial pressure
35
necrotizing enterocolitis
34
hepatic encephalopathy
34
ICP
34
Circulatory arrest
33
Brown
33
diabetic ketoacidosis
33
pancreatitis
33
atherosclerosis
32
peritonitis
31
delirium
31
mitral regurgitation
31
hypercalcemia
31
alkalosis
31
malaria
30
respiratory acidosis
30
Infection
29
bacteremia
29
suicide
28
encephalitis
28
sickle cell disease
27
West
27
Marfan syndrome
27
acute pancreatitis
27
compartment syndrome
27
cardiomyopathy
27
meningitis
27
leukopenia
27
abdominal aortic aneurysm
27
physical dependence
25
Myxedema coma
25
Parkinson's disease
25
cardiac tamponade
25
renal insufficiency
25
asthma
24
immaturity
24
chronic obstructive pulmonary disease
24
ventricular hypertrophy
23
dementia
23
hyperthyroidism
23
hepatitis
23
metastases
23
psychosis
22
virus infection
22
Wernicke's encephalopathy
22
vascular disease
22
amnesia
22
neuroblastoma
22
brain dysfunction
22
aggressiveness
22
right heart failure
21
type 2 diabetes
21
malignant hyperthermia
21
chronic renal failure
21
deep vein thrombosis
20
hydrocephalus
20
memory impairment
20
neuropathy
20
dissecting aneurysm
20
MRS
20
cirrhosis
20
anorexia nervosa
20
hypernatremia
20
multiple sclerosis
20
atrioventricular block
20
liver disease
19
hemiparesis
19
Cannabis
19
hyperbilirubinemia
19
cerebral aneurysm
19
stereotypies
19
diabetes insipidus
19
blindness
18
leukemia
18
Neonatal encephalopathy
18
akinesia
18
sudden infant death syndrome
18
uterus
18
carcinoma
18
Esophageal
18
fluid overload
17
pertussis
17
more...
Symptom
hypothermia
17327
anesthesia
1047
seizures
396
analgesia
296
pain
290
tremor
137
vomiting
124
functional recovery
118
hypercapnia
117
diarrhea
109
collapse
107
respiratory distress
103
ataxia
100
lethargy
93
anorexia
77
starvation
67
weakness
64
tachypnea
60
dyspnea
59
fatigue
56
hypotonia
46
despair
43
discomfort
43
discomfort
43
Induced hypothermia
41
exhaustion
41
sleepiness
38
nausea
38
cyanosis
37
headache
36
agitation
34
flushing
33
hyperoxia
33
angina
32
incoordination
32
hypocapnia
30
syncope
27
nausea and vomiting
25
spasm
24
oliguria
23
paraparesis
23
chills
22
abdominal pain
22
chest pain
21
regurgitation
21
cough
20
paresis
20
pallor
19
myoclonus
17
neurological disability
16
Sedation
16
dizziness
14
POA
14
constipation
13
back pain
13
hemiplegia
12
cachexia
12
erythema
11
shortness of breath
11
bradypnea
11
acute stress
11
consciousness disturbance
11
Ill
10
exertional dyspnea
10
emaciation
10
spasticity
10
memory loss
10
splenomegaly
10
hepatomegaly
9
hypoproteinemia
9
paresthesia
9
prostration
9
apathy
9
hunger
8
polyuria
8
clonus
8
aphagia
8
hemoptysis
7
dystonia
7
overweight
7
numbness
7
adipsia
7
twitching
7
excessive sweating
7
acute pain
7
polydipsia
6
chorea
6
hyperesthesia
6
hypertonia
5
muscle rigidity
5
acidity
5
thinning
5
bradykinesia
5
insomnia
5
labored breathing
5
rhinorrhea
5
catatonia
5
hoarseness
4
abnormal gait
4
asthenia
4
dysarthria
4
retching
4
hypersomnia
4
nasal discharge
3
partial seizure
3
cancer pain
3
ketonuria
3
orthopnea
3
urinary frequency
3
dysesthesia
3
muscle stiffness
3
dry skin
3
Wind
3
decreased appetite
3
rales
3
lightheadedness
3
ENT
3
Fetal bradycardia
2
hot flashes
2
vertigo
2
Anoxia
2
tense
2
wheezing
2
blurred vision
2
sinus pressure
2
rigors
2
skin damage
2
arthralgia
2
Amputated
2
tonic-clonic seizure
2
fever of unknown origin
2
colic
2
ophthalmoplegia
2
hangover
2
myalgia
2
pelvic pain
2
loss of balance
2
hopelessness
2
breath holding
2
lassitude
2
sciatica
2
physical exhaustion
2
sinus headache
2
cardiovascular impairment
2
stridor
1
Neurologic symptoms
1
cerebellar ataxia
1
hepatosplenomegaly
1
Beau's lines
1
tinnitus
1
torticollis
1
neck pain
1
Convulsive seizure
1
masculinization
1
distraction
1
hyperemesis gravidarum
1
stomach pain
1
GI irritation
1
hyperosmia
1
microbial colonization
1
more...
