Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0020672 (hypothermia)
17,327 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

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Human Gene/Protein
Sep 1182
ATP 224
Mol 221
insulin 211
CA1 210
lipopolysaccharide 210
cytokine 196
5-HT1A 180
5-hydroxytryptamine 169
hemoglobin 152
tumor necrosis factor 143
She 135
IL-6 130
CO2 127
Pol 121
GABA 107
MRI 104
caspase-3 99
TNF 98
LPS 95
neurotensin 95
albumin 87
THC 78
beta-endorphin 77
CB1 77
nitric oxide synthase 76
creatine kinase 74
IL-10 72
cannabinoid receptor 72
Gen 69
fibrinogen 68
lactate dehydrogenase 63
axonal 61
vasopressin 61
calcium channel 58
NMDA receptor 58
ADP 58
TNF-alpha 57
cage 56
interleukin-6 56
CSF 55
acetylcholinesterase 55
superoxide dismutase 55
thyroid hormone 54
opioid receptor 54
erythropoietin 53
CPR 53
CA3 52
AMP 52
ATPase 49
thrombin 49
inducible nitric oxide synthase 47
prothrombin 46
Bcl-2 45
DBA 45
bombesin 44
glial fibrillary acidic protein 44
ACTH 44
olfactory 43
muscarinic receptor 43
penumbra 42
SCH 42
CPB 42
GSH 41
gut 41
leptin 38
NMR 38
tissue plasminogen activator 38
5-HT receptor 37
aspartate aminotransferase 36
collagen 36
cyclooxygenase 36
thromboplastin 36
thyrotropin-releasing hormone 35
prolactin 35
growth hormone 35
Q10 35
5-HT2A 35
CB2 35
glucagon 34
ICP 34
interferon 33
TRH 32
Mal 31
catalase 31
neuron-specific enolase 30
mast cell 30
Rec 29
endoplasmic reticulum 29
ASA 29
uncoupling protein 1 29
5-HT1B 29
alanine aminotransferase 28
neuropeptide Y 28
cholecystokinin 28
oxytocin 28
TRPV1 28
ANOVA 28
adenosine receptor 27
HSP70 27
phosphodiesterase 27
adenylate cyclase 27
LDH 27
microsomal 26
nicotinic acetylcholine receptor 26
Mil 26
rat) 26
IgE 26
arginine vasopressin 25
GCS 25
IL-8 24
myeloperoxidase 24
serum albumin 24
NTR 24
p53 23
dopamine D2 receptor 23
uncoupling protein 23
CBF 23
ubiquitin 23
cytochrome c 23
5-HT2 receptor 23
WIN 23
c-fos 23
glutamate receptor 23
TLR4 22
mouse) 22
IL-1 22
heat shock protein 22
cold-inducible RNA-binding protein 21
Pseudomonas 20
MRS 20
tumor necrosis factor alpha 20
fur 20
ERK 20
C-reactive protein 20
CAS 20
PLA 20
lamp 19
somatostatin 19
adrenocorticotropic hormone 19
Cytokine 19
CPK 19
tyrosine hydroxylase 19
myoglobin 19
p38 19
renin 19
tau protein 18
chemokine 18
IFN-gamma 18
JNK 18
cyclooxygenase-2 18
glutathione peroxidase 18
brain-derived neurotrophic factor 18
NAD 18
cytochrome 18
MAP 18
COX-2 17
substance P 17
polypeptide 17
fatty acid amide hydrolase 17
more...
