Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0020639 (hypoproteinemia)
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Human Gene/Protein
mitochondrial solute carrier protein 12.5
BPntase 11.8
DGAT1 protein 11.5
protein 41 10.8
SLC25A13 10.6
ADCK4 10.5
Citrin 10.0
citrin 9.8
LARS 8.8
enteropeptidase 8.7
glutamate carrier 8.6
CD11d 8.5
THAP1 8.4
LRS 8.1
EDN 8.0
alpha-1 antitrypsin 8.0
serum protein 8.0
Eos 7.6
MICE 7.4
NEB 7.4
enterokinase 7.2
IL-1 receptor accessory protein 7.2
alpha-1-antitrypsin 6.9
Hemochromatosis 6.9
BMPR1A 6.9
TCL 6.9
mucin 2 6.8
serum amyloid A protein 6.8
Transforming growth factor beta 1 6.8
SS-A 6.8
HDS 6.7
apo AII 6.7
cubilin 6.7
MX1 6.6
L-asparaginase 6.5
AWS 6.5
Gem 6.5
FXI 6.5
SS-B 6.5
sorbitol dehydrogenase 6.4
phosphate-activated glutaminase 6.4
BCAA 6.4
Angiotensinogen 6.4
NST 6.4
laminin 5 6.4
DMC 6.4
Nephrin 6.3
Alb 6.3
prealbumin 6.2
SVD 6.2
HPS 6.1
Interleukin-10 6.1
Aspartate aminotransferase 6.1
albumin 6.1
GP1 6.1
arylsulphatase 6.0
EPH 6.0
CHL 6.0
GH1 5.9
T gamma 5.9
TER 5.9
TBS 5.9
GPT 5.9
period 3 5.9
DGAT1 5.8
argininosuccinate synthetase 5.8
K-RAS 5.8
GIST 5.8
Albumin 5.8
MUC6 5.7
TEC 5.7
factor XII 5.7
AMN 5.7
pseudocholinesterase 5.7
hGH 5.6
gastric mucin 5.5
MT-1 5.5
trypsinogen 5.5
RUNX3 5.5
serum albumin 5.4
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Disease
Carcinomatous pleurisy 13.8
hyposiderinemia 13.8
Drug-induced erythroderma 13.8
Lymphocytic-plasmacytic enteritis 13.0
Primary intestinal lymphangiectasia 12.9
Malignant glucagonoma 12.8
Steatitis 12.8
Mycobacterium avium complex lymphadenitis 12.8
Caecocolic intussusception 12.8
Celiac crisis 12.6
hypoglobulinemia 12.6
Gastrojejunocolic fistula 12.0
Regenerative anemia 12.0
Menetrier's disease 11.9
Polyclonal gammopathy 11.8
Lymphocytic gastritis 11.5
Relative polycythaemia 11.3
Secondary anemia 11.3
Hepatozoonosis 11.2
Capillary leak syndrome 11.1
Serrated adenoma 11.1
protein-losing enteropathy 10.9
Normochromic normocytic anemia 10.9
Cronkhite-Canada syndrome 10.6
Light chain deposition disease 10.3
McKittrick-Wheelock syndrome 10.2
Bright's disease 10.1
Nodular lymphoid hyperplasia 10.1
Minimal change nephrotic syndrome 10.0
Erosive esophagitis 9.9
Erythrodermic psoriasis 9.9
Autoimmune enteropathy 9.8
hepatocholangiocarcinoma 9.7
Factor XII deficiency 9.7
CTLN2 9.6
Congenital nephrotic syndrome 9.6
hyperproteinemia 9.6
hypochloremia 9.4
Lymphangiomatosis 9.3
Meige 9.3
Sandifer syndrome 9.3
Nonimmune hydrops fetalis 9.1
dysproteinemia 9.1
pseudomembranous enterocolitis 9.0
blood loss anemia 8.9
small bowel lymphoma 8.9
Toxicosis 8.9
Adrenal hemorrhage 8.9
Calcium deficiency 8.9
