Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0020639 (hypoproteinemia)
 1,134 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Parenteral nutrition is a basic therapy. It is necessary to have a preoperative definition of the nutritional condition and metabolism of the surgical patient. All disturbances such as catabolism and hypoproteinemia must be analyzed and treated. Patients in good general condition who need parenteral nutrition for more than two days receive a "basic nutrition" with 0.8-1.0 g amino acids and 4-5 mg carbohydrates/kg body weight/day, which may be given via peripheral veins. A "total parenteral nutrition" is always indicated if the patient is in a marked catabolic condition pre-operatively, or if it is anticipated from the extent of the operation procedure that parenteral replacement must continue beyond four days.
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PMID:[Indications and possibilities for parenteral nutrition (author's transl)]. 10 3

A patient sustained acute third-degree radiation burns over 41% of his body surface. The burns were due to occupational injury caused by an electron accelerator. Most of his wounds appeared and spread gradually during the 10th week after the radiation burn. Subsequently, severe wound infection with methicillin-resistant Staphylococcus aureus, severe pneumonia, respiratory failure, systemic inflammatory response syndrome, nephropathy, and hypoproteinemia had developed 3 months after the radiation injury. Most of the skin grafts could neither survive nor spread on the fresh wound after removing the necrotic tissue. This phenomenon resulted in many more wounds after operations, increasing the risk of wound infection. Parenteral nutrition, respiratory support with a ventilator, antibiotics for methicillin-resistant Staphylococcus aureus, steroid therapeutics for nephropathy, deeper debridement for wounds, and skin grafting were applied for treatment of this patient. The patient recovered gradually and was discharged from the hospital in good condition after 18 months. The authors suggest that deeper excision of necrotic tissue and skin grafting as well as appropriate antibiotics are principal measures to counteract systemic inflammatory response syndrome. Sufficient albumen by vein and steroid should be administered for treatment against nephropathy and for control of infection. Functions of organs should be carefully monitored to fine-tune the therapeutic programs and to minimize complications of organs.
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PMID:Successful treatment of a case of extensive radiation burns with multiple organ dysfunction syndrome. 2266 69