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Query: UMLS:C0020538 (hypertension)
 170,190 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The problem of psychosomatic complaints in newly sober substance abusers is longstanding. While somatic symptoms are common in withdrawal generally, some patients experience symptoms which prevail to the point of distracting from the treatment of the addiction. This paper illustrates brief, collaborative interventions conducted in a treatment hospital for three such patients who had significant, persistent, and common psychosomatic difficulties: migraine, insomnia, and hypertension. The importance and utility of holistic, multimodal treatment of the patient is emphasized.
J Subst Abuse Treat 1989
PMID:Brief interventions for psychophysiological symptoms in hospitalized addicted patients. 274 9

An association between alcohol consumption, blood pressure levels and the prevalence of hypertension has been described in close to twenty population studies. The relationship is independent of ethnic group, gender, type of alcohol, cigarette smoking and obesity, but additive to effects of obesity and oral contraceptive use. Several studies show a progressive rise in blood pressure throughout the entire range of alcohol consumption. Reports indicating a threshold for the effect at around 30 g ethanol per day (three standard drinks) may be artefactual due to underreporting of drinking levels. Drinkers consuming an average of 3 or more glasses per day have three to four times the prevalence of "hypertension" compared with teetotallers. A randomized, controlled trial of moderating alcohol consumption in normotensives has confirmed a direct pressor action of alcohol and is supported by studies in hypertensives. These observations have important implications for the prevention and management of essential hypertension in most communities.
Adv Alcohol Subst Abuse 1987
PMID:Epidemiology of alcohol and hypertension. 331 May 50

Among a group of 28 elderly veterans with dilated cardiomyopathy regularly attending an outpatient heart failure clinic, half had a history of habitual heavy drinking. It was concluded that chronic heavy drinking was the only identifiable factor responsible for the heart failure in three of these patients. Eleven other patients also had chronic heavy drinking as a possible etiological factor of their heart failure in addition to Coronary Artery Disease and/or hypertension. Less than 50% of the heavy drinkers totally abstained from alcohol after seeking medical treatment although they reduced their drinking significantly. All three patients with clear alcoholic cardiomyopathy discontinued drinking and showed marked improvement in cardiac status. The discontinuation of drinking did not appear to be associated with improvement in the remaining heavy drinkers and those patients who reported a history of moderate drinking.
J Subst Abuse Treat 1987
PMID:Alcohol and dilated cardiomyopathy: incidence and correlation with clinical outcome. 343 85

Nine (9) of 23 (39.1%) consecutive persons who sought outpatient treatment for chronic cocaine dependence had detectable plasma cocaine concentrations on admission which ranged from 10.0 to 639 ng/ml (mean 146.9 +/- 202.2). Subjects with cocaine in their plasma demonstrated at least partial tolerance to acute cocaine effects in that there was no consistent presence of hypertension, tachycardia, accelerated speaking rate, hyperreflexia, or dilated pupil. Subjects who were admitted with cocaine in their plasma retained in treatment only 4.6 +/- 4.0, compared to 13.0 +/- 13.4 days among those admitted with cocaine in their plasma (P less than .05). In addition, 11 of 14 (78.6%) subjects without cocaine in plasma compared to 2 of 9 (22.2%) with cocaine in plasma produced a urine void of cocaine metabolite during treatment. (P less than .01)
J Subst Abuse Treat 1986
PMID:Cocaine plasma concentrations in persons admitted to outpatient treatment: relationship to treatment outcome. 373 75

Domestic violence affects millions of Americans, many of whom deny or refuse to admit that that they are victims of abuse. Assessing patients at risk for domestic violence is a critical aspect of providing comprehensive primary care. As social agents, with moral and ethical responsibility, primary care providers must advocate for clients in the fight against domestic violence. Primary health care agencies must adopt uniform policies that assure that all women, children, and elders at risk for abuse are screened using a simple tool that becomes part of the primary care record. Screening for abuse should become part of an annual screening process, not unlike screening patients for high blood pressure or high cholesterol. If patients are suspected of being abused, document this on the problem list so subsequent providers will know to explore the possibility of abuse with patients. Multiple forms of abuse occur in families, and signs of abuse are usually subtle in nature. Abuse may be the reason for failed office visits, noncompliance with medications, depression, and other unexplained physical and psychological signs and symptoms. If we fail to ask, we will never know how many of our patients are victims of abuse and in need of our help.
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PMID:Domestic violence: a life-span approach to assessment and intervention. 1114 28