Disease
cold 1867
ischemia 1565
stroke 740
encephalopathy 594
coma 516
depression 486
cerebral ischemia 381
coagulopathy 331
sepsis 314
ventricular fibrillation 303
hypertension 301
hypoglycemia 293
sepsis 288
myocardial infarction 218
catalepsy 211
tumor 191
fits 150
cancer 147
heart failure 146
hyperglycemia 141
dehydration 136
brain edema 132
pneumonia 131
myocardial ischemia 128
prolapse 119
diabetes 119
anemia 110
heart disease 105
pulmonary hypertension 102
obesity 101
hypothyroidism 99
renal failure 95
aortic aneurysm 92
ventricular septal defect 91
Evans 89
paraplegia 85
pulmonary edema 85
cerebral palsy 84
thrombocytopenia 84
epilepsy 82
respiratory failure 79
Alzheimer's disease 79
THC 77
status epilepticus 77
SEM 77
subarachnoid hemorrhage 72
acute myocardial infarction 71
pulmonary embolism 64
congestive heart failure 64
coronary artery disease 64
malnutrition 61
disseminated intravascular coagulation 61
renal cell carcinoma 54
aortic regurgitation 52
aggression 50
cerebral infarction 50
acute renal failure 47
neonatal asphyxia 46
anaphylaxis 46
lactic acidosis 46
cognitive impairment 45
DBA 45
NAME 45
Best 45
influenza 45
atrial septal defect 45
prematurity 45
infectious diseases 42
SCH 42
alcoholism 41
hyperphagia 41
GSH 41
schizophrenia 40
myxedema 40
aortic stenosis 39
Hypoxic-ischemic encephalopathy (HIE) 37
confusion 35
adult respiratory distress syndrome 35
raised intracranial pressure 35
necrotizing enterocolitis 34
hepatic encephalopathy 34
ICP 34
Circulatory arrest 33
Brown 33
diabetic ketoacidosis 33
pancreatitis 33
atherosclerosis 32
peritonitis 31
delirium 31
mitral regurgitation 31
hypercalcemia 31
alkalosis 31
malaria 30
respiratory acidosis 30
Infection 29
bacteremia 29
suicide 28
encephalitis 28
sickle cell disease 27
West 27
Marfan syndrome 27
acute pancreatitis 27
compartment syndrome 27
cardiomyopathy 27
meningitis 27
leukopenia 27
abdominal aortic aneurysm 27
physical dependence 25
Myxedema coma 25
Parkinson's disease 25
cardiac tamponade 25
renal insufficiency 25
asthma 24
immaturity 24
chronic obstructive pulmonary disease 24
ventricular hypertrophy 23
dementia 23
hyperthyroidism 23
hepatitis 23
metastases 23
psychosis 22
virus infection 22
Wernicke's encephalopathy 22
vascular disease 22
amnesia 22
neuroblastoma 22
brain dysfunction 22
aggressiveness 22
right heart failure 21
type 2 diabetes 21
malignant hyperthermia 21
chronic renal failure 21
deep vein thrombosis 20
hydrocephalus 20
memory impairment 20
neuropathy 20
dissecting aneurysm 20
MRS 20
cirrhosis 20
anorexia nervosa 20
hypernatremia 20
multiple sclerosis 20
atrioventricular block 20
liver disease 19
hemiparesis 19
Cannabis 19
hyperbilirubinemia 19
cerebral aneurysm 19
stereotypies 19
diabetes insipidus 19
blindness 18
leukemia 18
Neonatal encephalopathy 18
akinesia 18
sudden infant death syndrome 18
uterus 18
carcinoma 18
Esophageal 18
fluid overload 17
pertussis 17
more...
