Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0020672 (hypothermia)
 17,327 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Two cases of aortic arch aneurysm are reported. In each case, resection and replacement with a woven Dacron graft were performed with the patient in profound hypothermia and temporary circulatory arrest. Barbiturates and lidocaine provided additional cerebral protection. One patient died 27 days postoperatively of hepatic failure due to preexisting alcoholic liver cirrhosis. Clinical and autopsy studies showed intact neurological function and cerebral structures. The second patient had an uneventful postoperative course. The neurological examination, the skull computer tomogram and electroencephalogram disclosed no evidence of cerebral ischemic damage. Our findings suggest that by using barbiturates and lidocaine with profound hypothermia and temporary circulatory arrest, adequate cerebral protection for aortic arch replacement is provided.
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PMID:Aortic arch replacement with profound hypothermia and temporary circulatory arrest. 1522 98

Acute oesophageal necrosis, also known as black oesophagus, is a rare, and potentially lethal syndrome which is often diagnosed incidentally during upper endoscopy for evaluation of upper gastrointestinal bleed. It is characterised by diffuse circumferential black mucosal discolouration in the distal oesophagus secondary to necrosis that may extend proximally to involve variable length of the oesophagus. One theory of pathogenesis is that the relatively low perfusion state in the distal areas of the oesophagus makes it susceptible to mucosal injury. We present a case of acute oesophageal necrosis in a 62year-old lady with history of alcoholic cirrhosis who presented with haematemesis and severe hypothermia, and was eventually found to have acute oesophageal necrosis.
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PMID:A case of acute oesophageal necrosis (AEN) in a hypothermic patient. The grave prognosis of the black oesophagus. 2616 42