Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0020672 (hypothermia)
 17,327 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A patient is reported who developed adult respiratory distress syndrome (ARDS) and severe hypothermia during the decompensated phase of Wernicke encephalopathy. The absence of other causes suggests a neurogenic origin for the hypothermia, possibly as a result of lesions localized in the posterior hypothalamus. A hemodynamic study during normothermia, hypothermia and rewarming showed that at body temperatures inferior to 32 degrees C the increase in pulmonary vascular resistances seems not to be the result of a real vasoconstrictor effect in the pulmonary circulation. The Wernicke-Korsakoff syndrome may have a clinical picture similar to delirium tremens, evolving into coma with complications such as hypothermia and, possibly, ARDS.
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PMID:[Respiratory distress syndrome and hypothermia in Wernicke's encephalopathy]. 408 74

The development of hypothermia and coma are rare complications of the Wernicke-Korsakoff syndrome. This report describes three patients with Wernicke's encephalopathy in whom hypothermia was a presenting feature. The second patient described was also comatose. The frequency of occurrence and the significance of these signs are reviewed in detail, as is their potential reversibility with adequate doses of parenteral thiamine. More careful attention to the rectal temperature in patients with Wernicke's encephalopathy may reveal a higher frequency of hypothermia than has been previously suspected.
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PMID:Hypothermia and coma in the Wernicke-Korsakoff syndrome. 720 47