Symptom
hypothermia 17327
anesthesia 1047
seizures 396
analgesia 296
pain 290
tremor 137
vomiting 124
functional recovery 118
hypercapnia 117
diarrhea 109
collapse 107
respiratory distress 103
ataxia 100
lethargy 93
anorexia 77
starvation 67
weakness 64
tachypnea 60
dyspnea 59
fatigue 56
hypotonia 46
despair 43
discomfort 43
discomfort 43
Induced hypothermia 41
exhaustion 41
sleepiness 38
nausea 38
cyanosis 37
headache 36
agitation 34
flushing 33
hyperoxia 33
angina 32
incoordination 32
hypocapnia 30
syncope 27
nausea and vomiting 25
spasm 24
oliguria 23
paraparesis 23
chills 22
abdominal pain 22
chest pain 21
regurgitation 21
cough 20
paresis 20
pallor 19
myoclonus 17
neurological disability 16
Sedation 16
dizziness 14
POA 14
constipation 13
back pain 13
hemiplegia 12
cachexia 12
erythema 11
shortness of breath 11
bradypnea 11
acute stress 11
consciousness disturbance 11
Ill 10
exertional dyspnea 10
emaciation 10
spasticity 10
memory loss 10
splenomegaly 10
hepatomegaly 9
hypoproteinemia 9
paresthesia 9
prostration 9
apathy 9
hunger 8
polyuria 8
clonus 8
aphagia 8
hemoptysis 7
dystonia 7
overweight 7
numbness 7
adipsia 7
twitching 7
excessive sweating 7
acute pain 7
polydipsia 6
chorea 6
hyperesthesia 6
hypertonia 5
muscle rigidity 5
acidity 5
thinning 5
bradykinesia 5
insomnia 5
labored breathing 5
rhinorrhea 5
catatonia 5
hoarseness 4
abnormal gait 4
asthenia 4
dysarthria 4
retching 4
hypersomnia 4
nasal discharge 3
partial seizure 3
cancer pain 3
ketonuria 3
orthopnea 3
urinary frequency 3
dysesthesia 3
muscle stiffness 3
dry skin 3
Wind 3
decreased appetite 3
rales 3
lightheadedness 3
ENT 3
Fetal bradycardia 2
hot flashes 2
vertigo 2
Anoxia 2
tense 2
wheezing 2
blurred vision 2
sinus pressure 2
rigors 2
skin damage 2
arthralgia 2
Amputated 2
tonic-clonic seizure 2
fever of unknown origin 2
colic 2
ophthalmoplegia 2
hangover 2
myalgia 2
pelvic pain 2
loss of balance 2
hopelessness 2
breath holding 2
lassitude 2
sciatica 2
physical exhaustion 2
sinus headache 2
cardiovascular impairment 2
stridor 1
Neurologic symptoms 1
cerebellar ataxia 1
hepatosplenomegaly 1
Beau's lines 1
tinnitus 1
torticollis 1
neck pain 1
Convulsive seizure 1
masculinization 1
distraction 1
hyperemesis gravidarum 1
stomach pain 1
GI irritation 1
hyperosmia 1
microbial colonization 1
more...
Drug
Cardiovasc 705
Ethanol 81
CSF 59
9-THC 57
CPR 53
caffeine 51
Nephron 37
Ringer's solution 35
Apomorphine 32
Clonidine 30
Dermatol 28
Atropine 25
MAP 23
nitroglycerin 22
Monit 21
IFN-gamma 18
Reserpine 18
ICI 17
NADH 17
DHT 17
DHT 17
lysine 16
Indomethacin 16
IL-2 16
ascorbate 15
Adenosine triphosphate 15
CTX 14
vitamin E 14
Portal 14
Propofol 13
Dial 13
ROS 12
PCP 12
MgSO4 12
Scopolamine 11
Medetomidine 11
Fentanyl 11
CaCl2 11
Phentolamine 11
CaCl2 10
Ouabain 10
CaCl2 10
Rolipram 10
Histamine 10
DFP 9
Cimetidine 8
Oseltamivir 8
Leaf 8
Cimetidine 8
Papaverine 7
Aprotinin 7
Fraction 7
CDP 7
Adriamycin 6
Atipamezole 6
GRF 5
Angiotensin II 5
Nitric Oxide 5
Phenytoin 5
Sulpiride 5
Pilocarpine 5
TTC 5
DMI 5
Nephron 5
Vitamin E 5
Methylprednisolone 5
ABC 5
Rimonabant 5
Theophylline 5
IFN-beta 4
ampicillin 4
Doxapram 4
Helium 4
citric acid 4
Fructose 4
Donepezil 4
Flesinoxan 4
APD 4
Thiopentone 4
CPZ 4
Captopril 4
ROC 4
CoCl2 3
Domperidone 3
G-CSF 3
Butorphanol 3
Alliance 3
lactose 3
Indocyanine green 3
Sodium nitroprusside 3
CTX 3
Gel 3
MOF 3
ETA 3
Glutathione 3
