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Query: UMLS:C0020672 (hypothermia)
 17,327 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A breast-fed boy, born to first-cousin parents, had been vomiting since birth; his general condition remained good until age 6 weeks when vomiting became more frequent, and his status suddenly worsened, with polypnea, shock, hypothermia, jaundice, presence of blood in urine, gastric juice, stool, and bleeding tendency during veno-punctures. There was an huge hepatomegaly and a splenomegaly. Hypoglycaemia, metabolic acidosis, severe blood coagulation disturbances, elevated liver enzymes, hypoalbuminemia, pointed to an acute liver failure. He was resuscitated with current supportive measures, and was given a wide spectrum antibiotherapy. Because serologic tests for syphilis were positive in the child and his mother, including the presence of specific IgM the infant was then given Penicillin G therapy only, which resulted in a complete recovery. One month later, a needle liver biopsy showed residual signs of hepatitis. Other possible infectious or metabolic causes of acute liver failure occurring early in life had been excluded.
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PMID:[Acute hepatic insufficiency disclosing congenital syphilis]. 240 70

A 37-year-old unmarried man was admitted because of gait disturbance and right hemifacial atrophy. Family history was unremarkable. He had an unconscious attack at age 13 and had writer's cramp since age 15. He was thin and lipodystrophic. In reviewing his portraits, hemifacial atrophy was considered to develop in his early teens and to be progressive since then. Pigmented gum, high arched palate, mild mental retardation, pseudo-Argyll Robertson's pupil, sexual impotence, amyotrophy of the left thigh and the right calf, and a limp due to bony abnormalities was detected. Serological tests for syphilis were negative. Bone X-rays disclosed coxa-deformance. Cerebrospinal fluid. EMG, EEG, muscle biopsy and brain CT were normal. Hearing was decreased to 20-35 dB bilaterally. Plasma norepinephrine levels were 450 pg/ml in the supine position and 539 pg/ml in standing. Plasma renin activity was 5.1-5.4 ng/ml/hr. Microneurography revealed highly accentuated muscle and skin sympathetic nerve activities. Hypothermia on the feet, reduced CVR-R and decreased mydriatic response to 5% cocaine instillation were present. Intravenous infusion of norepinephrine and intradermal injection of either acetylcholine or histamine revealed normal results. In the case, sympathicotonia due to dysfunction in the central nervous system is considered to be related to the pathogenesis of hemifacial atrophy.
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PMID:[Progressive hemifacial atrophy with sympathetic nerve dysfunction of central origin]. 259 49

In developing countries, child mortality declined during the 1980s, but neonatal mortality did not improve. Ministries of Health do not consider reduction of early neonatal mortality to be a priority. Underreporting of perinatal deaths is common (e.g., at least 40% of perinatal deaths). Researchers sometimes categorize perinatal deaths as other causes of infant mortality. Many people believe too technological or costly interventions are needed to reduce perinatal mortality, but simple, low-cost principles of newborn care do exist: keep the newborn warm, feed often, avoid infection, and keep the newborn close to the mother. A study in Zimbabwe shows that asphyxia, a preventable condition, occurred in 76% of cases. Prenatal care; education; improved treatment of syphilis, hypertension, diabetes, and amniotic fluid infection; closer monitoring of the fetal condition during labor; and proper management of abnormal labor would reduce perinatal deaths. Premature infants are at greater risk of death than are intrauterine growth retarded infants. Research is needed to learn more about the epidemiology, causes,, and sequelae of asphyxia as well as the most cost-effective interventions. 38% of newborns at a hospital in Kathmandu had mild or moderate hypoglycemia, 44% of whom experienced at least 3 hypoglycemic episodes in the first 2 days. Known hypoglycemic risk factors are low birth weight and hypothermia. Possible hypoglycemic risk factors are prelactal feeds and a delay in beginning breast feeding. Effective perinatal health care in developing countries requires a tired system of referral and a motivated community health worker trained to manage safe delivery and newborn care. Unfriendly staff and user charges are obstacles to primary perinatal health care, however. UNICEF's Baby Friendly Hospital initiative aims to stop distribution of free infant formula in maternity wards and to improve perinatal care.
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PMID:Perinatal health in developing countries. 846 75

A 48-year-old male patient having none of the known risk factors for atherosclerosis underwent coronary artery bypass graft (CABG) surgery because of double-vessel coronary artery disease. During the operation, the aorta, both internal thoracic arteries (L/R-ITA), and the femoral artery were sclerotic, and CABG was performed using only saphenous vein grafts. A diagnosis of tertiary syphilis had been confirmed by either microscopic or serologic tests. There were different degrees of sclerosis in different arteries of different sizes. The presence of coronary artery disease with no known atherosclerotic risk factors should include preoperative testing for connective tissue disorders, chronic inflammatory disease, and cold hemagglutinins, because of the possible use of obligatory deep hypothermia or total circulatory arrest due to a diseased ascending aorta.
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PMID:Accelerated atherosclerosis in tertiary syphilis and successful treatment with saphenous vein grafting--a case report. 1151 94

We present a 52-year-old male with a syphilitic aortic arch aneurysm accompanied by relevant extensive cerebral infarction. He was admitted to a local hospital for sudden loss of consciousness, where he was diagnosed with serious cerebral infarction. During his treatment, a multilocular aortic arch aneurysm involving the arch vessels was found incidentally. He was transferred to our hospital for surgical treatment. A preoperative routine laboratory test for syphilis was highly positive, which suggested that the aneurysm was likely caused by syphilis and the cerebral infarction was also induced by the involvement of syphilitic aortitis or arteritis. After 2 weeks of antibiotic therapy for syphilis, total arch replacement was performed successfully using meticulous brain protection with antegrade selective cerebral perfusion and deep hypothermia. He recovered without any further cerebral deficits. The pathological examination of the surgical specimen showed some characteristic changes of syphilitic aortitis.
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PMID:Successful repair of a syphilitic aortic arch aneurysm accompanied by serious cerebral infarction. 2449 65