Enteropathy-associated T-cell lymphoma 8.8
Nephropathia epidemica 8.8
GI perforation 8.6
marginal ulcer 8.6
Griscelli syndrome 8.5
Lipedema 8.5
citrullinemia 8.5
hypochromic anemia 8.5
cerebral hematoma 8.4
Chylous ascites 8.3
hypogammaglobulinemia 8.3
acrodermatitis enteropathica 8.3
Emphysematous cystitis 8.3
lymphangiectasis 8.3
vascular rupture 8.3
nephrosis 8.3
Central serous chorioretinopathy 8.3
nephrotic syndrome 8.3
Good's syndrome 8.2
chylopericardium 8.1
Gastric antral vascular ectasia 8.1
Amebic liver abscess 8.1
azotemia 8.1
onychodystrophy 8.1
hypofibrinogenemia 8.0
jejunitis 8.0
steatorrhea 8.0
Ovarian hyperstimulation syndrome 8.0
Collagenous colitis 8.0
gastrointestinal disease 7.9
Kaposiform hemangioendothelioma 7.9
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Symptom
hypoproteinemia 14.8
Upper abdominal discomfort 14.8
dysorexia 11.5
jaundice of the skin 10.8
chyluria 9.8
swollen leg 9.0
leg edema 8.8
pedal edema 8.6
respiratory problem 8.1
inanition 8.0
periorbital edema 7.8
emaciation 7.7
abdominal fullness 7.7
oliguria 7.2
generalized pain 7.2
orthopnea 6.9
aphonia 6.8
ketonuria 6.7
abdominal discomfort 6.6
clubbing 6.6
lethargy 6.5
hyperemesis 6.5
Physical findings 6.4
testicular pain 6.3
prostration 6.2
anorexia 6.2
decreased appetite 6.2
colic 6.1
consciousness disturbance 6.1
hepatomegaly 6.1
diarrhea 6.1
tachypnea 6.1
epigastric pain 6.0
nasal discharge 6.0
stomach pain 5.8
pallor 5.8
hyperesthesia 5.7
excessive sweating 5.6
vomiting 5.4
right upper quadrant pain 5.4
abdominal pain 5.3
hepatosplenomegaly 5.3
chest tightness 5.2
intestinal bleeding 5.1
dysuria 5.1
rigors 5.1
asthenia 5.0
muscle cramps 5.0
cachexia 4.9
splenomegaly 4.8
acute abdominal pain 4.8
HSA 4.8
Postoperative pain 4.7
productive cough 4.6
hypertonia 4.5
chronic constipation 4.4
arthralgia 4.3
skin damage 4.2
polyuria 4.2
nausea 4.2
Ill 4.1
weakness 4.1
bloating 4.1
hypocapnia 4.0
numbness 4.0
incoordination 4.0
hypothermia 3.9
paresis 3.9
dyspnea 3.8
hemoptysis 3.8
regurgitation 3.8
fever of unknown origin 3.8
heartburn 3.7
chills 3.7
myalgia 3.7
polydipsia 3.7
nausea and vomiting 3.5
Wind 3.4
dry eye 3.4
erythema 3.4
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Drug
Elsamitrucin 13.2
Tryptophane 10.8
Plasmanate 10.4
Tetragastrin 10.3
Bromperidol 10.3
Camostat mesilate 10.0
Pegaspargase 9.6
Barium sulfate 9.0
Mizoribine 8.2
Imuran 8.1
Hydroxyethylstarch 8.1
Serum albumin 6.8
Zein 6.6
Prednisolone 6.2
Albumin 6.0
LMWH 5.7
Tuberculin 5.6
Everolimus 5.3
Nephron 5.0
Gelatin 5.0
Methylprednisolone 4.9
Prednisone 4.8
AraC 4.7
MDS 4.7
Infliximab 4.6
Infliximab 4.6
Nephron 4.5
Ringer's solution 4.3
IPM 4.2
VCR 4.2
TAC 4.1
Acacia 4.1
