Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0020538 (hypertension)
 170,190 document(s) hit in 31,850,051 MEDLINE articles (0.08 seconds) .

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Human Gene/Protein
COIII protein 7.5
TRDX 7.5
FAM99A 7.5
PLEKHH3 7.5
ZNF554 7.5
C14orf68 7.5
Fibulin 2 7.5
neurofilament 3 7.5
ANKRD35 7.5
STOX2 7.5
CAV3.2 7.5
Steroid 11-beta-hydroxylase 7.5
TIGD6 7.5
LOC100129150 7.5
C2orf47 7.5
C5orf23 7.5
lethal giant larvae homolog 2 (Drosophila) 7.5
HBP 7.5
C7orf50 7.5
sorting nexin 19 7.5
FLJ20584 7.5
ribosomal protein S4, Y-linked 1 7.5
LNHR 7.5
Metaxin-2 7.5
tubulin, beta 1 7.5
NR3C2 protein 7.5
kallikrein-related peptidase 9 7.5
ALG10B 7.5
MYEOV2 7.5
SH2B3 protein 7.5
ASXL2 protein 7.5
FAM160A1 7.5
TMEM109 7.5
Parkin 2 7.5
ZNF227 7.5
Calcium/calmodulin-dependent protein kinase ID 7.5
interphotoreceptor matrix proteoglycan 1 7.5
Kelch-like protein 3 7.5
Proprotein convertase subtilisin/kexin type 2 7.5
PRKWNK4 7.5
kelch-like 3 7.4
salt-tolerant protein 7.1
OR52E4 7.1
adducin 1 7.1
alpha-adducin 6.8
WNK4 6.8
WNK1 protein 6.7
HTN 6.6
EMI5 6.5
beta hENaC 6.5
KBP-1 6.5
EML6 6.5
Endothelial nitric oxidase synthase 6.5
C12orf43 6.5
GTPase activating protein and VPS9 domains 1 6.5
Neuroblastoma suppressor of tumorigenicity 1 6.5
PRKG1 protein 6.5
SLC25A44 6.5
C4orf22 6.5
PDE4B5 6.5
chromosome 9 open reading frame 3 6.5
IFLTD1 6.5
FLJ22297 6.5
OR2C3 6.5
ZNF716 6.5
OR4C45 6.5
transforming growth factor, beta 2 6.5
anoctamin 4 6.5
B2-bradykinin receptor gene 6.5
CD164L2 6.5
chloride intracellular channel 5A 6.5
MOBKL2C 6.5
SRCAP protein 6.5
RENBP 6.5
calneuron 1 6.5
Cardiotrophin 1 6.5
TNFR1B 6.5
chromosome 6 open reading frame 10 6.5
PPIH 6.5
SOX25 6.5
more...
Disease
stage III adrenocortical cancer 7.5
IHD with angina 7.5
ACE inhibitor fetopathy 7.5
Apparent Mineralocorticoid Excess Syndrome 7.5
Renal tubular defect 7.5
Renal failure and impairment 7.5
Expanding aneurysm 7.5
Papilledema due to raised intracranial pressure 7.5
Hypertensive chronic kidney disease 7.5
Raynaud's phenomenon aggravated 7.5
Malignant nonchromaffin paraganglioma 7.5
Neonatal hypertension 7.5
Malignant renal hypertension 7.5
Hypertensive heart failure 7.5
NIDDM4 7.5
Retinal thrombosis 7.5
Secondary restless legs syndrome 7.5
Idiopathic (IPAH) 7.5
Pulmonary arteriopathy 7.5
HTNB 7.5
Aortic arteriosclerosis 7.5
Graves' disease with thyrotoxic crisis 7.5
PHA2A 7.5
Peripapillary choroidal neovascular membrane 7.5
Post-capillary pulmonary hypertension 7.5
Deficiency of vitamin D3 7.5
Exogenous hyperlipemia 7.5
Asymptomatic cerebrovascular disease 7.5
Renal parenchymal hypertension 7.5
Peripheral revascularisation 7.5
Withdrawal hypertension 7.5
Hypertension complicating pregnancy 7.5
Chronic adhesive pericarditis 7.5
Erythropoietic coproporphyria 7.5
Iliac artery dissection 7.5
Arterial leg ulcer 7.5
Other forms of heart disease 7.5
Haemangioblastomatosis 7.5
