Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0020639 (hypoproteinemia)
 1,134 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Of 300 congenital malformations of the lymphatics of the small intestine investigated, 120 were operated upon. Intestinal lymphography shows no injection of the cisterna chyli and histology proves that the mesenteric lymph nodes are abnormal. The induced hyperlipidemia test permits a biochemical diagnosis. Modifications of the flow of the chyle secondary to the hypoplasia of the cisterna chyli were studied: (1) in the abdominal cavity, (2) in the extraperitoneal region and the lower limb, (3) in the thorax, especially the chyle drainage channels from the diaphragm towards the cervical region. Our investigations have established that the following diseases are produced by malformation of the lymphatics of the small intestine: protein losing enteropathy, chyloperitoneum, chyluria, lymphedema with chyle reflux, chylothorax, chylopericardium, chyle reflux in the pulmonary lymphatics, hypoproteinemia and food allergies. A better understanding of the pathophysiology of the malformations of the intestinal lymphatics permits a more rational treatment of the diseases produced by this anomaly.
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PMID:Congenital malformation of the lymphatics of the small intestine. 201 16

Chylopericardium is a very rare complication after open heart surgery that is performed by median sternotomy. It is defined as uncontrollable chylous fluid loss, and may lead to hypoproteinemia, malnutrition, and immune deficiency; hence, overall increases postoperative morbidity. In this report, we present a case in which chylopericardium developed after coronary artery bypass grafting. The patient has been successfully treated; however, postoperative course was majorly complicated with the consequences of chylous fluid loss. Interestingly, the cause of the drainage was a lymphatic channel in the mediastinum. To the best of our knowledge, this is the first report in the literature in which a lymphatic channel has been demonstrated sporadically in the mediastinum as a cause of chylopericardium following open heart surgery in the adulthood.
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PMID:An interesting cause of chylopericardium after open heart surgery: a lymphatic channel. 1843 47