Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0020639 (hypoproteinemia)
1,134 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Intraperitoneal administration of 4-pentenoic acid (20 mg/kg/day for seven days or ten doses of 50 mg/kg with 4 h intervals) or acetylsalicylic acid (50 mg/kg 1 hour after single pyrogenal injection) to rats reproduced metabolic disorders characteristic of Reye's syndrome: hyperenzymemia, hyperbilirubinemia, decreased levels of ketone bodies and urea, hypoglycemia, hypoproteinemia, accumulation of ammonia and phenol, and acidosis. Necroses and microvesicular steatosis were found in the liver.
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PMID:Experimental models of Reye's syndrome. 1097 33