Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0020538 (hypertension)
 170,190 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Plasma HCS levels have been measured in normal and pathological pregnant women. In the normal group HCS levels increased from 6--8 weeks till 33-34 weeks and then felt significantly. HCS pattern in prediabetic and chemical diabetic pregnant women was similar to the normal group. However HCS levels in chemical diabetics were significantly higher during the first two trimesters. HCS levels increased in twin pregnancy, diminished in cases of eclampsia, hypertension, fetal growth retardation, mole and blighted ovum, and disappeared after intrauterine death. Nothing could be deduced from the obese and Rh-isoimmunization groups. It is confirmed the value of HCS determination as an index of placental maturation. Also, insulin/HCS ratio may be of some aid in the study of carbohydrate intolerance in pregnancy.
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PMID:Human chorionic somatommamotropin (HCS) and pregnancy. Its relation with insulin. 103 1

In order to compare the extent of early carotid atherosclerosis between patients with single vascular risk factors (smoking = SMO or hypertension = HYP) and risk-free normal subjects (= HCS), we used intimal-medial wall thickness (IMT) measurements of the common carotid artery. The age- and sex-adjusted mean IMTs were significantly higher in the HYP and SMO groups than in the HCS control group (p < 0.005 and p < 0.001, respectively). The estimated yearly progression rate of IMT (average difference in IMT/year age difference) was significantly higher in the HYP and SMO groups than in the HCS group (p < 0.05). In the total group, the age, hypertension, smoking and sex accounted for 52% of the variability of IMT. Our results show that the estimated yearly progression rate of IMT is slower in healthy and risk-free volunteers than previously detected and that the smoking and hypertension have a similar effect to the progression of early atherosclerosis. This also emphasises the influence of smoking in initial vascular remodelling process.
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PMID:Influence of hypertension and smoking as the single vascular risk factors on the intima-media thickness. 1208 Nov 5