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Query: UMLS:C0020538 (hypertension)
 170,190 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The life-span of methionie-Se75-labelled thrombocytes was studied in 46 patients with ischaemic heart disease and in 5 control individuals. In ischaemic heart disease patients the platelets life-span comprised 6.6+/-0.14 days, this period being smaller in patients over 60 years of age and in males, in contrast to younger patients and females. The presence of arterial hypertension and excessive body weight did not affect the life-span of the thrombocytes. Smoking, hypercholesterolemia and hypertriglyceridemia caused a statistically significant reduction of the circulation time of labelled thrombocytes. In patients with frequent attacks of angina pectoris and with postinfarction cardiosclerosis the life time of the platelets was shorter then in patients with painless forms of the disease and in those free of myocardial infarction. In Type II hyperlipoproteidemia the circulation period of labelled platelets comprised 6.3+/-0.16 days; in Type IV -- 6.7+/-0.29 days and in normolipemia -- 7.4+/-0.30 days. A distinct inverse correlation was established between the blood plasma cholesterol and thriglycerids level and the thrombocytes life-span. It was concluded that the reduction of the life-span of thrombocytes is attributed to the consumption of platelets by the processes of atherogenesis and chronic intravascular thrombus formation.
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PMID:[Types of hyperlipoproteinemia and thrombocyte survival in ischemic heart disease]. 88 45

The paper presents the results of an examination of 62 patients with postinfarction cardiosclerosis by means of echocardiography and ultrasonic scanning. The impact of the asynergy zone on the development of cardiac insufficiency was studied with reference to the area of myocardial lesion. Myocardial hyperkinesia is characterized, its compensatory effect in postinfarction cardiosclerosis and arterial hypertension is discussed. The effect of Inderal and Ildomen on both the zones of hyperkinesia, and on the indices of cardiac haemodynamics as a whole is described.
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PMID:[Importance of myocardial asynergy zones in the development of cardiac insufficiency]. 101 9

The lipid spectrum was examined in 77 Moscow male residents aged 30-60 years in winter and in summer. The examinees were divided into 4 groups: (1) healthy subjects; (2) patients with arterial hypertension; (3) those with post-infarction cardiosclerosis; (4) those with the two abnormalities. The levels of total cholesterol, triglycerides, high density lipoprotein cholesterol, low and very low density lipoprotein cholesterol, and circulating immune complex cholesterol were measured. All the groups were demonstrated to have lower cholesterol and low density lipoprotein levels in summer than in winter, which should be taken into account in the diagnosis and treatment of atherosclerosis-associated diseases.
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PMID:[Seasonal variations of the lipid spectrum in patients with post-infarction cardiosclerosis and arterial hypertension]. 175 81

Initial manifestations of cerebrovascular pathology (CVP) in the presence of arterial hypertension (n-26) and atherosclerosis (n-428) were combined with various cardiovascular disorders ranging from cardialgia to coronary heart disease in 67.4% of the patients. Cardial disturbances were expressed as an atypical pain syndrome in 47% and as angina of effort and postinfarction cardiosclerosis in 23.2% of the patients. Electrocardiographic changes were elicited in 52.6-62% of the patients. Bicycle ergometry revealed a decrease in all parameters of tolerance to physical exercise. Disorders of the general and cerebral hemodynamics were more pronounced in atherosclerotic patients; at the first stages of cerebral pathology they predominantly presented the normokinetic type of the hemodynamics (40.6%) while its more marked forms were associated with the hypokinetic type of the circulation (52). The early diagnosis of cardial and hemodynamic disorders is necessary for the presention of acute disturbances of the cerebral circulation.
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PMID:[Cardiac and hemodynamic disorders in the pathogenesis of the initial manifestations of cerebrovascular pathology]. 293 10

721 cases of sudden coronary death (SCD) of men aged 30-59 were studied. It was found out that SCD happened in majority of cases in subjects with increased weight of heart: 44.2% of patients had heart weight of 500 g or more. A special histomorphometric study of kidneys (345 cases of SCD) revealed arterial hypertension (AH) in 41.2% of cases, which far exceeded AH incidence in the population of men of equal age. Nevertheless, not in all cases of SCD was myocardial hypertrophy caused by AH. In patients with no AH myocardial hypertrophy was usually caused by postinfarction cardiosclerosis. In certain cases of SCD without cardiosclerosis accompanied by manifest myocardial hypertrophy there were signs of dilatative or hypertrophic cardiomyopathy. The obtained results suggest that AH and increased weight of heart should be considered factors predisposing to SCD.
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PMID:[Myocardial hypertrophy, arterial hypertension and sudden cardiac death]. 296 34

