Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0020672 (hypothermia)
 17,327 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Damage control surgery has become an inevitable strategy in the treatment of severely traumatized patients. Rationale for the DCS is the fact that the mortality in surgical patients who developed hypothermia, acidosis, and coagulopathy (lethal triad) is extremely high unless patients' physiologic stability was reestablished. DCS is usually indicated when patient shows signs of lethal triad during surgical operation. As most of patients who subsequently needed DCS could be judged as having most severe injuries during resuscitative phase, it may be more wise to select candidates for DCS during this phase than to indicate DCS during operation.
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PMID:[Pathophysiologic changes in trauma patients and indications of damage control surgery]. 1214 87

The liver is the most commonly injured abdominal organ. Severe hepatic trauma continue to be associated with high mortality. Management of liver injuries has changed significantly over the last two decades. Nonoperative management of hemodynamically stable patients has become the first treatment of choice. In unstable patients immediate control of bleeding is critical. In the management of severe injuries of the liver, particularly for patients who had developed a metabolic insult (hypothermia, coagulopathy, and acidosis), perihepatic packing has emerged as the key to effective damage control (DCS). The surgical aim is control of hemorrhage, preservation of sufficient hepatic function and prevention of secondary complications. Currently available surgical methods include hepatorrhaphy, resectional debridement, anatomical/nonanatomical resection, selective hepatic artery ligation, Pringle maneuver, total vascular exclusion, liver transplatation. This review discusses available diagnostic modalities and the best management options for liver injury, based on literature search and authors experience.
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PMID:[Liver injuries]. 2144 38