Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0020672 (hypothermia)
 17,327 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Diogenes syndrome is a syndrome described in the clinical literature in elderly individuals characterized by social isolation and extreme squalor. A number of typical features are found in the forensic evaluation of these deaths as the cases usually initiate medicolegal investigations due to the circumstances and the lack of recorded medical histories. Examinations of the death scenes are often difficult as victim's houses are in a state of disrepair, with filth and clutter, and pet dogs may resent the intrusion of strangers. Bodies are often filthy, with parasitic infestations, and are often putrefied due to the social isolation of the deceased and the delay in the finding of the corpse. Bodies may be traumatized from postmortem animal depredation by rodents or pets (eg, cats, dogs), and injuries such as bruises and lacerations may be present from falls associated with terminal illnesses or alcoholism. Blood or putrefactive fluids may be spread throughout the house by pets. Treatable medical conditions are often present in advanced stages, and features of hypothermia may be found. Attending police may suspect robbery due to disarray of the house and homicide due to apparent "bleeding" around the body from purging of putrefactive fluids, injuries from falls, or postmortem animal activity and "blood stains" throughout the house from antemortem injuries and/or fluid spread by animals. Finally, the identification of the deceased may be compromised by decay and/or postmortem animal activity. Thus, in addition to having typical clinical manifestations, such individuals appear to form a distinct subset of forensic cases having characteristic death scene and autopsy features and presenting particular difficulties in postmortem evaluations.
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PMID:Forensic issues in cases of Diogenes syndrome. 1752 74

We present a case of two brothers who died simultaneously, where their deaths could be considered to be a form of a Philemon and Baucis death; they also showed signs of Diogenes syndrome and syllogomania. The two brothers had been living in a socially isolated state and had not left their flat for months. They were found dead during the winter, in a flat with no heating. Taking the poor condition of the flat into consideration, it can be assumed that a draught existed and, therefore, the bodies were exposed to convection, that is, ventilation and low humidity, which is what caused partial mummification to the exposed areas of the body. The exact cause of death could not be determined due to the postmortem changes; however, there was very little to point to homicide or suicide as the manner of death. Despite these postmortem changes, the Wischnewski spots remained clearly visible, whose presence, in addition to the overall circumstances of the case, indicate that hypothermia could be a possible or at least contributing cause of death in both cases.
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PMID:Philemon and Baucis, Diogenes and syllogomania, Wischnewski and hypothermia--gastric mucosal lesions in partially mummified bodies. 2416 86