Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0020639 (
hypoproteinemia
)
1,134
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Fascioliasis (Fasciola hepatica infection) was diagnosed in a herd of domestic goats in Montana. Twenty-eight goats died after a month-long clinical course of anorexia, weight loss, depression, lethargy, and decreased milk production. Clinical laboratory findings included anemia, low hemoglobin content,
hypoproteinemia
, hypoalbuminemia, eosinophilia, and high hepatic enzyme activity. The livers of affected goats had extensive parenchymal necrosis, fibrosis, and biliary hyperplasia.
Albendazole
oral suspension (20 mg/kg) was used to treat 45 of the remaining goats twice, 30 days apart; 15 goats were untreated controls. Egg counts for the untreated group averaged 171 fluke eggs per gram of feces, which compared with less than 1 epg per gram for the treated group. Fifteen percent of the treated goats died, whereas 73% of the untreated goats died. On the basis of necropsy findings, albendazole treatment was regarded as greater than 99% effective against adult F hepatica.
...
PMID:Clinical fascioliasis in domestic goats in Montana. 709 86