ODG2 7.5
tight fascia 7.5
Bladder Paraganglioma 7.5
Posner-Schlossmann syndrome 7.5
Intervillous thrombosis 7.5
Homozygous alpha thalassaemia 7.5
Arteriolar nephrosclerosis 7.5
PHA2C 7.5
Acute lead nephropathy 7.5
complications; vascular 7.5
Drug-induced impotence 7.5
hypertension 7.5
renoprival hypertension 7.5
Acute subendocardial infarction 7.5
kallikrein hypertension 7.5
hypertension with LV hypertrophy 7.5
Low-renin essential hypertension 7.5
Hyperdynamic septic shock 7.5
bradykinin hypertension 7.5
NIDDM3 7.5
Renal atherosclerosis 7.5
Achard-Thiers syndrome 7.5
PHA2B 7.5
Transient hypertension of pregnancy 7.5
Congenital Mesoblastic Nephroma 7.5
Renal parenchymal disease 7.5
Hypertensive renal failure 7.5
VSPA 7.5
postradiation hypothyroidism 7.5
Uterine displacement 7.5
Chronic nonspecific lung disease 7.5
Generalized arteriosclerosis 7.5
Bilateral renal artery stenosis 7.4
Uncontrolled hypertension 7.4
adrenal hypertension 7.3
Ask-Upmark kidney 7.3
Renovascular hypertension 7.3
Gordon's syndrome 7.2
Hypertensive emergency 7.2
Liddle's syndrome 7.2
renin-dependent hypertension 7.2
Atherosclerotic renal artery stenosis 7.2
more...
Symptom
High maternal weight gain 7.5
Malaise and fatigue 7.5
urological impairment 7.5
External compression headache 7.5
Antepartum eclampsia 7.5
Acute lumbago 7.5
Toxic symptom 7.5
Metabolic symptoms 7.5
Abdominal bruit 7.0
Paroxysmal hypertension 6.7
Red face 6.5
Multiple symptomatology 6.5
Moist rales 6.5
Junctional escape beats 6.5
cardiovascular pain 6.5
Empty delta sign 6.5
Musculoskeletal tenderness 6.5
Pericardial knock 6.5
swollen prostate 6.0
feeling feverish 6.0
Bulging fontanelle 6.0
Mucosal hyperemia 6.0
Cushingoid 5.9
Cushingoid 5.8
cardiovascular disability 5.7
Persistent dry cough 5.7
respiratory pain 5.7
feeling of malaise 5.7
bilateral carotid bruits 5.5
Cardiovascular symptoms 5.3
localized weakness 5.2
Morning headache 5.2
ear congestion 5.2
Auspitz's sign 5.2
heaviness of the head 5.0
tactile hallucination 5.0
cardiovascular impairment 5.0
Pulsatile tinnitus 4.8
Pre-existing disease 4.7
Pancreatic pain 4.7
CVA tenderness 4.7
Medusa's head 4.7
Digital necrosis 4.7
cardialgia 4.7
prickling sensation 4.6
pedal edema 4.6
Transient neurological symptoms 4.5
Persistent insomnia 4.5
Lower extremity weakness 4.5
Central cyanosis 4.5
renal pain 4.5
corpulence 4.5
overweight 4.4
snoring 4.4
Ortner's syndrome 4.4
Nipple pain 4.4
Dyspnea at rest 4.4
abnormal heartbeat 4.4
oliguria 4.4
angina 4.4
Sudden loss of vision 4.2
feeling of choking 4.2
High weight 4.2
Multimorbidity 4.2
sinus pressure 4.2
loin pain 4.1
unable to sleep 4.0
Orthostasis 4.0
Homan's sign 4.0
Gastrointestinal discomfort 4.0
feeling faint 4.0
excessive sweating 3.9
lightheadedness 3.9
leg edema 3.9
Induced hypothermia 3.8
precordial pain 3.8
difficulty with urination 3.8
intestinal angina 3.8
livedo 3.8
Multiple symptoms 3.7
more...