Ginseng 4.1
Captopril 3.6
TMS 3.6
vitamin E 3.3
MOF 3.2
CTX 3.0
PTH 3.0
Portal 2.7
Adriamycin 2.6
lysine 2.3
Spectrum 1.8
lactose 1.8
IL-2 1.5
Ethanol 1.5
Dial 1.5
Monit 1.3
IFN-gamma 1.0
ampicillin 0.7
Dermatol 0.5
NADH 0.4
ascorbate 0.3
CSF -0.1
Cardiovasc -1.8
Enzyme
glutaminase II 10.7
duodenase 10.1
enterokinase 7.4
sorbitol dehydrogenase 6.3
asparaginase 5.7
argininosuccinate synthetase 5.3
aspartate aminotransferase 5.0
alanine aminotransferase 4.9
AST 4.8
thromboplastin 4.7
lecithin:cholesterol acyltransferase 4.5
alpha-mannosidase 4.2
creatine kinase 4.2
ceruloplasmin 4.1
cathepsin G 4.0
gamma-glutamyl transpeptidase 4.0
glutaminase 3.9
cathepsin D 3.8
cholinesterase 3.7
alkaline phosphatase 3.7
renin 3.7
lipoprotein lipase 3.6
transglutaminase 3.5
lactate dehydrogenase 3.5
MDP 3.4
acetyl-CoA carboxylase 3.3
carboxylesterase 3.2
aldolase 3.0
beta-glucuronidase 2.9
alpha-glucosidase 2.7
plasmin 2.6
ACE 2.6
lipase 2.6
trypsin 2.6
glutamine synthetase 2.5
adenosine deaminase 2.5
adenosine deaminase 2.4
kallikrein 2.2
acetylcholinesterase 2.0
urease 2.0
urease 1.9
APC 1.8
topoisomerase 1.6
alcohol dehydrogenase 1.6
transcriptase 1.6
CD10 1.5
topoisomerase 1.5
urokinase-type plasminogen activator 1.4
lysozyme 1.4
chymotrypsin 1.4
glutathione peroxidase 1.4
tissue plasminogen activator 1.3
acid phosphatase 1.1
peroxidase 1.1
catalase 1.0
neuraminidase 1.0
beta-galactosidase 0.9
focal adhesion kinase 0.9
thrombin 0.8
adenylate cyclase 0.5
glutathione S-transferase 0.3
superoxide dismutase -0.1
RNA polymerase -0.3
luciferase -0.4
ERK -0.8
Compound
CI 515 14.8
1,2-dimethoxybenzene 10.3
Methyleugenol 10.1
Fructosamine 8.9
Trimetrexate 8.4
Bromophenol Blue 8.4
GeO2 8.3
allylbenzene 8.0
Embelin 7.9
Cystine 7.6
4-pentenoic acid 7.5
Cystine 7.4
TMQ 7.4
Triamcinolone 6.9
SAN 6.7
Chlorambucil 6.6
BEP 6.5
Perfluorooctanoic acid 6.5
Phenylbutazone 6.5
Nystatin 6.4
Nystatin 6.4
Prednisolone 6.3
Mirex 6.2
aceturate 6.2
Deltamethrin 6.2
Tranexamic acid 6.0
TBS 5.9
GPT 5.9
Methionine 5.8
Daunorubicin 5.8
Hypo 5.8
Azathioprine 5.8
Valine 5.7
TEC 5.7
Casein 5.6
Digoxin 5.5
ANCA 5.5
DMC 5.5
Albendazole 5.4
Histidine 5.3
L-PAM 5.2
Sorbitol 5.2
L-PAM 5.2
Linezolid 5.1
LCR 5.1
Methylprednisolone 5.1
norleucine 5.0
CAN 5.0
Enalapril 5.0
MSG 5.0
creatinine 4.9
Imipenem 4.9
Xenon 4.8
ALP 4.7
norleucine 4.7
Fibrin 4.7
ACI 4.6
PCM 4.6
Parenteral 4.5
Dextran 4.5
Berberine 4.5
FTA 4.5
PAN 4.5
Congo red 4.4
DEN 4.4
Isoproterenol 4.4
urea 4.4
DPA 4.3
Cap 4.3
Uric acid 4.3
PDT 4.2
A 3 4.2
Gemcitabine 4.1
CCl4 4.1
Prednisone 4.1
Gemcitabine 4.1
TAA 4.1
folinic acid 4.0
Ibuprofen 4.0
germanium 3.9
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