Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0020672 (
hypothermia
)
17,327
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The total cooling ef rats down to the rectal temperature 30 degrees and 20 degrees C does not change significantly the ratio of the relative specific activity of
cathepsin D
in subcellular fractions of the rat brain. The gel chromatographic analysis of heterogeneity of
cathepsin D
molecular forms in subcellular fractions established the presence of a high-molecular (in the fractions of lysosome and microsome mitochondria) and a low-molecular (in the fractions of lysosome and cytosol mitochondria) enzyme forms. Under
hypothermia
(20 degrees C) in the brain cytosol fraction there arises a minor zone of the
cathepsin D
activity corresponding to the high-molecular enzyme form.
...
PMID:[Effect of hypothermia on subcellular distribution and various physico-chemical properties of cathepsin D in rat brain]. 644 2