Drug
Octodrine 7.5
Pexeva 7.5
Cynt 7.5
Lycium bark 7.5
Innopran XL 7.5
Nesiritide citrate 7.5
Mexrenoate potassium 7.5
Dilevalol hydrochloride 7.5
Ecromeximab 7.5
Guancydine 7.5
Barnidipine hydrochloride 7.5
Arotinolol hydrochloride 7.5
Accupril 7.1
Mefruside 7.1
Guanadrel 7.0
Tikosyn 7.0
Tasosartan 7.0
Guanadrel sulfate 7.0
Methyldopate 7.0
INSPRA 7.0
Aliskiren 6.7
Accupro 6.7
Omapatrilat 6.7
Aramine 6.7
Olmesartan Medoxomil 6.6
Lercanidipine 6.6
Aramine 6.5
Penbutolol sulfate 6.5
Teveten 6.5
8-Hydroxy-2'-Deoxyguanosine 6.5
Tiodazosin 6.5
Posicor 6.5
Carfentanil citrate 6.5
Norvasc 6.5
Delivert 6.5
Lemildipine 6.5
Treprostinil 6.5
Lotrel 6.5
Doca 6.4
Apresoline 6.4
Trandate 6.4
Nicardipine hydrochloride 6.4
Teveten 6.4
Aldomet 6.4
Avapro 6.3
Cardura 6.3
Olmesartan 6.3
Estulic 6.3
Nebivolol 6.3
Micardis 6.3
Inversine 6.2
Trandate 6.2
Concor 6.2
Ecadotril 6.2
Atacand 6.2
Metoprolol succinate 6.2
Enalapril maleate 6.2
Trandolapril 6.2
Losartan potassium 6.2
Lacidipine 6.2
Cardura 6.2
Cilazapril 6.1
Hytrin 6.1
Clopamide 6.1
DOCP 6.1
Amlodipine besylate 6.1
Pentolinium 6.1
Perindopril 6.1
Lacidipine 6.1
Methyldopa 6.0
Isradipine 6.0
Olmesartan medoxomil 6.0
Diuril 6.0
Tiamenidine 6.0
Pindac 6.0
Ifetroban 6.0
Aliskiren fumarate 6.0
Carbenoxolone sodium 6.0
Ephedrine sulfate 6.0
Saralasin acetate 6.0
more...