Drug
Cardiovasc
705
Ethanol
81
CSF
59
9-THC
57
CPR
53
caffeine
51
Nephron
37
Ringer's solution
35
Apomorphine
32
Clonidine
30
Dermatol
28
Atropine
25
MAP
23
nitroglycerin
22
Monit
21
IFN-gamma
18
Reserpine
18
ICI
17
NADH
17
DHT
17
DHT
17
lysine
16
Indomethacin
16
IL-2
16
ascorbate
15
Adenosine triphosphate
15
CTX
14
vitamin E
14
Portal
14
Propofol
13
Dial
13
ROS
12
PCP
12
MgSO4
12
Scopolamine
11
Medetomidine
11
Fentanyl
11
CaCl2
11
Phentolamine
11
CaCl2
10
Ouabain
10
CaCl2
10
Rolipram
10
Histamine
10
DFP
9
Cimetidine
8
Oseltamivir
8
Leaf
8
Cimetidine
8
Papaverine
7
Aprotinin
7
Fraction
7
CDP
7
Adriamycin
6
Atipamezole
6
GRF
5
Angiotensin II
5
Nitric Oxide
5
Phenytoin
5
Sulpiride
5
Pilocarpine
5
TTC
5
DMI
5
Nephron
5
Vitamin E
5
Methylprednisolone
5
ABC
5
Rimonabant
5
Theophylline
5
IFN-beta
4
ampicillin
4
Doxapram
4
Helium
4
citric acid
4
Fructose
4
Donepezil
4
Flesinoxan
4
APD
4
Thiopentone
4
CPZ
4
Captopril
4
ROC
4
CoCl2
3
Domperidone
3
G-CSF
3
Butorphanol
3
Alliance
3
lactose
3
Indocyanine green
3
Sodium nitroprusside
3
CTX
3
Gel
3
MOF
3
ETA
3
Glutathione
3
Android
3
Diphenhydramine
3
TAK
3
Mutagen
3
Bupivacaine
3
CoCl2
3
THA
3
Horizon
3
ENT
3
Salbutamol
3
CTX
3
pyridoxal phosphate
2
Indapamide
2
Quinine,
2
Salicylate
2
DDAVP
2
Menthol
2
CTC
2
Perphenazine
2
Amiloride
2
Serum albumin
2
Tubocurarine
2
Glycerol
2
Codeine
2
Lisuride
2
Albumin
2
Eptifibatide
2
ALA
2
niacin
2
Codeine
2
CER
2
Ergometrine
2
RbCl
2
RbCl
2
Dipyrone
2
Catapres
2
Amiloride
2
HCH
2
CTC
2
Pramipexole
2
Desferal
2
Methyldopa
2
NovoSeven
2
Proglumide
2
Azithromycin
2
balanced salt solution
2
Bayer
2
Ranitidine
2
Parkin
2
Parkin
2
Lubeluzole
2
CCL
2
PCB
2
EE2
2
Moclobemide
2
Cantor
2
Olvanil
2
Capsicum
2
Itraconazole
2
Piracetam
2
Posture
2
Alaproclate
2
Rompun
2
Desferal
2
Pramipexole
2
more...
Enzyme
creatine kinase
112
acetylcholinesterase
85
lactate dehydrogenase
74
caspase-3
71
superoxide dismutase
66
mitogen-activated protein kinase
62
ATPase
56
CPR
53
monoamine oxidase
52
thrombin
48
aspartate aminotransferase
48
alanine aminotransferase
46
tissue plasminogen activator
46
ERK
44
cholinesterase
41
thromboplastin
41
NO synthase
40
peroxidase
38
catalase
37
protein kinase
35
adenylate cyclase
27
phosphodiesterase
27
protein kinase C
27
APC
23
glutathione peroxidase
20
tyrosine hydroxylase
19
renin
19
MAP
18
alkaline phosphatase
17
ACS
17
PARP
15
focal adhesion kinase
15
choline acetyltransferase
14
AST
14
collagenase
13
complex I
12
PCP
12
AMP-activated protein kinase
12
alcohol dehydrogenase
11
succinate dehydrogenase
11
NOS
11
caspase-8
11
lipase
10
caspase-1
10
MIP
10
xanthine oxidase
10
cytochrome oxidase
9
proteasome
9
MEK
8
BAT
8
ACE
8
guanylate cyclase
8
glucose-6-phosphate dehydrogenase
8
phospholipase A2
8
glutamate dehydrogenase
8
arginase
7
AMPK
7
CPT
7
GSK
7
heme oxygenase
7
FAST
7
reverse transcriptase
7
glutamate dehydrogenase
7
ceruloplasmin
7
glutamate dehydrogenase
7
calcineurin
6
phospholipase C
6
IKK
6
adenosine deaminase
6
hyaluronidase
6
tryptophan hydroxylase
6
P-glycoprotein
6
trypsin
6
neuraminidase
6
CaMKII
6
AMPK
6
HPI
6
plasmin
6
urokinase-type plasminogen activator
6
kallikrein
6
monoacylglycerol lipase
6