A study was made of exercise tolerance and indices of central hemodynamics in 151 patients with "isolated" angina and its combination with cardialgia, arterial hypertension and postinfarctional cardiosclerosis. Daily attacks of angina of effort (III functional class) were noted in all the patients. In patients with "isolated" angina and angina in postinfarctional cardiosclerosis exercise tolerance was the lowest. It was the highest in angina combined with cardialgia. The lowest indices of cardiac output were observed in patients with "isolated" angina and angina in postinfarctional cardiosclerosis. The best effect of nitrate therapy was obtained in patients with typical angina.
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PMID:[Clinico-functional characteristics of stenocardia and the effectiveness of its treatment with nitrong and erinit]. 309 Jul 30

Prevalence and severity of arterial hypertension in 345 sudden cardiac death (SCD) cases have been assessed basing on post-mortem morphologic examination of the kidneys involving special staining and quantitation of renal arteriolar lesion. Incidence rate for arterial hypertension was determined both for the whole group of cases and subgroups recognized by a variant of myocardial damage, i.e. alcoholic cardiomyopathy, recent myocardial infarction, thrombosis, microfocal or postinfarction cardiosclerosis. SCD was found to be closely associated with arterial hypertension, evidenced by common parenchymal affections similar to chronic pyelonephritis, or rare diabetic glomerulosclerosis. The occurrence and severity of arterial hypertension varied for different subgroups, being a more frequent finding in microfocal versus postinfarction cardiosclerosis and thrombosis (52.6, 31.6 and 28.2%, respectively), and minimal in alcoholic cardiomyopathy. Comparison of arterial hypertension severity and chronic pyelonephritis incidence for the two most numerous groups demonstrated the gravest condition in postinfarction cardiosclerosis than in microfocal one. The potential role of arterial hypertension in the mechanism of cardiac sudden death is discussed.
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PMID:[Arterial hypertension and sudden cardiac death]. 336 40

Possible electrovectorcardiographic approaches to the diagnosis of hypertrophic cardiomyopathy (HCMP) are considered on the basis of a study of 85 HCMP patients, 44 coronary patients with postinfarction cardiosclerosis and arterial hypertension (CD + AH), and 83 normal subjects. Particular attention was paid to cases where myocardial scary changes and left-ventricular hypertrophy were detected electrocardiographically as their interpretation was difficult because of similar changes in the QRS complex being typical for postinfarction cardiosclerosis. An analysis of quantitative and qualitative changes in the end segment of the QRS complex demonstrated a specific pattern of repolarization shift in patients with HCMP and CD + AH. The demonstrated changes can be useful in differential diagnosis of these conditions, facilitating the interpretation of infarction-like curves that are quite common in HCMP patients.
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PMID:[Electrovectorcardiographic characteristics of shifting repolarization phase curves in patients with hypertrophic cardiomyopathy and ischemic heart disease with arterial hypertension]. 339 71

A total of 202 patients with coronary heart disease and 115 patients with hypertension were examined to study their specific and frustration characteristics. Isenk's questionnaire and Rosentsveig's test were used. In CHD and postinfarction cardiosclerosis extraversion prevailed, in hypertension intraversion was more common. The indicator of neuroticism was high among all the patients under study. The choleric temperament prevailed in angina pectoris. Choleric and melancholic peculiarities were typical of patients with postinfarction cardiosclerosis and hypertension. Extrapunitive reactions were clearly revealed by Rosenzweig's test in all the study groups.
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PMID:[Character peculiarities in patients with various forms of ischemic heart disease and hypertension]. 408 82

Proteins, animal fats, disugars and products of animal origin, refined products and daily energy content of rations were shown to be directly related to CHD morbidity (0.61-0.94), arteriosclerosis (0.70-0.96), myocardial infarction and cardiosclerosis (0.67-0.96) mortality, their association with hypertension being reverse (-0.66-0.80). Vegetable fats, starch, cellulose, hemicellulose, pectin, buns and rolls, vegetables and fruit showed reverse correlation with CHD morbidity (-0.53-0.88) as well as with arteriosclerosis (-0.57-0.95), myocardial infarction and cardiosclerosis (-0.61-0.96) mortality.
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PMID:[Correlation between chronic non-infectious diseases of the cardiovascular system and nutritional factors]. 408 86


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