Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0020538 (
hypertension
)
170,190
document(s) hit in 31,850,051 MEDLINE articles (0.12 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
renin
12153
Sep
10407
insulin
9659
angiotensin II
7063
Ang II
3397
Mol
2903
calcium channel
2503
ACE
2161
albumin
2068
HDL
2061
collagen
1874
nitric oxide synthase
1857
She
1665
angiotensin receptor
1474
chronic renal failure
1443
hemoglobin
1434
MRI
1248
C-reactive protein
1235
endothelin-1
1175
SBP
1137
vasopressin
1090
bradykinin
1073
angiotensin II receptor
1068
angiotensinogen
1028
DBP
969
AT1
969
cytokine
913
mineralocorticoid receptor
905
leptin
893
ATPase
889
Pol
883
natriuretic peptide
859
Mal
840
fibrinogen
825
ATP
788
atrial natriuretic peptide
775
superoxide dismutase
729
Angiotensin-converting enzyme
725
vascular endothelial growth factor
668
ANG
652
tumor necrosis factor
635
endothelial nitric oxide synthase
634
Renin
626
tyrosine kinase
619
adiponectin
618
ACTH
614
phosphodiesterase
594
vascular endothelium
558
cyclooxygenase
519
TNF
518
gut
516
GFR
501
endothelin receptor
499
erythropoietin
491
atrial natriuretic factor
476
IL-6
470
Men
469
kallikrein
450
ET-1
442
catalase
440
HBP
408
parathyroid hormone
399
interleukin-6
398
proximal tubule
396
eNOS
393
CSF
364
beta-endorphin
356
cytochrome P450
351
serum albumin
341
ANOVA
335
elastin
333
arginine vasopressin
329
thrombin
327
MAP
324
sodium channel
319
fibronectin
319
guanylate cyclase
319
Rho
318
CRP
312
reserved
305
more...
Disease
hypertension
170190
diabetes
30437
obesity
15328
stroke
12305
cardiovascular disease
12024
atherosclerosis
8522
heart failure
8321
essential hypertension
7254
renal disease
6714
myocardial infarction
6315
type 2 diabetes
5481
proteinuria
5429
dyslipidemia
5362
coronary artery disease
5225
metabolic syndrome
5145
cancer
4719
coronary heart disease
4386
hyperlipidemia
4271
ventricular hypertrophy
4217
preeclampsia
4128
renal failure
3670
myocardial ischemia
3519
congestive heart failure
3401
hypercholesterolemia
3399
heart disease
3093
tumor
2954
ischemia
2716
depression
2633
pulmonary hypertension
2611
vascular disease
2421
chronic renal failure
2312
hyperglycemia
2222
anemia
1883
glucose intolerance
1781
renal artery stenosis
1754
diabetic nephropathy
1589
dementia
1580
aldosteronism
1478
renal insufficiency
1466
hyperinsulinemia
1442
obstructive sleep apnea
1436
pheochromocytoma
1396
microalbuminuria
1356
acute myocardial infarction
1344
glomerulosclerosis
1263
asthma
1238
Alzheimer's disease
1223
cardiomyopathy
1195
NAME
1179
chronic obstructive pulmonary disease
1117
systemic lupus erythematosus
1085
sleep apnea
1067
glomerulonephritis
1029
systolic hypertension
1029
chronic disease
993
retinopathy
984
plaque
976
ATM
973
abdominal obesity
913
secondary hypertension
908
osteoporosis
902
arteriosclerosis
901
cognitive impairment
898
cold
872
hyperuricemia
839
eclampsia
807
nephrotic syndrome
801
HIV
799
subarachnoid hemorrhage
789
encephalopathy
789
arthritis
773
SEM
741
Conn
734
adenoma
730
peripheral vascular disease
722
type 1 diabetes
700
renal impairment
696
sepsis
695
cirrhosis
692
Cushing's syndrome
680
more...
Symptom
overweight
3031
headache
2890
angina
2330
pain
2106
anesthesia
2037
seizures
1365
fatigue
1036
dyspnea
927
vomiting
809
nausea
784
chest pain
764
diarrhea
752
weakness
704
cough
671
abdominal pain
650
dizziness
649
sleepiness
496
syncope
407
respiratory distress
402
snoring
331
insomnia
318
hypothermia
301
hypercapnia
301
back pain
294
collapse
292
analgesia
286
flushing
274
discomfort
259
constipation
250
discomfort
248
spasm
242
agitation
228
shortness of breath
226
anorexia
207
oliguria
204
tremor
201
vertigo
198
polyuria
175
tinnitus
169
ataxia
169
nausea and vomiting
161
regurgitation
151
flank pain
143
myalgia
140
exertional dyspnea
134
hemiplegia
131
arthralgia
129
cyanosis
128
asthenia
126
dysarthria
125
Ill
123
thinning
122
lethargy
122
hemoptysis
121
paresis
114
tachypnea
114
blurred vision
114
exhaustion
110
polydipsia
107
numbness
104
functional recovery
100
paresthesia
92
hypocapnia
86
pallor
80
low back pain
80
masculinization
75
acute stress
74
epigastric pain
74
splenomegaly
70
Cushingoid
67
chills
66
Cushingoid
66
hepatomegaly
65
livedo
63
hyperoxia
63
dystonia
63
erythema
60
sinus pressure
52
leg edema
52
neck pain
52
more...