Abuse of anabolic androgenic steroids (AAS) is associated with serious side effects, such as hypertension and fluid retention. Renal alpha(1)- and alpha(2)-adrenoceptors are implicated in the regulation of blood pressure and fluid balance. In the present study, the levels of renal alpha(1A)-, alpha(1B)-, alpha(2A)- and alpha(2B)-adrenoceptors, and spleen alpha(1B)-adrenoceptors, were quantified in tissue membranes from rats treated with the AAS nandrolone decanoate (15 mg/kg) for 14 days. The radioligands used were [(3)H]-prazosin and [(3)H]-RX821002. The nandrolone treatment caused a 50% reduction of kidney alpha(1B)-adrenoceptors (from 15 fmol/mg protein in control rats to 6.5 fmol/mg protein in treated rats). In contrast, the levels of kidney alpha(1A)-, alpha(2A)- and alpha(2B)-, and spleen alpha(1B)-adrenoceptors were unaffected. These results raise the possibility that a decreased level of kidney alpha(1B)-adrenoceptors may cause some of the effects observed on blood pressure and fluid balance in heavy abuse of AAS.
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PMID:Nandrolone treatment decreases the level of rat kidney alpha(1B)-adrenoceptors. 1286 36

Abuse, sexual satisfaction, and sexual dysfunction are issues that are not readily addressed in the African-American population, but they are on the minds of many. Ebony decided to pose these and other questions to African-American women in a survey titled, "Are You Satisfied?" Respondents were subscribers to Ebony as well as newsstand readership. Participants either filled out the survey on the Ebony website or sent in a paper copy to be tabulated. African-American women (N=7800) from all walks of life responded and discussed their abuse histories, their relationships, their ability or inability to reach orgasm, their medical histories and level of comfort in discussing their problems with their physicians, as well as many other issues. Results indicate that 37% of the sample self-reported early sexual abuse at the hands of immediate and/or extended family members; 15%-18% have been treated for high blood pressure, STDs/HIV, and/or fibroids; and 33% have experienced an inability to achieve orgasm in the last year. Of the sample 47% stated that they had not discussed these problems with their physicians.
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PMID:The Ebony Sex Survey and the sex lives of African-American women: a call to healthcare providers. 1582 37

Alcohol and stimulant abuse represents a major cause of cerebrovascular and cardiovascular disease in young adults. Although mild-to-moderate alcohol consumption has been linked to a decreased risk for stroke and CVD, excessive use is associated with an increased risk for intracranial hemorrhage and cardiomyopathy. Cocaine represents the single largest,cause of medical complications related to illegal drug use. Cocaine has been associated with cerebral infarction, intracranial hemorrhage, myocardial infarction, cardiomyopathy, and cardiac arrhythmias. Abuse of amphetamines is associated with complications similar to those of cocaine. The complications associated with stimulant abuse are thought to be primarily mediated through excess catecholamines, resulting in acute arterial hypertension, vasospasm, thrombosis, and accelerated atherosclerosis. Because many complications of alcohol and stimulant abuse are preventable and reversible, it is important to screen for these in patients with cerebrovascular and cardiovascular disease.
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PMID:Cerebrovascular and cardiovascular complications of alcohol and sympathomimetic drug abuse. 1622 66

This study describes differences in health care utilization and recorded diagnoses in a racially and ethnically diverse sample of 1175 out-of-treatment patients who screened positive for heroin and cocaine use during an outpatient visit to a drop-in clinic at an urban hospital. Blacks averaged more ED visits than Whites and higher average yearly ED charges than Hispanics (1,991 dollars vs. 1,603 dollars). Charges over two years totaled 6,111,660 dollars. Blacks were most likely to be diagnosed with injury, hypertension, cardiac disease, alcohol abuse/dependency, and sexually transmitted disease, and least likely to be diagnosed with psychiatric disease. Hispanics were most likely to be diagnosed with HIV, dental disease and drug overdoses, and least likely to be injured. Only 34% of this group of drug users was identified with a diagnosis of drug abuse or dependency.
J Ethn Subst Abuse 2006
PMID:Racial and ethnic differences in health and health care: lessons from an inner-city patient population actively using heroin and cocaine. 1663 73

This study was designed to investigate anabolic steroid users' experiences of, and motivations for, use. Five men and six women users took part in in-depth interviews. Four themes emerged: Steroid Use vs Abuse; Side-effects; Trusted Information Sources; and Social Pressure. Many users believed that steroids used in moderation were safe. Serious side-effects (liver and kidney damage, hypertension) were not significant disincentives. Information from health professionals tended to be mistrusted because it was not based on first-hand experience of use. Social support, especially from within the body building community, was an important motivator. It is concluded that intervention programmes need the support of the body building community in order to be effective.
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PMID:Experiences of anabolic steroid use: in-depth interviews with men and women body builders. 1703 57


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