Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0020538 (hypertension)
 170,190 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The electrocardiographic changes in patients with malignant arterial hypertension verified by the results of the pathoanatomic heart study have been analysed. The authors suggest a new classification of coronary arteries involvement in malignant hypertension. The informative value of Sokolov-Layon's criteria in malignant arterial hypertension is discussed.
Biull Vsesoiuznogo Kardiol Nauchn Tsentra AMN SSSR 1985
PMID:[The heart in malignant arterial hypertension: comparison of the results of morphological and electrocardiographic studies]. 315

A representative sample of the population of one Moscow district (people aged 35-64) was studied. All the examined subjects were asked, how often they used alcohol. Only 31.1% of women and 14.3% of men used no alcohol at all. The highest was the percentage of persons using alcohol several times a year: 42.1% of men and 60% of women. Men using alcohol several times a week proved to have arterial hypertension more often than those not using alcohol. Among men aged 55-64 using alcohol several times a week nobody had normal blood pressure. The more alcohol people used, the less they cared for their health and the more rarely they visited a doctor.
Biull Vsesoiuznogo Kardiol Nauchn Tsentra AMN SSSR 1988
PMID:[Sociomedical characteristics of population groups differing in the frequency of alcohol consumption (population research)]. 323 58

In 181 patients with arterial hypertension of various genesis clinical-laboratory data were compared with those obtained by computed tomography of kidneys and adrenal glands for etiology verification. Computer tomography is proved to be a valuable noninvasive method for elucidation of retroperitoneal space organs pathology which can cause arterial hypertension. Hormonal-active tumors are better identified when patients are purposely selected according to the catecholamine and VMA levels as well as the state of renin-angiotensin-aldosterone system. Computer tomography allowed determination of alterations in kidneys including those not identifiable by other methods (small cysts in kidneys, tumors, concrements).
Biull Vsesoiuznogo Kardiol Nauchn Tsentra AMN SSSR 1988
PMID:[Use of computerized tomography in the study of the etiology of various forms of symptomatic arterial hypertension]. 340 40

58 patients with severe arterial hypertension (AH) refractory to antihypertensive drug therapy including beta-blockers, calcium antagonists, antiadrenergic drugs and diuretics with addition of captopril and/or minoxidil were studied. In all the patients 3-6 sessions of plasmapheresis (PA) with plasma exchange up to 30 ml/kg body weight per 1 session were performed. After the course of plasmapheresis BP depression on the average by 24% as well as restoration of sensitivity to antihypertensive drugs and elimination of signs of malignant AH in certain cases were observed. PA was not enough effective in patients with AH combined with signs of chronic renal failure. Persistent BP depression as a result of the treatment is probably caused by positive hormonal changes, improved renal function, increased sensitivity of tissue receptors of target organs to antihypertensive drugs as well as improved peripheral blood circulation.
Biull Vsesoiuznogo Kardiol Nauchn Tsentra AMN SSSR 1988
PMID:[Treatment of refractory arterial hypertension by plasmapheresis]. 340 44

Results of 408 cases of anesthesia in patients with IHD, arterial hypertension, disturbances of heart rate and conduction are analysed. Medical treatment up to the day of operation, use of anesthetics which have moderate depressive effect on the myocardial contractility and work, administration of vasodilators and beta-blockers made it possible to avoid severe disturbances of hemodynamics during the perioperative period. Perioperative myocardial infarction was observed in 5% cases of myocardial revascularization and in 0.3% of all the other operations.
Biull Vsesoiuznogo Kardiol Nauchn Tsentra AMN SSSR 1987
PMID:[Anesthetic tactics in surgical interventions in patients with cardiovascular diseases]. 342 26