Enzyme
ADAMTS13 endopeptidase 7.5
flavonol-3-O-glucoside L-rhamnosyltransferase 7.5
calpain C 7.5
renin 6.0
ACE 5.4
11beta-hydroxysteroid dehydrogenase 4.9
DszB 4.8
steroid 11beta-hydroxylase 4.7
PRA 4.7
angiotensin-converting enzyme 2 4.7
dimethylarginine dimethylaminohydrolase 4.6
aminopeptidase A 4.5
AGT 4.4
prostasin 4.3
endothelin-converting enzyme 4.2
kallikrein 4.0
aliphatic nitrilase 4.0
tissue kallikrein 4.0
prostacyclin synthase 3.9
20beta-hydroxysteroid dehydrogenase 3.9
NADPH oxidase 3.8
NO synthase 3.7
desulfinase 3.6
NADPH oxidase 3.6
PGE2-9-ketoreductase 3.5
GRK5 3.5
soluble epoxide hydrolase 3.4
small monomeric GTPase 3.4
thromboxane synthase 3.4
biliverdin reductase 3.3
pantetheinase 3.3
PAH 3.3
chymase 3.3
guanylate cyclase 3.3
aspartyl aminopeptidase 3.3
alpha-aminoadipate aminotransferase 3.2
3-mercaptopyruvate sulfurtransferase 3.1
phenylethanolamine N-methyltransferase 3.1
PHT 3.1
MAP 3.0
EC 2.6.1.4 3.0
aminopeptidase P 3.0
CPN 2.9
HSD 2.9
25-hydroxyvitamin D3 1alpha-hydroxylase 2.9
methylenetetrahydrofolate reductase 2.9
methylenetetrahydrofolate reductase 2.9
eEF2 kinase 2.8
PPH 2.8
phytanoyl-CoA hydroxylase 2.7
nicotinic acid mononucleotide adenylyltransferase 2.7
PATE 2.7
NOS 2.7
CD10 2.7
CAD 2.7
CAD 2.6
GTP cyclohydrolase I 2.6
corticosterone methyl oxidase 2.6
DSR 2.6
endothiapepsin 2.6
uricase 2.6
CAD 2.6
GRK2 2.6
phosphodiesterase 2.6
neurolysin 2.6
PKG 2.6
dopamine beta-hydroxylase 2.6
AOR 2.5
CCS 2.4
nitric oxide dioxygenase 2.4
pregnancy-associated plasma protein-A 2.4
SOR 2.4
aminopeptidase B 2.4
heme oxygenase 2.4
MT 1 2.3
phosphoamidase 2.3
GGGT 2.3
1-hydroxylase 2.2
LPL 2.2
PST 2.2
more...
Compound
C22H34O7 7.5
Vindorosine 7.5
Coronarian 7.5
Hydroxyethyl disulfide 7.5
Quinapril hydrochloride 7.1
DOPA sulfate 7.0
Guanadrel 7.0
Eprosartan 6.7
C10H15N 6.5
4-tert-butylphenyl diphenyl phosphate 6.5
Epinephrine sulfate 6.5
1H-benzo[f]isoindole-1,3(2H)-dione 6.5
Thiazide 6.3
Fosinopril 6.3
Ro 42-5892 6.2
18-Oxocortisol 6.2
Enalkiren 6.2
Chlorthalidone 6.1
Candesartan cilexetil 6.1
Eplerenone 6.1
Labetalol 6.1
Doxazosin 6.1
Telmisartan 6.1
Perindopril 6.1
PIH 6.1
Quinapril 6.1
Moxonidine 6.1
Irbesartan 6.0
2,3,3-trichloroacrylamide 6.0
F-26 6.0
Pteryxin 6.0
Inuline 6.0
Methylripariochromene A 6.0
Coleonol 6.0
Fluorohydrocortisone 6.0
C10H12O3 6.0
Perindopril erbumine 6.0
DOCA 5.9
Amlodipine 5.9
Candesartan 5.9
Minipress 5.9
Moexipril 5.9
Dihydralazine 5.9
Rilmenidine 5.9
Losartan 5.8
Petasin 5.8
Hydrochlorothiazide 5.8
Enalapril 5.8
Ang II 5.8
Ebelactone B 5.7
Urapidil 5.6
TGR 5.6
Esmolol 5.6
1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid 5.5
Benziodarone 5.5
5-cyclohexylpentanoic acid 5.5
Triuret 5.5
5-cyclohexylpentanoic acid 5.5
S 35 5.5
DBP 5.5
aldosterone 5.5
Penbutolol 5.5
Terazosin 5.5
Navidrex 5.4
Fenoldopam 5.4
Hydralazine 5.4
C10H14N2O 5.4
8,9-epoxyeicosatrienoic acid 5.4
Veratramine 5.4
20-HETE 5.4
DBP 5.4
Angiotensin II 5.4
Tempol 5.3
Spironolactone 5.3
Robinetin 5.2
C7H7N3 5.2
TDAC 5.2
Bendroflumethiazide 5.2
Labetalol hydrochloride 5.2
isodeoxycholic acid 5.2
more...