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Query: UMLS:C0020672 (hypothermia)
 17,327 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Juxtahepatic venous injuries are usually fatal. The optimal method of dealing with these injuries remains controversial, but most experience has been with the insertion of an atriocaval shunt. However, the mortality rate with atriocaval shunting remains prohibitively high (60% to 100%). The experience at the Bellevue Hospital Trauma and Shock Unit during a 9-year period revealed a 50% mortality rate in four consecutive patients who underwent atriocaval shunting. As such, a different approach was used in the following five patients, all of whom survived. One additional patient died in the operating room before any definitive repair could be undertaken. Four steps are considered essential to the successful management of these patients: (1) compression of the injury site until adequate resuscitation has been achieved; (2) early recognition that a juxtahepatic venous injury exists, as indicated by failure of the Pringle maneuver to adequately arrest hemorrhage; (3) prolonged portal triad occlusion with hepatocyte protection by means of large doses of steroids and topical hypothermia (portal triad occlusion time in the nonshunted group ranged from 20 to 64 minutes with a mean occlusion time of 46 minutes; although a transient rise in liver function test results seemed to correlate with the length of ischemia time, neither hepatic dysfunction nor hepatic necrosis occurred; and (4) extensive finger fracture of the liver to the site of vascular injury for primary repair or ligation; the extent of the finger fracture varied from 15 to 30 cm in length and from 5 to 15 cm in depth. The successful results achieved in five consecutive patients who sustained juxtahepatic venous injuries treated without a shunt serve as a basis for recommending this operative approach.
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PMID:The management of juxtahepatic venous injuries without an atriocaval shunt: preliminary clinical observations. 351 6

The sector scan was decisive in establishing the diagnosis of multiple rhabdomyomas of the heart in a newborn infant. Successful resection of the tumors was performed with profound hypothermia and limited cardiopulmonary bypass. Nine months later, the infant died of the complications of tuberous sclerosis. This case report documents the diagnostic accuracy of the sector scan and the potential benefit of aggressive surgical management of this condition.
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PMID:Rhabdomyoma of the heart: a diagnostic and therapeutic challenge. 736 32

We present a case of aortic aneurysm in a four-year-old child complicated with tuberous sclerosis. We used the same general principles as for adult patients and successfully managed our patient. Our methods included the use of isoflurane plus epidural anaesthesia, dopamine to maintain blood pressure, and induced mild hypothermia to reduce brain metabolism and to prevent spinal cord damage during aortic cross-clamping. Intensive monitoring including EEG was beneficial to the anaesthetic management.
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PMID:Aortic aneurysm in a four-year-old child with tuberous sclerosis. 852 13

The most significant contribution to the management of hepatic injuries over the past 5 years has been the nonoperative management of blunt injuries in the adult patient. Recent data suggest that as many as 80% of all blunt hepatic injuries may be treated in this fashion, with a success rate exceeding 95%. The fear of missing hollow viscus injuries, as well as the risk of sudden hemorrhage in the observational period, leading to an increase in hepatic-related deaths, seems exaggerated. The intraoperative management of complex hepatic injuries revolves around strict adherence to resuscitation prior to addressing the lesion itself. At times, "damage control" with termination of surgery and "packing" the patient with planned re-exploration are critical, as these maneuvers are often lifesaving. The Pringle maneuver and intrahepatic hemostasis for grades III to IV injuries have resulted in a mortality rate under 10%. Juxtahepatic venous injuries continue to carry an inordinately high mortality rate. Intracaval shunts, when used, should be inserted early in the course of the operation before excess transfusions are given and acidosis and hypothermia develop.
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PMID:Complex hepatic injuries. 878 72

The liver is the most commonly injured abdominal organ. Severe hepatic trauma continue to be associated with high mortality. Management of liver injuries has changed significantly over the last two decades. Nonoperative management of hemodynamically stable patients has become the first treatment of choice. In unstable patients immediate control of bleeding is critical. In the management of severe injuries of the liver, particularly for patients who had developed a metabolic insult (hypothermia, coagulopathy, and acidosis), perihepatic packing has emerged as the key to effective damage control (DCS). The surgical aim is control of hemorrhage, preservation of sufficient hepatic function and prevention of secondary complications. Currently available surgical methods include hepatorrhaphy, resectional debridement, anatomical/nonanatomical resection, selective hepatic artery ligation, Pringle maneuver, total vascular exclusion, liver transplatation. This review discusses available diagnostic modalities and the best management options for liver injury, based on literature search and authors experience.
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PMID:[Liver injuries]. 2144 38