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Query: UMLS:C0020672 (hypothermia)
 17,327 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Ninety-two cerebral aneurysm cases treated by clipping under moderate hypothermia are reviewed. Twenty-three of these cases received pentobarbitone during surgery in doses sufficient to render the EEG flat. The overall combined mortality and morbidity (complication rate) among 69 non-barbiturate cases was 21.7%. There were significant differences in results between aneurysms in different anatomical locations. The complication rate among eight middle cerebral artery aneurysm cases was 62.5% and among ten internal carotid artery bifurcation cases 40%, while that among nineteen internal carotid artery cases was 16% and among 27 anterior communicating complex cases 7.4%. The overall complication rate among 23 pentobarbitone cases was 17%. There were no complications among eight middle cerebral artery cases; one of two internal carotid bifurcation cases became hemiplegic following occlusion of the middle cerebral artery at is origin. The complication rate among nine internal carotid cases was 22%. No difficulties were experienced regarding haemodynamic stability or cardiac rhythm while using pentobarbitone at normothermia or at 28 degrees C. It is suggested that cerebral aneurysms involving the middle cerebral artery which appear to be most at risk may have the most to gain by the prophylactic use of pentobarbitone during surgery.
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PMID:Barbiturates for cerebral aneurysm surgery. A review of preliminary results. 402 23

A patient with a giant left middle cerebral artery aneurysm is presented. Because of previous operations and dense adhesions of the dominant frontal and temporal lobes to the aneurysm sac, we elected to obliterate the aneurysm by endaneurysmorrhaphy with the patient under hypothermia and cardiac arrest. Elective cardiac arrest has become a relatively safe, controllable procedure and may be of significant value in the treatment of difficult neurosurgical problems.
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PMID:Operative treatment of a giant cerebral artery aneurysm with hypothermia and circulatory arrest: report of a case. 738 97

Clinical perfusionists must be able to modify the existing extracorporeal circuit in order to accommodate a specific surgical pathology. The clipping of a giant intracranial middle cerebral artery aneurysm, unapproachable with conventional neurosurgical techniques, required the use of a modified closed cardiopulmonary bypass circuit combined with deep hypothermia and total circulatory arrest. In-hospital discussions with anaesthesia, cardiac surgery, neurosurgery, and cardiology enabled an informed team approach directed towards the successful treatment of this complex neurosurgical lesion.
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PMID:Extracorporeal circuit design considerations for giant intracranial aneurysm repair. 922 8