Android 3
Diphenhydramine 3
TAK 3
Mutagen 3
Bupivacaine 3
CoCl2 3
THA 3
Horizon 3
ENT 3
Salbutamol 3
CTX 3
pyridoxal phosphate 2
Indapamide 2
Quinine, 2
Salicylate 2
DDAVP 2
Menthol 2
CTC 2
Perphenazine 2
Amiloride 2
Serum albumin 2
Tubocurarine 2
Glycerol 2
Codeine 2
Lisuride 2
Albumin 2
Eptifibatide 2
ALA 2
niacin 2
Codeine 2
CER 2
Ergometrine 2
RbCl 2
RbCl 2
Dipyrone 2
Catapres 2
Amiloride 2
HCH 2
CTC 2
Pramipexole 2
Desferal 2
Methyldopa 2
NovoSeven 2
Proglumide 2
Azithromycin 2
balanced salt solution 2
Bayer 2
Ranitidine 2
Parkin 2
Parkin 2
Lubeluzole 2
CCL 2
PCB 2
EE2 2
Moclobemide 2
Cantor 2
Olvanil 2
Capsicum 2
Itraconazole 2
Piracetam 2
Posture 2
Alaproclate 2
Rompun 2
Desferal 2
Pramipexole 2
more...
Enzyme
creatine kinase 112
acetylcholinesterase 85
lactate dehydrogenase 74
caspase-3 71
superoxide dismutase 66
mitogen-activated protein kinase 62
ATPase 56
CPR 53
monoamine oxidase 52
thrombin 48
aspartate aminotransferase 48
alanine aminotransferase 46
tissue plasminogen activator 46
ERK 44
cholinesterase 41
thromboplastin 41
NO synthase 40
peroxidase 38
catalase 37
protein kinase 35
adenylate cyclase 27
phosphodiesterase 27
protein kinase C 27
APC 23
glutathione peroxidase 20
tyrosine hydroxylase 19
renin 19
MAP 18
alkaline phosphatase 17
ACS 17
PARP 15
focal adhesion kinase 15
choline acetyltransferase 14
AST 14
collagenase 13
complex I 12
PCP 12
AMP-activated protein kinase 12
alcohol dehydrogenase 11
succinate dehydrogenase 11
NOS 11
caspase-8 11
lipase 10
caspase-1 10
MIP 10
xanthine oxidase 10
cytochrome oxidase 9
proteasome 9
MEK 8
BAT 8
ACE 8
guanylate cyclase 8
glucose-6-phosphate dehydrogenase 8
phospholipase A2 8
glutamate dehydrogenase 8
arginase 7
AMPK 7
CPT 7
GSK 7
heme oxygenase 7
FAST 7
reverse transcriptase 7
glutamate dehydrogenase 7
ceruloplasmin 7
glutamate dehydrogenase 7
calcineurin 6
phospholipase C 6
IKK 6
adenosine deaminase 6
hyaluronidase 6
tryptophan hydroxylase 6
P-glycoprotein 6
trypsin 6
neuraminidase 6
CaMKII 6
AMPK 6
HPI 6
plasmin 6
urokinase-type plasminogen activator 6
kallikrein 6
monoacylglycerol lipase 6
adenosine deaminase 6
adenosine kinase 6
CD10 5
prostaglandin synthetase 5
phosphoinositide 3-kinase 5
GABA transaminase 5
MPP 5
gamma-glutamyl transpeptidase 5
caspase-9 5
deaminase 5
protein phosphatase 2A 5
DOPA decarboxylase 5
citrate synthase 5
CNPase 4
NADPH oxidase 4
NADPH-diaphorase 4
NADPH oxidase 4
acyl-CoA dehydrogenase 4
hyaluronidase 4
aldehyde dehydrogenase 4
aldehyde dehydrogenase 4
luciferase 4
glutamine synthetase 4
CPT 4
aldehyde dehydrogenase 4
ornithine decarboxylase 4
aldehyde dehydrogenase 4
aldehyde dehydrogenase 4
glutaminase 4
CPT 4
hexokinase 4
pyruvate dehydrogenase 4
glutathione S-transferase 4
heparinase 4
ADH 4
SPT 3
diaphorase 3
acid phosphatase 3
enolase 3
isocitrate dehydrogenase 3
isocitrate dehydrogenase 3
glutathione reductase 3
hexosaminidase 3
diaphorase 3
SCS 3
AOR 3
HSD 3
NQO1 3
neutrophil elastase 3
SPT 3
PDK1 3
phosphorylase 3
ATP synthase 3
matrix metalloproteinase 9 3
lipoprotein lipase 3
DNA polymerase 3
demethylase 3
BIS 3
SCP 3
xanthine dehydrogenase 3
phosphofructokinase 3
DMT 3
glucose-6-phosphatase 3
endonuclease 3
tyrosine aminotransferase 2
carboxylesterase 2
thymidine kinase 2
PDE 2
DAT 2
TSA 2
malate dehydrogenase 2
PNL 2
adenylate kinase 2
pyruvate carboxylase 2
tissue kallikrein 2
chondroitinase 2
elastase 2
PAM 2
BAL 2
more...
