Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0020672 (hypothermia)
 17,327 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

An examination of 15 patients with postoperative aneurysms of the thoracic aorta was performed. The aneurysms were formed approximately within 15.6 years after operations on the thoracic aorta: for coarctation of the aorta--9 patients, aorta aneurysms--3 patients, open arterial ducts--1 patients, stenosing aortitis--2 patients. Operations were made on 13 patients, 2 patients were not operated upon. In 12 patients moderate hypothermia was used, one patient was operated under conditions of normothermia. The average time of the aorta compression was 42.7 min. Prostheses were used in 9 patients, lateral plasty with a synthetic flap--in 3 patients. Direct anastomosis of the aorta ends after aneurysm resection was used in 1 patient. There were no cases of paraplegia or lethal outcomes. Good results were obtained in all the patients.
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PMID:[Postoperative aneurysms of the thoracic aorta]. 272 4

Forty-nine patients with the occlusive lesions of the thoraco-abdominal aortic segment, congenital hypoplasia (13 patients) and non-specific aortitis (36 patients) were operated on. Operations were performed under moderate hypothermia (+30-31 degrees C) through the left thoracophrenolumbotomic approach. In the majority of patients reconstruction of the aorta was done by means of its resection and replacement. In 9 patients with congenital hypoplasia we performed aortic reconstruction only, and in 4 it was combined with plastic procedure on the coeliac trunk. In 25 patients with non-specific aorto-arteritis aortic replacement was combined with revascularization of the visceral (renal) arteries. In this group reconstruction of the aorta and visceral branches was performed in 7 cases, that of the aorta and renal arteries in 62 and simultaneous reconstruction of the aorta, visceral and renal arteries in 16 cases. Total mortality was 6.1% (3 patients). There was no mortality in patients with aortic hypoplasia.
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PMID:Surgical treatment of occlusive lesions of thoraco-abdominal aortic segment. 383 Nov 37

Clamping a calcified aorta during cardiac operation increases the risk of cerebral embolism by aortic debris. We operated upon a 61-year-old female with severe angina pectoris due to aortic regurgitation and bilateral coronary calcific ostial stenosis associated with porcelain aorta secondary to aortitis syndrome. At operation, cardiopulmonary bypass was begun with profound hypothermia. Using an occlusion balloon catheter inflated in the ascending aorta, the calcified aorta was incised with scissors. However accidentally the balloon was ruptured by intimal calcification of the ascending aorta, and cardiopulmonary bypass was discontinued for 11 minutes under 20 degrees C hypothermia. Extensive removal of the intimal calcification of the ascending aorta was performed with care and then, the aorta was clamped. Aortic valve replacement and triple coronary bypass operation (SVG to LAD, SVG to LCX, GEA to RCA) were performed. The proximal anastomoses of the SVGs were made on the decalcified aortic wall. The postoperative course was uneventful and aortography revealed neither dissection nor dilatation of the ascending aorta following extensive decalcification procedure of the ascending aorta, and the 3 grafts were all patent. From the experience, we learned that extensive removal of calcification of the aorta can be successfully performed in porcelain aorta due to aortitis syndrome. For CABG in aortitis syndrome, the use of ITA is rarely possible, but the GEA may be a versatile graft.
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PMID:[Aortic valve replacement and coronary artery bypass grafting in a patient with a porcelain aorta due to aortitis syndrome]. 833 35

We report herein the case of a 56-year-old man with angina pectoris suspected to be accompanied with aortitis syndrome who underwent coronary artery bypass grafting (CABG). His cerebral blood flow consisted of only that of the right vertebralartery, and the marked collaterals of the bronchial artery anastomosing to the coronary artery. CABG was performed under combined with electrical fibrillation and systemic deep hypothermia, for fear of a bad influence on the cerebral tissue by the influx of high potassium cardioplegic solution. The postoperative course was uneventful and the coronary angiography revealed that the all graft were patent.
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PMID:[Coronary arterial bypass grafting for angina pectoris suspected with aortitis syndrome: a case report]. 884 50

We report a successful reoperation of aortic valve replacement with the severely calcified, ''porcelain'' aorta due to Takayasu's disease. The patient was a 46-year-old female diagnosed with aortic prosthetic valve failure. Takayasu's aortitis had been noted at 17 years old and the patient underwent aortic valve replacement for aortic regurgitation at age 32. Chest CT scan revealed severe circumferential calcification of the whole thoracic aorta. Echocardiography revealed 100 mmHg of pressure gradient across the aortic prosthetic valve with pannus formation. Replacement of the aortic prosthetic valve was performed using the selective cerebral perfusion method under deep hypothermia. The postoperative course was uneventful without any neurological disorder. Selective cerebral perfusion was a useful method to avoid cross clamping in severely calcified ascending aortic.
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PMID:Redo aortic valve replacement with ''porcelain'' aorta in an aortitis patient. A case report. 1575 82

Wiskott-Aldrich syndrome is a primary immunodeficiency characterized by infections, thrombocytopenia, and eczema. We present a 33-year-old man with this syndrome who underwent a one-stage ascending aorta, aortic arch and descending aortic aneurysm repair under moderate hypothermia and continuous visceral and cerebral perfusion. Histologic examination showed the presence of an aortitis with granulomatous inflammatory response and multinucleated cells.
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PMID:One-step surgical approach of a thoracic aortic aneurysm in Wiskott-Aldrich syndrome. 1738 80

We present a 52-year-old male with a syphilitic aortic arch aneurysm accompanied by relevant extensive cerebral infarction. He was admitted to a local hospital for sudden loss of consciousness, where he was diagnosed with serious cerebral infarction. During his treatment, a multilocular aortic arch aneurysm involving the arch vessels was found incidentally. He was transferred to our hospital for surgical treatment. A preoperative routine laboratory test for syphilis was highly positive, which suggested that the aneurysm was likely caused by syphilis and the cerebral infarction was also induced by the involvement of syphilitic aortitis or arteritis. After 2 weeks of antibiotic therapy for syphilis, total arch replacement was performed successfully using meticulous brain protection with antegrade selective cerebral perfusion and deep hypothermia. He recovered without any further cerebral deficits. The pathological examination of the surgical specimen showed some characteristic changes of syphilitic aortitis.
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PMID:Successful repair of a syphilitic aortic arch aneurysm accompanied by serious cerebral infarction. 2449 65