Drug
Cardiovasc
4808
Angiotensin II
1102
Nephron
619
Captopril
600
Dial
553
Monit
523
nitroglycerin
450
MAP
381
CSF
378
Nephron
358
Dermatol
335
caffeine
285
lysine
281
ascorbate
275
vitamin E
232
ETA
205
ROS
203
Clonidine
195
Atenolol
165
Indomethacin
153
Aliskiren
150
Valsartan
150
Bevacizumab
146
Ramipril
143
ROC
137
Ouabain
135
Bosentan
125
Bosentan
125
Hydrochlorothiazide
121
Perindopril
119
Nebivolol
110
PTH
107
Fructose
92
Isradipine
89
Olmesartan
88
Spectrum
86
Sodium nitroprusside
86
Nitric Oxide
84
NADH
84
Tacrolimus
82
Triclosan
78
Felodipine
77
Asthma
76
Albumin
76
ADM
73
EE2
71
ICI
70
Indapamide
68
Heme
67
ENT
66
CTX
62
Ethanol
61
Indapamide
61
niacin
61
Sorafenib
59
Leaf
59
Methyldopa
56
BH4
56
Coral
54
Dakar
53
Atropine
53
EPI
52
Cilazapril
52
MRC
51
EPA
50
Lacidipine
49
Amiloride
48
Simvastatin
48
Trandolapril
47
MgSO4
46
CaCl2
45
IL-2
45
Amiloride
45
Fenoldopam
43
Gel
43
Phentolamine
43
CaCl2
43
Estrogens
43
CaCl2
43
Viagra
42
more...
Enzyme
renin
12154
ACE
4185
NO synthase
1083
ATPase
971
mitogen-activated protein kinase
921
superoxide dismutase
858
NADPH oxidase
846
NADPH oxidase
656
ERK
618
protein kinase
602
phosphodiesterase
596
protein kinase C
577
kallikrein
529
catalase
500
guanylate cyclase
436
CD10
338
MAP
324
thrombin
319
calcineurin
309
alanine aminotransferase
302
tissue plasminogen activator
269
NOS
252
glutathione peroxidase
241
peroxidase
238
aspartate aminotransferase
235
PAH
235
PRA
235
alkaline phosphatase
220
focal adhesion kinase
214
creatine kinase
212
lactate dehydrogenase
208
11beta-hydroxysteroid dehydrogenase
208
luciferase
201
xanthine oxidase
199
phospholipase C
182
AMP-activated protein kinase
181
tyrosine hydroxylase
178
adenylate cyclase
151
CAD
148
CAD
148
CAD
148
angiotensin-converting enzyme 2
145
caspase-3
139
trypsin
139
HSD
139
monoamine oxidase
134
lipoprotein lipase
128
soluble epoxide hydrolase
127
gamma-glutamyl transpeptidase
125
phosphatidylinositol 3-kinase
124
MEK
118
phospholipase A2
116
heme oxygenase
116
proteasome
109
APC
109
thromboplastin
105
tissue kallikrein
104
reverse transcriptase
104
acetylcholinesterase
103
collagenase
102
AMPK
102
lipoxygenase
91
CYP3A4
89
AGT
88
ACS
86
AMPK
83
methylenetetrahydrofolate reductase
83
methylenetetrahydrofolate reductase
83
lipase
81
arginase
79
PKG
79
PDE
76
AST
74
urokinase-type plasminogen activator
72
chymase
70
GRK5
66
elastase
65
cholinesterase
65
glutathione reductase
64
pepsin
62
more...
Compound
Clin
15314
Dec
11839
sodium
10609
glucose
7895
salt
7470
calcium
7451
Cardiol
6307
aldosterone
6132
creatinine
4979
nitric oxide
4835
oxygen
4633
water
4627
potassium
3939
acetate
3486
arginine
2453
DNA
2017
Ang II
1982
Angiotensin II
1943
noradrenaline
1464
Insulin
1228
prostacyclin
1137
DBP
971
DBP
969
urea
959
phosphate
849
cGMP
799
ATP
791
His
769
ethanol
713
CO2
689
nitrogen
680
vitamin D
675
homocysteine
664
DOCA
644
Salt
624
ACTH
616
Sodium
591
nitrate
586
iron
584
Dial
556
tyrosine
541
TNF
518
hydrogen
517
cAMP
454
Cholesterol
451
Losartan
446
sodium chloride
442
mercury
434
Adrenal
428
zinc
410
sulfate
408
Nifedipine
380
lysine
367
MAP
353
ASA
345
5-HT
327
glutamate
324
serine
320
Optimal
286
caffeine
286
alanine
280
ADP
276
phosphorus
276
Pac
263
threonine
260
Enalapril
259
Norepinephrine
259
Cyclosporine
253
nicotinamide
249
ACh
248
PGE2
247
proline
246
cadmium
244
Propranolol
244
PAH
240
Mg2+
240
cysteine
239
NADPH
239
AMP
238
NADPH
238
more...