Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0020538 (hypertension)
 170,190 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Nesiritide citrate is a human brain natriuretic peptide under development by Scios for the potential treatment of congestive heart failure (CHF). An NDA was submitted to the US FDA in April 1998 for approval to market nesiritide citrate for short-term CHF. Scios is expecting to launch this product by mid-1999. Animal studies at Scios have also indicated that human brain natriuretic peptide may be useful in the management of acute hypertension associated with numerous surgical procedures. Scios has estimated the potential market for this drug to be 250-300 million dollars in the US alone.
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PMID:Nesiritide citrate (Scios). 1616 Sep 38