After several plasmapheresis procedures 25 out of 28 patients with high arterial hypertension revealed stable BP lowering, accompanied by elimination of their refractoriness to medical therapy. Enhanced sensitivity of lymphocytes to antihypertensive drugs has been established by lymphocyte rosette-formation with allogenic erythrocytes loaded with these preparations. Plasmapheresis was followed by moderate reduction in IgA, IgM and IgG levels with their subsequent recovery to baseline values within 3-7 days. In a number of patients with drug hypersensitivity plasmapheresis contributed to a considerable attenuation of drug-induced allergy and caused a decrease in the initially elevated IgE level. Possible mechanisms of eliminating refractoriness to medical therapy by plasmapheresis are discussed.
Biull Vsesoiuznogo Kardiol Nauchn Tsentra AMN SSSR 1987
PMID:[Clinico-immunological assessment of the effectiveness of plasmapheresis in the combined therapy of patients with high arterial hypertension]. 360 31

The article presents the results of using plasmapheresis in 8 patients with high arterial hypertension refractory to drug therapy. After 2 plasmapheresis procedures a stable BP decrease was observed in all patients allowing a further decrease of hypotensive drug administration. The hypotensive effect of plasmapheresis was accompanied by an improvement of the eye fundus and of renal function, decreased proteinuria and increased sensitivity to hypotensive therapy. Possible mechanisms of post-plasmapheresis BP lowering are discussed.
Biull Vsesoiuznogo Kardiol Nauchn Tsentra AMN SSSR 1987
PMID:[Hypotensive effect of plasmapheresis in patients with severe symptomatic arterial hypertension of renal origin]. 360 38

The paper presents the results of the study of medical impact of AUCPAHP. The study was performed in an organized population comprising 43197 males aged 40-54 years, including an intervention group of 23378 subjects and a control group of 19819. The active, mainly secondary prevention of arterial hypertension in 12 collaborative centres during 3-5 years has caused a decrease in overall mortality in the intervention group by 17.3% compared with that in the control group, in stroke mortality by 52.4% and non-fatal MI morbidity by 23.9%. CHD mortality has turned out to be practically equal in the two groups.
Biull Vsesoiuznogo Kardiol Nauchn Tsentra AMN SSSR 1986
PMID:[Results of the secondary prevention of arterial hypertension. Study Group of the All-Union Collective Program for the Prevention of Arterial Hypertension (AUCPPAH)]. 370 20

The radioactive microsphere technique was used to study hemodynamic mechanisms of action of 2 calcium antagonists--foridon and nifedipine in conscious rabbits with acute hypertension evoked by immobilization. Microspheres were injected before and 5 min after bolus i.v. injection of equihypotensive (10% blood pressure drop) doses of nifedipine (30 mcg/kg) and foridon (50 mcg/kg). Nifedipine in most cases decreased cardiac index by 7% without significant changes in regional hemodynamic. After foridon injection total peripheral resistance decreased by 19% (P less than 0.05) and cardiac index increased by 18%. There were increase in blood flow: in the heart by 34% (P less than 0.05), in the skeletal muscle by 41% (P less than 0.05) and in testes by 12% (P less than 0.05). The results show that in acute stress-induced hypertension these dihydropyridine-derivatives have different hemodynamic mechanisms of action: nifedipine preferentially depress myocardial contractility, whereas foridon dilates blood vessels.
Biull Vsesoiuznogo Kardiol Nauchn Tsentra AMN SSSR 1986
PMID:[Hemodynamic mechanisms of the hypotensive action of the new calcium antagonist foridon in acute hypertension in rabbits. A comparison with nifedipine]. 380 Nov 31

Nine patients with renal insufficiency in the terminal stage, 6 with chronic diffuse glomerulonephritis and 3 with chronic pyelonephritis, underwent 402 sessions of programmed hemodialysis. All the patients had persistent high arterial hypertension, which did not yield to conventional medical treatment, complicating hemodialysis extremely, as the procedure produced a critical increase of arterial blood pressure (ABP). The patients were given new hypotensive drugs (minoxidyl, captopril, prazosine), which lowered ABP and permitted a reduction of hypotensive injections during hemodialysis. Three patients were subjected to bilateral nephrectomy, which also considerably facilitated hemodialysis in these patients.
Biull Vsesoiuznogo Kardiol Nauchn Tsentra AMN SSSR 1985
PMID:[Hemodialysis in patients with incorrigible arterial hypertension]. 389 Aug 93


<< Previous 1 2 3 4 5 Next >>