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Query: UMLS:C0020672 (hypothermia)
 17,327 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Two cases with acute renal failure after prolonged hypothermia are presented. Both patients were found in come, became rapidly uremic and required hemodilaysis treatment. Although the laboratory findings were typical of severe muscle damage, e.g. elevated levels of serum creatinine phosphokinase, serum lactic dehydrogenase and serum aldolase activities, visible "crush-injuries" were not found. Acute renal failure was characterized by extreme catabolism and severe metabolic acidosis. After 4 and 10 hemodialyses respectively, the patients became polyuric and finally were discharges with normal renal and muscle function. Hypotension with diminished renal perfusion and nontraumatic rhabdomyolysis due to prolonged hypothermia are regarded as the dominant pathogenetic factors in the acute renal failure.
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PMID:[Acute kidney failure in hypothermia]. 89 29

Tolerance to a 4-h altitude exposure (6,096-8,230 m) was determined in immature, young, and old male rats. The critical survival thresholds were 8,230 m for immature rats and 7,620 m for young and old rats. Hypothermia in immature rats was directly related to hypoxic severity. Body weight loss, elevated plasma corticosterone concentration, and a mean body temperature of 32.5 degrees C were characteristics of immature rats that survived at the critical threshold. Body temperature, weight change, and plasma corticosterone concentration were similar at all altitudes in young adult and old rats. Plasma enzyme activities were relatively unchanged in immature rats, but aspartate aminotransferase (EC 2.6.1.1) and lactate dehydrogenase (EC 1.1.1.27) activities in old rats, in addition to fructose-diphosphate aldolase (EC 4.1.2.13) activity in young adults, were initially elevated (P less than 0.05) at the critical survival threshold (7,620 m). Body temperature and plasma corticosterone (but not plasma enzyme activities) are important criteria for determining altitude tolerance of immature rats. However, plasma asparatate aminotransferase and lactate dehydrogenase activities are more suitable criteria for assessing tolerance in young adult and old rats.
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PMID:Age and altitude tolerance in rats: temperature, plasma enzymes, and corticosterone. 720 9