Compound
oxygen 1448
Dec 1309
water 907
Clin 763
glucose 622
ethanol 473
calcium 441
sodium 357
5-HT 316
potassium 302
CO2 288
glutamate 234
ATP 224
noradrenaline 219
Cardiol 213
nitric oxide 171
phosphate 167
DNA 135
Cereb 123
nitrogen 113
creatinine 111
GABA 110
GABA 109
His 100
TNF 98
5-hydroxytryptophan 96
arginine 93
tyrosine 93
urea 77
sulfate 75
ADP 71
iron 69
AMP 64
Morphine 59
ammonia 59
ADP 58
ADP 58
hydrogen 57
tryptophan 55
Hearts 54
galactose 53
phosphocreatine 52
tryptophan 52
caffeine 51
Hearts 51
NMDA 50
tryptophan 50
tryptophan 50
piperazine 50
salt 49
hydroxyindoleacetic acid 46
DBA 45
DBA 45
DBA 45
HCl 45
GSH 44
ACTH 44
Naloxone 44
GSH 44
acetic acid 43
Optimal 42
TRH 42
cAMP 42
CPB 42
Neurotensin 42
leucine 42
glycerol 41
acetate 40
Neuronal 38
L-DOPA 38
phosphorus 38
prostaglandin E1 38
Lactate 38
N-acetylcysteine 38
glutamine 38
iodine 37
alanine 36
ASA 35
5-HTP 35
5-HTP 34
copper 34
Glutamate 34
prostacyclin 34
gamma-aminobutyric acid 33
N2O 33
Norepinephrine 31
lysine 28
Thyroid 28
Phe 28
Dopamine 27
PGE 27
adenylate 27
dUTP 27
Insulin 27
CPP 27
CPP 27
PGE2 27
methionine 26
Propranolol 26
Chlorpromazine 26
Propranolol 26
nicotinamide 26
NH2 25
Atropine 25
PEG 25
APAP 25
Nicotine 25
Haloperidol 24
zinc 24
Haloperidol 24
nitrate 24
Mg2+ 23
4-chlorophenyl 23
TSH 23
4-chlorophenyl 23
H2S 23
cGMP 23
carbonate 21
pyridine 21
NAD 21
AEA 21
CPA 21
Gly 20
serine 20
Adenosine 20
Adrenal 20
Tetrahydrocannabinol 20
Reserpine 19
Isoproterenol 19
threonine 19
1H-pyrazole 19
Diazepam 19
Isoflurane 19
MAP 19
1H-pyrazole 19
DMSO 18
Pentobarbital 18
N-acetylaspartate 18
ICI 18
Heparin 18
ACh 18
NAD 18
bromide 17
5-HIAA 17
pyrimidine 17
Pentobarbital 17
DHT 17
NADH 17
pyrimidine 17
Verapamil 16
ammonium 16
2,4-dichlorophenyl 16
ACS 16
Verapamil 16
silver 16
2,4-dichlorophenyl 16
cysteine 16
cyanide 16
phenol 16
ACS 16
more...