adenosine deaminase
6
adenosine kinase
6
CD10
5
prostaglandin synthetase
5
phosphoinositide 3-kinase
5
GABA transaminase
5
MPP
5
gamma-glutamyl transpeptidase
5
caspase-9
5
deaminase
5
protein phosphatase 2A
5
DOPA decarboxylase
5
citrate synthase
5
CNPase
4
NADPH oxidase
4
NADPH-diaphorase
4
NADPH oxidase
4
acyl-CoA dehydrogenase
4
hyaluronidase
4
aldehyde dehydrogenase
4
aldehyde dehydrogenase
4
luciferase
4
glutamine synthetase
4
CPT
4
aldehyde dehydrogenase
4
ornithine decarboxylase
4
aldehyde dehydrogenase
4
aldehyde dehydrogenase
4
glutaminase
4
CPT
4
hexokinase
4
pyruvate dehydrogenase
4
glutathione S-transferase
4
heparinase
4
ADH
4
SPT
3
diaphorase
3
acid phosphatase
3
enolase
3
isocitrate dehydrogenase
3
isocitrate dehydrogenase
3
glutathione reductase
3
hexosaminidase
3
diaphorase
3
SCS
3
AOR
3
HSD
3
NQO1
3
neutrophil elastase
3
SPT
3
PDK1
3
phosphorylase
3
ATP synthase
3
matrix metalloproteinase 9
3
lipoprotein lipase
3
DNA polymerase
3
demethylase
3
BIS
3
SCP
3
xanthine dehydrogenase
3
phosphofructokinase
3
DMT
3
glucose-6-phosphatase
3
endonuclease
3
tyrosine aminotransferase
2
carboxylesterase
2
thymidine kinase
2
PDE
2
DAT
2
TSA
2
malate dehydrogenase
2
PNL
2
adenylate kinase
2
pyruvate carboxylase
2
tissue kallikrein
2
chondroitinase
2
elastase
2
PAM
2
BAL
2
more...
Compound
oxygen
1448
Dec
1309
water
907
Clin
763
glucose
622
ethanol
473
calcium
441
sodium
357
5-HT
316
potassium
302
CO2
288
glutamate
234
ATP
224
noradrenaline
219
Cardiol
213
nitric oxide
171
phosphate
167
DNA
135
Cereb
123
nitrogen
113
creatinine
111
GABA
110
GABA
109
His
100
TNF
98
5-hydroxytryptophan
96
arginine
93
tyrosine
93
urea
77
sulfate
75
ADP
71
iron
69
AMP
64
Morphine
59
ammonia
59
ADP
58
ADP
58
hydrogen
57
tryptophan
55
Hearts
54
galactose
53
phosphocreatine
52
tryptophan
52
caffeine
51
Hearts
51
NMDA
50
tryptophan
50
tryptophan
50
piperazine
50
salt
49
hydroxyindoleacetic acid
46
DBA
45
DBA
45
DBA
45
HCl
45
GSH
44
ACTH
44
Naloxone
44
GSH
44
acetic acid
43
Optimal
42
TRH
42
cAMP
42
CPB
42
Neurotensin
42
leucine
42
glycerol
41
acetate
40
Neuronal
38
L-DOPA
38
phosphorus
38
prostaglandin E1
38
Lactate
38
N-acetylcysteine
38
glutamine
38
iodine
37
alanine
36
ASA
35
5-HTP
35
5-HTP
34
copper
34
Glutamate
34
prostacyclin
34
gamma-aminobutyric acid
33
N2O
33
Norepinephrine
31
lysine
28
Thyroid
28
Phe
28
Dopamine
27
PGE
27
adenylate
27
dUTP
27
Insulin
27
CPP
27
CPP
27
PGE2
27
methionine
26
Propranolol
26
Chlorpromazine
26
Propranolol
26
nicotinamide
26
NH2
25
Atropine
25
PEG
25
APAP
25
Nicotine
25
Haloperidol
24
zinc
24
Haloperidol
24
nitrate
24
Mg2+
23
4-chlorophenyl
23
TSH
23
4-chlorophenyl
23
H2S
23
cGMP
23
carbonate
21
pyridine
21
NAD
21
AEA
21
CPA
21
Gly
20
serine
20
Adenosine
20
Adrenal
20
Tetrahydrocannabinol
20
Reserpine
19
Isoproterenol
19
threonine
19
1H-pyrazole
19
Diazepam
19
Isoflurane
19
MAP
19
1H-pyrazole
19
DMSO
18
Pentobarbital
18
N-acetylaspartate
18
ICI
18
Heparin
18
ACh
18
NAD
18
bromide
17
5-HIAA
17
pyrimidine
17
Pentobarbital
17
DHT
17
NADH
17
pyrimidine
17
Verapamil
16
ammonium
16
2,4-dichlorophenyl
16
ACS
16
Verapamil
16
silver
16
2,4-dichlorophenyl
16
cysteine
16
cyanide
16
phenol
16
ACS
16
more...